Roles of plant‐derived bioactive compounds and related microRNAs in cancer therapy

Author(s):  
Heng Zou ◽  
Yanli Li ◽  
Xiaomin Liu ◽  
Zong Wu ◽  
Jingjing Li ◽  
...  
2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Wei Liu ◽  
Binbin Yang ◽  
Lu Yang ◽  
Jasmine Kaur ◽  
Calvin Jessop ◽  
...  

Effective cancer therapy is one of the biggest global challenges. Conventional cancer therapies have been at the forefront of combating cancers, but more evidence showed considerable side effects, limiting their use. There are various new therapies in development, but combined approaches for treating cancer are much expected. Natural herbs had been traditionally in use for cancer therapy in most parts of the world. In this review, we have examined ten commonly used Chinese herbs that have, for centuries, shown effectiveness in treating cancers. They demonstrated the abilities to promote the apoptosis of cancer cells, inhibit their metastasis, activate the patient’s anticancer immunity, and synergistically increase the efficacy of conventional chemotherapy and radiation therapy when used in combination. Clinical experiences had proved that these herbs and their bioactive compounds were effective against a plethora of cancers through a variety of mechanisms, effectively improving patients’ quality of life without significant side effects. These advantages indicate that there are huge potentials in the development of Chinese herbs into cancer medicine as part of a promising, holistic cancer treatment modality.


Biomedicine ◽  
2021 ◽  
Vol 41 (4) ◽  
pp. 701-705
Author(s):  
Illyana Ismail ◽  
Veshalini Kasiraja ◽  
Hasmah Abdullah

Cancer is a life-threatening disease if not diagnosed and treated early. Available cancer treatments with undesirable side effects have led to the search for safer and more effective treatments. Therapeutic intervention using plant-derived natural products have been of great interest these days. Many plant-derived phytochemicals have been implicated with anticancer activities. Quercus infectoria is one of the prominent candidates for its chemopreventive mechanisms of action in cancer. Worldwide, this plant has been used in various medicinal purposes. Based on the available data from previous scientific researches, this review focuses on the anticancer potentials of Q. infectoria, as well as its bioactive compounds such as tannic acid, gallic acid and ellagic acid. This review will trigger of generating new insights into possible application of this plant in cancer therapy. 


2020 ◽  
Vol 246 ◽  
pp. 122841
Author(s):  
Bashir Mosayyebi ◽  
Mahsa Imani ◽  
Leila Mohammadi ◽  
Abolfazl Akbarzadeh ◽  
Nosratollah Zarghami ◽  
...  

2012 ◽  
Vol 161 ◽  
pp. 7
Author(s):  
Daniele Vergara ◽  
Raffaele Acierno ◽  
Michele Maffia

2019 ◽  
Vol 9 (4-s) ◽  
pp. 726-729
Author(s):  
Sudipta Biswas ◽  
Partha Talukdar ◽  
Dr. Soumendra Nath Talapatra

The present review deals with the bioactive compounds (phytochemicals) in the fruits and leaves of guava (Psidium guajava Linn.). In the present study, an attempt was done to survey of literatures for exact solvent extraction to know exact phytocompound and characterization by using instruments along with anticancer properties of these phytochemicals present in fruits and leaves of guava. The compilation of available literatures of last 10 years can be suitable ready references for future experimental study as in vitro and in vivo as well as new drug design as phytomedicines for cancer therapy. Keywords: Bioactive compounds, Psidium guajava, Guava fruits and leaves, Cancer therapy, Phytomedicines


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