The use of particle beam mass spectrometry for the measurement of impurities in a nabumetone drug substance, not easily amenable to atmospheric pressure ionisation techniques

2001 ◽  
Vol 15 (4) ◽  
pp. 265-272 ◽  
Author(s):  
Jean-Claude Wolff ◽  
Philip N. Hawtin ◽  
Soraya Monté ◽  
Michael Balogh ◽  
Tim Jones
Keyword(s):  
Mass Spectrometry ◽  
Atmospheric Pressure ◽  
Particle Beam ◽  
Drug Substance

scholarly journals Gold standard: Mass spectrometry and chromatography

2002 ◽  
Vol 24 (1) ◽  
pp. 25-27 ◽  
Author(s):  
Neil Loftus
Keyword(s):  
Mass Spectrometry ◽  
Atmospheric Pressure ◽  
Ion Trap ◽  
Structural Information ◽  
Particle Beam ◽  
Quadrupole Ion Trap ◽  
Atmospheric Pressure Ionization ◽  
New Generation ◽  
Phases Of The Moon ◽  
Considerable Range

Mass spectrometry (MS) interfaced with liquid chromatography (LC) was once considered a technology that was reserved for rather specific applications that appeared to work in sequence with the phases of the moon. Early adventures with thermospray and particle beam interfaces proved to be of limited use, and it was not until atmospheric pressure ionization established itself that we could regard LC–MS as the analytical tool of choice for a considerable range of challenges. Indeed, advances in source design and increased ion transmission have presented a new generation of instruments that use hybrid technology such as quadrupole-time of flight (QToF), ToF–ToF and quadrupole ion-trap ToF, which provide even higher levels of confidence as a consequence of higher mass accuracy and enhanced structural information.

Analysis of neonicotinoids from plant material by desorption atmospheric pressure photoionization-mass spectrometry

2015 ◽  
Vol 29 (5) ◽  
pp. 424-430 ◽  
Author(s):  
Anu Vaikkinen ◽  
Henning S. Schmidt ◽  
Iiro Kiiski ◽  
Sari Rämö ◽  
Kati Hakala ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Atmospheric Pressure ◽  
Plant Material ◽  
Atmospheric Pressure Photoionization ◽  
Photoionization Mass Spectrometry
Sign in / Sign up

Export Citation Format

Share Document