Automatic mass spectrometry method development for drug discovery: application in metabolic stability assays

Linda E. Chovan; Candace Black-Schaefer; Peter J. Dandliker; Yau Yi Lau

doi:10.1002/rcm.1735

Automatic mass spectrometry method development for drug discovery: application in metabolic stability assays

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.1735 ◽

2004 ◽

Vol 18 (24) ◽

pp. 3105-3112 ◽

Cited By ~ 31

Author(s):

Linda E. Chovan ◽

Candace Black-Schaefer ◽

Peter J. Dandliker ◽

Yau Yi Lau

Keyword(s):

Mass Spectrometry ◽

Drug Discovery ◽

Method Development ◽

Metabolic Stability ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Automatic Mass

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Trace Analysis of Multiclass Antibiotics in Food Products by Liquid Chromatography-Tandem Mass Spectrometry: Method Development

Journal of Agricultural and Food Chemistry ◽

10.1021/acs.jafc.0c05778 ◽

2021 ◽

Vol 69 (5) ◽

pp. 1656-1666

Author(s):

Min Hu ◽

Yujie Ben ◽

Ming Hung Wong ◽

Chunmiao Zheng

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Trace Analysis ◽

Method Development ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Special Considerations for Liquid Chromatography–Tandem Mass Spectrometry Method Development

Clinics in Laboratory Medicine ◽

10.1016/j.cll.2018.05.003 ◽

2018 ◽

Vol 38 (3) ◽

pp. 539-551 ◽

Cited By ~ 3

Author(s):

Brian A. Rappold

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Method Development ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Reaction monitoring of enzyme-catalyzed ester cleavage by time-resolved fluorescence and electrospray mass spectrometry: method development and comparison

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-003-2283-5 ◽

2004 ◽

Vol 378 (4) ◽

pp. 1124-1128 ◽

Cited By ~ 14

Author(s):

Tanja Steinkamp ◽

Andr� Liesener ◽

Uwe Karst

Keyword(s):

Mass Spectrometry ◽

Electrospray Mass Spectrometry ◽

Method Development ◽

Reaction Monitoring ◽

Time Resolved Fluorescence ◽

Spectrometry Method ◽

Time Resolved ◽

Mass Spectrometry Method

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Analysis of flavonoids with unified chromatography-electrospray ionization mass spectrometry—method development and application to compounds of pharmaceutical and cosmetic interest

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-020-02798-z ◽

2020 ◽

Vol 412 (24) ◽

pp. 6595-6609

Author(s):

Jérémy Molineau ◽

Manon Meunier ◽

Angéline Noireau ◽

Laëtitia Fougère ◽

Anne-Marie Petit ◽

...

Keyword(s):

Mass Spectrometry ◽

Electrospray Ionization ◽

Electrospray Ionization Mass Spectrometry ◽

Method Development ◽

Ionization Mass Spectrometry ◽

Ionization Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method

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Targeted metabolomics in cultured cells and tissues by mass spectrometry: Method development and validation

Analytica Chimica Acta ◽

10.1016/j.aca.2014.06.012 ◽

2014 ◽

Vol 845 ◽

pp. 53-61 ◽

Cited By ~ 41

Author(s):

Anas M. Abdel Rahman ◽

Judy Pawling ◽

Michael Ryczko ◽

Amy A. Caudy ◽

James W. Dennis

Keyword(s):

Mass Spectrometry ◽

Method Development ◽

Cultured Cells ◽

Targeted Metabolomics ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Method Development And Validation ◽

Development And Validation

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Combination of Chiral Capillary Electrochromatography with Electrospray Ionization Mass Spectrometry: Method Development and Assay of Warfarin Enantiomers in Human Plasma

Analytical Chemistry ◽

10.1021/ac030193j ◽

2003 ◽

Vol 75 (22) ◽

pp. 6295-6305 ◽

Cited By ~ 45

Author(s):

Jack Zheng ◽

Shahab A. Shamsi

Keyword(s):

Mass Spectrometry ◽

Electrospray Ionization ◽

Human Plasma ◽

Electrospray Ionization Mass Spectrometry ◽

Capillary Electrochromatography ◽

Method Development ◽

Ionization Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Warfarin Enantiomers

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Determination of 30 elements in colorectal biopsies by sector field inductively coupled plasma mass spectrometry: method development and preliminary baseline levels

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3016 ◽

2007 ◽

Vol 21 (11) ◽

pp. 1776-1782 ◽

Cited By ~ 13

Author(s):

Beatrice Bocca ◽

Antonella Lamazza ◽

Anna Pino ◽

Ercole De Masi ◽

Maura Iacomino ◽

...

Keyword(s):

Mass Spectrometry ◽

Inductively Coupled Plasma ◽

Method Development ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Inductively Coupled ◽

Colorectal Biopsies ◽

Plasma Mass Spectrometry ◽

Baseline Levels

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Liquid chromatography–mass spectrometry/mass spectrometry method development for the determination of carbaryl residue in honey

Pharmacognosy Magazine ◽

10.4103/pm.pm_641_18 ◽

2019 ◽

Vol 15 (64) ◽

pp. 205 ◽

Cited By ~ 2

Author(s):

Ashish Rawson ◽

S Venu ◽

K Santhi ◽

R Paranthaman ◽

K Sureshkumar

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Method Development ◽

Liquid Chromatography Mass Spectrometry ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Mass Spectrometry ◽

Mass Spectrometry Mass Spectrometry

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Chiral purity assay for Flindokalner using tandem mass spectrometry: Method development, validation, and benchmarking

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2006.12.027 ◽

2007 ◽

Vol 43 (5) ◽

pp. 1602-1608 ◽

Cited By ~ 13

Author(s):

Brandy L. Young ◽

R.G. Cooks ◽

Michelle C. Madden ◽

Michael Bair ◽

Jingpin Jia ◽

...

Keyword(s):

Mass Spectrometry ◽

Tandem Mass Spectrometry ◽

Method Development ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chiral Purity ◽

Purity Assay

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Orthogonal analytical screening for liquid chromatography–mass spectrometry method development and preparative scale-up

Journal of Chromatography A ◽

10.1016/j.chroma.2010.10.102 ◽

2011 ◽

Vol 1218 (1) ◽

pp. 74-82 ◽

Cited By ~ 5

Author(s):

Luis M. Font ◽

A. Fontana ◽

M.T. Galceran ◽

L. Iturrino ◽

V. Perez

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Method Development ◽

Scale Up ◽

Liquid Chromatography Mass Spectrometry ◽

Spectrometry Method ◽

Preparative Scale ◽

Mass Spectrometry Method ◽

Chromatography Mass Spectrometry

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