Antitubercular and Antibacterial Activity of Quinonoid Natural Products Against Multi-Drug Resistant Clinical Isolates

2013 ◽  
Vol 28 (7) ◽  
pp. 1014-1021 ◽  
Author(s):  
Diganta Dey ◽  
Ratnamala Ray ◽  
Banasri Hazra
Keyword(s):  
Antibacterial Activity ◽  
Natural Products ◽  
Clinical Isolates ◽  
Drug Resistant

scholarly journals Antibacterial activity of Taxodium ascendens Diterpenes against Methicillin-resistant Staphylococcus aureus

2014 ◽  
Vol 9 (8) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Courtney M. Starks ◽  
Vanessa L. Norman ◽  
Russell B. Williams ◽  
Matt G. Goering ◽  
Stephanie M. Rice ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Bacterial Infections ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Clinical Isolates ◽  
Drug Resistant ◽  
Methicillin Resistant

One new and seven known diterpenes were identified from an antibacterial chromatographic fraction of Taxodium ascendens. Of these, demethylcryptojaponol (2), 6-hydroxysalvinolone (3), hydroxyferruginol (4), and hinokiol (5) demonstrated potent activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA). These compounds represent a class of synthetically accessible compounds that could be further developed for treatment of drug-resistant bacterial infections.

Antibacterial activity of Indian propolis and its lead compounds against multi-drug resistant clinical isolates

2021 ◽  
pp. 100479
Author(s):  
Vinod S. Nandre ◽  
Aditi V. Bagade ◽  
Deepak M. Kasote ◽  
Jisun H.J. Lee ◽  
Kisan M. Kodam ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Clinical Isolates ◽  
Drug Resistant ◽  
Lead Compounds

scholarly journals Antibaterial activity of the extracts of pineapple and pomelo against five different pathogenic bacterial isolates

2021 ◽  
Vol 11 (1) ◽  
pp. 1-6
Author(s):  
ATM Nahid Hasan ◽  
Trisha Saha ◽  
Tasnia Ahmed
Keyword(s):  
Antibacterial Activity ◽  
Aqueous Extract ◽  
Clinical Isolates ◽  
Ananas Comosus ◽  
Resistant Bacteria ◽  
Drug Resistant ◽  
Methanol Extracts ◽  
Crude Extracts ◽  
Pineapple Peel ◽  
Fruit Samples

To combat the infections caused by antibiotic resistant bacteria, natural candidates are being studied to find out antibacterial activity against the drug-resistant microorganisms. Among the variety of natural candidates of plant origin, many fruits have been proved to have potent antibacterial activity. In the current study, we chose pineapple (Ananas comosus), and pomelo (Citrus maxima) to determine their efficacy against some clinical isolates. Fruit samples were subjected to prepare crude, ethanol, methanol and aqueous extract to determine their antibacterial potency. Clinical isolates were used to determine the antibacterial activity of the extracts against them. The isolates were found to be multi-drug resistant. Out of twenty-eight antibiotics, Pseudomonas aeruginosa was resistant to ten antibiotics and Salmonella spp. was resistant to nine antibiotics. Rather than the crude extracts of the fruits, ethanol and methanol extracts showed antibacterial activity towards multi-drug resistant pathogenic bacteria. Aqueous extract did not show any significant antibacterial activity at all. Extracts of pomelo fruit exhibited the highest results whereas pomelo skin and pineapple peel crude extracts were the least effective compared to the other extracts. Ethanol extract of pineapple fruit (against all isolates but Staphylococcus aureus) and methanol extract of pomelo fruit (against all isolates) showed the lowest MIC (minimum inhibitory concentration) of 187.5 μg/ml. MBC (minimum bactericidal concentration) was found (within the range of 500 μg/ml to 1000 μg/ml) only with ethanol and methanol extracts of pomelo and pineapple. As the clinical isolates were found to be inhibited by the extracts, they can be used as an alternative for treating infections caused by these bacteria. Stamford Journal of Microbiology, Vol.11 (1) 2021: 1-6

scholarly journals Antibacterial activity of Vicoa indica and Tridax procumbens against Multi-Drug Resistant (MDR) clinical isolates

2010 ◽  
Vol 3 (4) ◽  
pp. 163-168
Author(s):  
C.C. Harish ◽  
◽  
A. Safiullah ◽  
R. Shenbagaraman ◽  
V. Shanta Premaraj ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Clinical Isolates ◽  
Drug Resistant ◽  
Tridax Procumbens

scholarly journals In Vitro Antibacterial Activity of Different Honey Samples Against Clinical Isolates

2021 ◽  
Author(s):  
Mahasin Ahmed Wadi
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Bacterial Species ◽  
Antibacterial Properties ◽  
Salmonella Typhi ◽  
Clinical Isolates ◽  
Base Line ◽  
Drug Resistant ◽  
Low Sensitivity

Abstract BackgroundThe emergence of multi–drug resistant organisms has created a lot of clinicalproblems. Hence there is a need to find natural alternative treatment to counter the multi–drug resistant organisms. Honey has a well-established usage as wound dressing in ancient and traditional medicine. The aim of this work is to establish a base-line of the antibacterial activity of 32 natural and commercial various honey samples against 8 clinical isolates.MethodsThirty two honey samples (raw and commercial honey) collected from different countries with different floral origin were tested in vitro for antibacterial activity against 8 clinical isolates collected from patients, at private Hospital from Sudan, using disk diffusion technique. The following 6 Epsilometer test (E Test), Amoxicillin, Augamentin, Ceftaxime, Chloramphenicol, Gentamicin and tetracycline were used against 8 clinical isolates for Minimum Inhibitory Concentration.ResultsThe following 8 clinical isolates were identified by conventional bacteriological methods; Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aerouginosa, Proteus.vulgaris, Salmonella typhi, Shigella sonnei and Methicillin Resistant Staphylococcus aureus (MRSA). Honey has been shown to have antibacterial properties against both Gram-positive and Gram-negative bacteria. The tested organisms showed low sensitivity to antibiotics E test.ConclusionMost of the bacterial species studied were uniformly receptive to all the tested honey. In contrast The tested organisms showed low sensitivity to antibiotics with low MIC.

scholarly journals In vitro antibacterial activity of some antihistaminics belonging to different groups against multi-drug resistant clinical isolates

2011 ◽  
Vol 42 (3) ◽  
pp. 980-991 ◽  
Author(s):  
Moustafa A El-Nakeeb ◽  
Hamida M Abou-Shleib ◽  
Amal M Khalil ◽  
Hoda G Omar ◽  
Omar M El-Halfawy
Keyword(s):  
Antibacterial Activity ◽  
Clinical Isolates ◽  
Drug Resistant ◽  
In Vitro Antibacterial Activity
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