Quantification of codeine by desorption/ionization on silicon time-of-flight mass spectrometry and comparisons with liquid chromatography/mass spectrometry

2004 ◽  
Vol 18 (12) ◽  
pp. 1403-1406 ◽  
Author(s):  
Daniel B. Wall ◽  
Jeffrey W. Finch ◽  
Steven A. Cohen
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Time Of Flight ◽  
Liquid Chromatography Mass Spectrometry ◽  
Desorption Ionization ◽  
Flight Mass Spectrometry ◽  
Chromatography Mass Spectrometry

scholarly journals Identification of Fumonisin B2, HT-2 Toxin, Patulin, and Zearalenone in Dried Figs by Liquid Chromatography–Time-of-Flight Mass Spectrometry and Liquid Chromatography–Mass Spectrometry

2008 ◽  
Vol 71 (7) ◽  
pp. 1500-1504 ◽  
Author(s):  
H. Z. ŞENYUVA ◽  
J. GILBERT
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Uv Light ◽  
Time Of Flight ◽  
Fungal Metabolites ◽  
Liquid Chromatography Mass Spectrometry ◽  
Selected Ion Monitoring ◽  
Flight Mass Spectrometry ◽  
Chromatography Mass Spectrometry ◽  
Fumonisin B2

Dried figs from Turkey that were visibly moldy (or fluorescent under UV light) and thus rejected as unsuitable for human food were screened for the presence of fungal metabolites. Crude solvent extracts from individual figs were directly analyzed by liquid chromatography combined with time-of-flight mass spectrometry to generate accurate mass data for all detectable components. A comparison of these data with a metabolite database indicated the presence of fumonisins B2 and B4, patulin, HT-2 toxin, and zearalenone among various other metabolites. Portions of the same figs were reextracted and then analyzed by conventional liquid chromatography–mass spectrometry. On the basis of coincident retention times and by matching selected ion monitoring for coincident ions with that of authentic standards, the identification of fumonisin B2, HT-2 toxin, patulin, and zearalenone was confirmed.

scholarly journals Chemical Analysis of the Main Metabolites of Three Spontaneous Plants From the Saharan Area (Algeria)

2021 ◽  
Author(s):  
Imène RADJAI
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Chemical Analysis ◽  
Biological Activities ◽  
Time Of Flight ◽  
Chemical Study ◽  
Biological Functions ◽  
Liquid Chromatography Mass Spectrometry ◽  
Chromatography Mass Spectrometry ◽  
Cotula Cinerea

Spontaneous plants metabolites are more widespread for their properties and biological functions. Also, natural products have reminded diverse scientists to take a delight in their medical and insecticidal applications linked to the environmental. A variety of metabolites have a defensive function for the plants. Thus, three spontaneous plants: Caroxylon imbricatum, Tetraena alba and Cotula cinerea collected from two ecotypes and analyzed by two known conventional methods:Gas Chromatography‐Mass Spectrometry GC QTOF(quadrupole time of flight )_MS and Liquid Chromatography-Mass spectrometry LCQTOF(quadrupole time of flight )_MS. The investigation conducted out on the identification and quantification of metabolites revealed the main metabolites which have biological activities as a part of an alternative to synthetic insecticides. The chemical study showed the presence of N-Butylbenzensulfonamide and Sulfoxycaprylicacid in the three plants. N-Carboxy-methionineresidue, Butanoicacid and Valine were found in those of Cotula cinerea and Caroxylon imbricatum (Forssk.). Artomunoxanthentrione, Glycoaldehyde, Indoline, ,Benzensulfonamide and Oxoproline were detected in extracts of Caroxylon imbricatum (Forssk.) and Tetraena alba (L.f.) In addition, Pyrroline is the only compound common in Cotula cinerea and Tetraena alba (L.f.).

scholarly journals New Developments in Liquid Chromatography Mass Spectrometry for the Determination of Micropollutants

2012 ◽  
Vol 2012 ◽  
pp. 1-18 ◽  
Author(s):  
Zoraida Sosa-Ferrera ◽  
Cristina Mahugo-Santana ◽  
José Juan Santana-Rodríguez
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
High Performance ◽  
Flame Retardants ◽  
Matrix Effects ◽  
Liquid Chromatography Mass Spectrometry ◽  
Flight Mass Spectrometry ◽  
Chromatography Mass Spectrometry ◽  
Endocrine Disrupting

The combination of liquid chromatography (LC) with mass spectrometry (MS) in the environmental field has appeared as a valuable tool for the determination of micropollutants. Several groups of compounds have been considered as particularly relevant (e.g., pharmaceuticals, hormones and other endocrine-disrupting, personal care products and their metabolites, flame retardants, surfactants, and plasticizers, among others) since the same ones are continuously being released in the environment mainly as a result of the manufacturing processes, the disposal of unused or expired products, and the excreta. Because these micropollutants are not completely removed in the environment, very specific and sensitive analytical procedures are needed for their identification and quantification. High performance liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) (or LC-MS2) and especially time-of-flight mass spectrometry (TOF/MS), has allowed that many environmental contaminants that are highly polar or nonvolatile or have a high molecular weight to be analyzed or identified. In this work we present an overview focused on the developments of liquid chromatography mass spectrometry applied to the analysis of the main classes of micropollutants in aqueous and solid environmental samples. Various aspects of methodologies based on these techniques, including sample preparation (extraction/preconcentration) and matrix effects, are discussed.

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