Effect of Black Tea Consumption on Intracellular Cytokines, Regulatory T Cells and Metabolic Biomarkers in Type 2 Diabetes Patients

2015 ◽  
Vol 30 (3) ◽  
pp. 454-462 ◽  
Author(s):  
Fadia Mahmoud ◽  
David Haines ◽  
Ebaa Al-Ozairi ◽  
Ali Dashti
Keyword(s):  
Type 2 Diabetes ◽  
T Cells ◽  
Regulatory T Cells ◽  
Black Tea ◽  
Tea Consumption ◽  
Intracellular Cytokines ◽  
Metabolic Biomarkers ◽  
Diabetes Patients

305 ASSESSMENT OF REGULATORY T CELLS IN PHENOTYPIC TYPE 2 DIABETES PATIENTS.

2006 ◽  
Vol 54 (1) ◽  
pp. S132.5-S132
Author(s):  
A. Goel ◽  
B. Brooks-Worrell ◽  
J. P. Palmer
Keyword(s):  
Type 2 Diabetes ◽  
T Cells ◽  
Regulatory T Cells ◽  
Diabetes Patients

scholarly journals Attenuation of CD4 + CD25 + Regulatory T Cells in the Tumor Microenvironment by Metformin, a Type 2 Diabetes Drug

EBioMedicine ◽  
2017 ◽  
Vol 25 ◽  
pp. 154-164 ◽  
Author(s):  
Yuki Kunisada ◽  
Shingo Eikawa ◽  
Nahoko Tomonobu ◽  
Shohei Domae ◽  
Takenori Uehara ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
T Cells ◽  
Tumor Microenvironment ◽  
Regulatory T Cells ◽  
Diabetes Drug

scholarly journals Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients

Oncotarget ◽  
2016 ◽  
Vol 7 (10) ◽  
pp. 10976-10989 ◽  
Author(s):  
Huai-Chia Chuang ◽  
Jun-Sing Wang ◽  
I-Te Lee ◽  
Wayne H-H. Sheu ◽  
Tse-Hua Tan
Keyword(s):  
Type 2 Diabetes ◽  
T Cells ◽  
Epigenetic Regulation ◽  
Diabetes Patients

scholarly journals Elevated circulating effector memory T cells but similar levels of regulatory T cells in patients with type 2 diabetes mellitus and cardiovascular disease

2018 ◽  
Vol 16 (3) ◽  
pp. 270-280 ◽  
Author(s):  
Sara Rattik ◽  
Daniel Engelbertsen ◽  
Maria Wigren ◽  
Irena Ljungcrantz ◽  
Gerd Östling ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
T Cells ◽  
Type 2 Diabetes Mellitus ◽  
Regulatory T Cells ◽  
Memory T Cells ◽  
Effector Memory ◽  
Effector Memory T Cells

Type 2 diabetes mellitus is associated with an elevated risk of cardiovascular disease, but the mechanism through which diabetes contributes to cardiovascular disease development remains incompletely understood. In this study, we compared the association of circulating regulatory T cells, naïve T cells, effector memory T cells or central memory T cells with cardiovascular disease in patients with and without type 2 diabetes mellitus. Percentage of circulating T cell subsets was analysed by flow cytometry in type 2 diabetes mellitus subjects with and without prevalent cardiovascular disease as well as in non-diabetic subjects with and without prevalent cardiovascular disease from the Malmö SUMMIT cohort. Subjects with type 2 diabetes mellitus had elevated percentages of effector memory T cells (CD4+CD45RO+CD62L–; 21.8% ± 11.2% vs 17.0% ± 9.2% in non-type 2 diabetes mellitus, p < 0.01) and central memory T cells (CD4+CD45RO+CD62L+; 38.0% ± 10.7% vs 36.0% ± 9.5% in non-type 2 diabetes mellitus, p < 0.01). In contrast, the frequency of naïve T cells was reduced (CD4+CD45RO–CD62L+, 35.0% ± 16.5% vs 42.9% ± 14.4% in non-type 2 diabetes mellitus, p < 0.001). The proportion of effector memory T cells was increased in type 2 diabetes mellitus subjects with cardiovascular disease as compared to those without (26.4% ± 11.5% vs 18.4% ± 10.2%, p < 0.05), while no difference in regulatory T cells was observed between these two patient groups. This study identifies effector memory T cells as a potential cellular biomarker for cardiovascular disease among subjects with type 2 diabetes mellitus, suggesting a state of exacerbated immune activation in type 2 diabetes mellitus patients with cardiovascular disease.

scholarly journals Th17 and regulatory T cells in patients with different time of progression of type 2 diabetes mellitus

2020 ◽  
Vol 45 (1) ◽  
pp. 29-36 ◽  
Author(s):  
Juan Guzmán-Flores ◽  
Joel Ramírez-Emiliano ◽  
Victoriano Pérez-Vázquez ◽  
Sergio López-Briones
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
T Cells ◽  
Type 2 Diabetes Mellitus ◽  
Regulatory T Cells

Effect of Diabetea tea ™ consumption on inflammatory cytokines and metabolic biomarkers in type 2 diabetes patients

2016 ◽  
Vol 194 ◽  
pp. 1069-1077 ◽  
Author(s):  
Fadia Mahmoud ◽  
Ebaa Al-Ozairi ◽  
David Haines ◽  
Ladislav Novotny ◽  
Ali Dashti ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Inflammatory Cytokines ◽  
Metabolic Biomarkers ◽  
Diabetes Patients

scholarly journals Relationship between Th17 and regulatory T cells in patients with type 2 diabetes mellitus

2015 ◽  
Vol 6 ◽  
Author(s):  
Guzman-Flores Juan ◽  
Lopez-Briones Sergio ◽  
Pérez-Vázquez Victoriano ◽  
Ramírez-De Los Santos Saúl ◽  
López-Pulido Edgar
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
T Cells ◽  
Type 2 Diabetes Mellitus ◽  
Regulatory T Cells
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