The effects of Cernitin® on inflammatory parameters and benign prostatic hyperplasia: An in vitro study

2019 ◽  
Vol 33 (9) ◽  
pp. 2457-2464
Author(s):  
Nishtman Dizeyi ◽  
Ingrid Yao Mattisson ◽  
Lena Ramnemark ◽  
Magnus Grabe ◽  
Per‐Anders Abrahamsson
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
In Vitro Study ◽  
Prostatic Hyperplasia ◽  
Vitro Study ◽  
Inflammatory Parameters

Oxytocin: its role in benign prostatic hyperplasia via the ERK pathway

2017 ◽  
Vol 131 (7) ◽  
pp. 595-607 ◽  
Author(s):  
Huan Xu ◽  
Shi Fu ◽  
Yanbo Chen ◽  
Qi Chen ◽  
Meng Gu ◽  
...  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Cell Signalling ◽  
Animal Experiments ◽  
In Vitro Study ◽  
Treated Group ◽  
Prostatic Hyperplasia ◽  
Prostate Tissue ◽  
Prostate Hyperplasia ◽  
Oxytocin Antagonist

The aim of the present study was to evaluate oxytocin and benign prostatic hyperplasia (BPH), and study the cell signalling mechanism. Investigation was performed in patients about the correlation between oxytocin level and BPH. Mice were injected with oxytocin or oxytocin antagonist for 2 weeks and the prostate morphology was studied after their sacrifice. Furthermore, in vitro experiments were performed to evaluate the oxytocin effect through the MEK/ERK/RSK pathway. Oxytocin was significantly elevated in the serum and prostate tissue of patients with BPH, and a positive correlation with prostate volume indicated. In the animal experiments, prostate enlargement was observed in the oxytocin-treated group, whereas oxytocin antagonist reduced prostate hyperplasia. The in vitro study confirmed this result and also revealed activation of the MEK/ERK/RSK pathway. Oxytocin is highly expressed in the serum and prostate tissue of patients with BPH. In addition, oxytocin aggravates BPH and the oxytocin-induced proliferative effect on prostatic cells is mediated through the MEK/ERK/RSK pathway, at least partly. Thus, the hypothalamic regulation may be involved in development of BPH, which may open a new door to more medications for BPH in the future.

In vitro study of the interaction between human gut microbiota and herbal extracts using willow bark extract as an example

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
EM Pferschy-Wenzig ◽  
K Koskinen ◽  
C Moissl-Eichinger ◽  
R Bauer
Keyword(s):  
Gut Microbiota ◽  
In Vitro Study ◽  
Vitro Study ◽  
Bark Extract ◽  
Herbal Extracts ◽  
Human Gut ◽  
Human Gut Microbiota ◽  
Willow Bark

Evaluation of the Release Behavior of the Dexamethasone Embedded in Polycarbonate Polyurethane Membranes: An In Vitro Study

2003 ◽  
Vol 48 (1) ◽  
pp. 7 ◽  
Author(s):  
Dong Hyun Kim ◽  
Sung Gwon Kang ◽  
Sang Soo Park ◽  
Don Haeng Lee ◽  
Gyu Baek Lee ◽  
...  
Keyword(s):  
In Vitro Study ◽  
Vitro Study ◽  
Release Behavior ◽  
Polyurethane Membranes

Nivel de penetración y microfiltración de sellantes con y sin adhesivos de quinta y sexta generación en premolares. Estudio in vitro

2018 ◽  
Vol 8 (02) ◽  
Author(s):  
Claudia Gabriela Otazú Aldana
Keyword(s):  
In Vitro Study ◽  
Vitro Study ◽  
Sixth Generation

The level of penetration and microleakage of the sealants with or without adhesives of fifth and sixth generation. An in vitro study

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