The effect of evening primrose oil on labor induction and cervical ripening: A systematic review and meta‐analysis

2021 ◽  
Author(s):  
Maryam Moradi ◽  
Azin Niazi ◽  
Hamid Heydarian Miri ◽  
Violeta Lopez
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Labor Induction ◽  
Cervical Ripening ◽  
Evening Primrose Oil ◽  
Evening Primrose

Evening primrose oil for cervical ripening in term pregnancies: a systematic review and meta-analysis

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Shahla Hemmatzadeh ◽  
Sakineh Mohammad Alizadeh Charandabi ◽  
Afsaneh Veisy ◽  
Mojgan Mirghafourvand
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Caesarean Section Rate ◽  
Random Effect ◽  
Consort Statement ◽  
Cervical Ripening ◽  
Cochrane Library ◽  
Evening Primrose Oil ◽  
Evening Primrose ◽  
Second Stage Of Labor

Abstract Induction of labor by using available, inexpensive and non-invasive methods with the least side effects is particularly important. A systematic review was conducted to assess the effect of evening primrose oil on cervical ripening in term pregnancies. In this systematic review and meta-analysis of clinical trials, a search was carried out in PubMed, Cochrane Library, Embase, Ovid, Scopus, Clinical Trials.gov, Google Scholar and Persian databases (Magiran, SID, and IRCT.ir) for published related articles without any time limit. The Cochrane handbook was used to determine the risk of bias of the included articles. The obtained data were analyzed in RevMan and reported in forest plots. The Odds Ratio (OR) was used to find the effect of the dichotomous data and the Mean Difference (MD) for the continuous data. The heterogeneity of the studies was assessed using I2, T2 and Chi2. The random effect was used instead of fixed effect if I2 >40%. A total of 28 titles and abstracts were extracted, 9 articles entered into the meta-analysis. The meta-analysis results showed significant differences between EPO and control groups in terms of bishop score (MD=1.32; 95% CI: 0.98 to 1.66), reducing caesarean section rate (OR= 0.61; 95% CI: 0.43 to 0.86), duration of first stage of labor (MD= -98.67; 95% CI: -140.98 to -56.38) and duration of second stage of labor (MD= -10.98; 95% CI: -21.86 to -0.09). There were no significant differences in terms of birth weight (MD= 100.97; 95% CI: -11.91 to 213.84) and the frequency of induction with oxytocin (OR= 0.53; 95% CI: 0.27 to 1.01). It seems evening primrose oil be effective for cervical ripening, reducing cesarean section rate and shortening the duration of labor. Due to the high heterogeneity of the studies, the researchers recommend further researches on the subject using a standard tool based on the CONSORT statement.

Effect of evening primrose oil supplementation on lipid profile: A systematic review and meta‐analysis of randomized clinical trials

2020 ◽  
Vol 34 (10) ◽  
pp. 2628-2638
Author(s):  
Masoud Khorshidi ◽  
Meysam Zarezadeh ◽  
Omid Moradi Moghaddam ◽  
Mohammad Reza Emami ◽  
Hamed Kord‐Varkaneh ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Lipid Profile ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Evening Primrose Oil ◽  
Evening Primrose

scholarly journals Outpatient cervical ripening and labor induction: a systematic review and network meta-analysis

2022 ◽  
Vol 226 (1) ◽  
pp. S540-S541
Author(s):  
Katherine Gonzalez ◽  
Rachel Meislin ◽  
Jared T. Roeckner ◽  
Jordan McKinney ◽  
Luis Sanchez Ramos ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Labor Induction ◽  
Cervical Ripening

The Effects of Evening-Primrose Oil on Menopausal Symptoms: A Systematic Review and Meta-analysis of Randomized Controlled Trials

2020 ◽  
Vol 16 (4) ◽  
pp. 265-276
Author(s):  
Karen Christelle ◽  
Maryam Mohd Zulkfili ◽  
Norhayati Mohd Noor ◽  
Nani Draman
Keyword(s):  
Systematic Review ◽  
Postmenopausal Women ◽  
Meta Analysis ◽  
Cochrane Collaboration ◽  
Menopausal Symptoms ◽  
Musculoskeletal Symptoms ◽  
Vasomotor Symptoms ◽  
Evening Primrose Oil ◽  
Evening Primrose ◽  
Meta Analyses

Background: Evening primrose oil (EPO) has been a treatment option for reducing menopausal symptoms, but evidence for its use is inadequate. Objective: The study aimed to determine the effectiveness of EPO in treating menopausal symptoms among peri and postmenopausal women. Study design: This is a systematic review with meta-analyses of randomised clinical trials (RCTs). Methods: We searched CENTRAL, Medline, Embase and trial registries for relevant RCTs. The methodology and reporting were carried out grounded on references from the Cochrane collaboration and the preferred reporting items for systematic reviews and meta-analyses statement. Review Manager version 5.3.5 was used to perform all the statistical analyses. Results: Five RCTs, recruiting a total of 402 peri and postmenopausal women were identified. EPO did not reduce the frequency of daily vasomotor symptoms (MD 0.01 episodes, 95% CI -0.54 to 0.57, P=0.960), frequency of daytime hot flash episodes (MD -0.51 episodes, 95% CI -2.05 to 1.03, P=0.510), frequency of night sweat episodes (MD 0.33 episodes, 95% CI -0.48 to 1.13, P=0.430) and severity of vasomotor symptoms (SMD -0.45, 95% CI -1.56 to 0.66, P=0.420) in comparison to control. EPO was associated with a minimal reduction in the severity of overall menopausal symptoms in comparison to control (SMD -1.18; 95% CI-2.18 to -0.18, P=0.02). There were insufficient data to pool results for musculoskeletal symptoms, mood, sexuality, sleeping disorders and quality of life. Conclusion: EPO may reduce the severity of overall menopausal symptoms but is not effective to reduce the frequency and severity of vasomotor symptoms. The evidence quality ranged from very low to moderate. Further research is needed to enhance related evidence.

scholarly journals Clinical interventions that influence vaginal birth after cesarean delivery rates: Systematic Review & Meta-Analysis

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Aireen Wingert ◽  
Lisa Hartling ◽  
Meghan Sebastianski ◽  
Cydney Johnson ◽  
Robin Featherstone ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cesarean Delivery ◽  
Uterine Rupture ◽  
Methodological Quality ◽  
Meta Analysis ◽  
Labor Induction ◽  
Cervical Ripening ◽  
Vaginal Birth After Cesarean ◽  
Clinical Interventions ◽  
Uterine Dehiscence

Abstract Background To systematically review the literature on clinical interventions that influence vaginal birth after cesarean (VBAC) rates. Methods We searched Ovid Medline, Ovid Embase, Wiley Cochrane Library, CINAHL via EBSCOhost; and Ovid PsycINFO. Additional studies were identified by searching for clinical trial records, conference proceedings and dissertations. Limits were applied for language (English and French) and year of publication (1985 to present). Two reviewers independently screened comparative studies (randomized or non-randomized controlled trials, and observational designs) according to a priori eligibility criteria: women with prior cesarean sections; any clinical intervention or exposure intended to increase the VBAC rate; any comparator; and, outcomes reporting VBAC, uterine rupture and uterine dehiscence rates. One reviewer extracted data and a second reviewer verified for accuracy. Meta-analysis was conducted using Mantel-Haenszel (random effects model) relative risks (VBAC rate) and risk differences (uterine rupture and dehiscence). Two reviewers independently conducted methodological quality assessments using the Mixed Methods Appraisal Tool (MMAT). Results Twenty-nine studies (six trials and 23 cohorts) examined different clinical interventions affecting rates of vaginal deliveries among women with a prior cesarean delivery (CD). Methodological quality was good overall for the trials; however, concerns among the cohort studies regarding selection bias, comparability of groups and outcome measurement resulted in higher risk of bias. Interventions for labor induction, with or without cervical ripening, included pharmacologic (oxytocin, prostaglandins, misoprostol, mifepristone, epidural analgesia), non-pharmacologic (membrane sweep, amniotomy, balloon devices), and combined (pharmacologic and non-pharmacologic). Single studies with small sample sizes and event rates contributed to most comparisons, with no clear differences between groups on rates of VBAC, uterine rupture and uterine dehiscence. Conclusions This systematic review evaluated clinical interventions directed at increasing the rate of vaginal delivery among women with a prior CD and found low to very low certainty in the body of evidence for cervical ripening and/or labor induction techniques. There is insufficient high-quality evidence to inform optimal clinical interventions among women attempting a trial of labor after a prior CD.

Outpatient versus inpatient balloon catheter insertion for labor induction: A systematic review and meta-analysis of randomized controlled trials

2020 ◽  
Vol 49 (8) ◽  
pp. 101823
Author(s):  
Ahmed Mohamed Abdelhakim ◽  
Mohammad Abrar Shareef ◽  
Abdulhadi A. AlAmodi ◽  
Rehab Abdelhamid Aboshama ◽  
Mohamed Fathi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Balloon Catheter ◽  
Labor Induction ◽  
Catheter Insertion ◽  
Controlled Trials ◽  
Randomized Controlled
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