Protective Effect of Brazilian Propolis Against Hepatic Oxidative Damage in Rats with Water-immersion Restraint Stress

2012 ◽  
pp. n/a-n/a ◽  
Author(s):  
Tadashi Nakamura ◽  
Yoshiji Ohta ◽  
Koji Ohashi ◽  
Kumiko Ikeno ◽  
Rie Watanabe ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Protective Effect ◽  
Restraint Stress ◽  
Water Immersion ◽  
Water Immersion Restraint Stress ◽  
Brazilian Propolis

scholarly journals Protective Effect of Repeatedly Preadministered Brazilian Propolis Ethanol Extract against Stress-Induced Gastric Mucosal Lesions in Rats

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Tadashi Nakamura ◽  
Yoshiji Ohta ◽  
Kumiko Ikeno ◽  
Koji Ohashi ◽  
Takeyuki Ikeno
Keyword(s):  
Protective Effect ◽  
Restraint Stress ◽  
Wistar Rats ◽  
Water Immersion ◽  
Ethanol Extract ◽  
Neutrophil Infiltration ◽  
Gastric Mucosal Lesions ◽  
Male Wistar Rats ◽  
Mucosal Lesions ◽  
Brazilian Propolis

The present study was conducted to clarify the protective effect of Brazilian propolis ethanol extract (BPEE) against stress-induced gastric mucosal lesions in rats. The protective effect of BPEE against gastric mucosal lesions in male Wistar rats exposed to water-immersion restraint stress (WIRS) for 6 h was compared between its repeated preadministration (50 mg/kg/day, 7 days) and its single preadministration (50 mg/kg). The repeated BPEE preadministration attenuated WIRS-induced gastric mucosal lesions and gastric mucosal oxidative stress more largely than the single BPEE preadministration. In addition, the repeated BPEE preadministration attenuated neutrophil infiltration in the gastric mucosa of rats exposed to WIRS. The protective effect of the repeated preadministration of BPEE against WIRS-induced gastric mucosal lesions was similar to that of a single preadministration of vitamin E (250 mg/kg) in terms of the extent and manner of protection. From these findings, it is concluded that BPEE preadministered in a repeated manner protects against gastric mucosal lesions in rats exposed to WIRS more effectively than BPEE preadministered in a single manner possibly through its antioxidant and anti-inflammatory actions.

scholarly journals Effect of Dietary Vitamin E Supplementation on Liver Oxidative Damage in Rats with Water-Immersion Restraint Stress

2015 ◽  
Vol 61 (2) ◽  
pp. 113-122 ◽  
Author(s):  
Yoshiji OHTA ◽  
Koji YASHIRO ◽  
Koji OHASHI ◽  
Yosuke HORIKOSHI ◽  
Chiaki KUSUMOTO ◽  
...  
Keyword(s):  
Vitamin E ◽  
Oxidative Damage ◽  
Restraint Stress ◽  
Water Immersion ◽  
Dietary Vitamin ◽  
Water Immersion Restraint Stress ◽  
Vitamin E Supplementation

scholarly journals Vitamin E Depletion Enhances Liver Oxidative Damage in Rats with Water-Immersion Restraint Stress

2013 ◽  
Vol 59 (2) ◽  
pp. 79-86 ◽  
Author(s):  
Yoshiji OHTA ◽  
Koji YASHIRO ◽  
Koji OHASHI ◽  
Yoichiro IMAI ◽  
Chiaki KUSUMOTO ◽  
...  
Keyword(s):  
Vitamin E ◽  
Oxidative Damage ◽  
Restraint Stress ◽  
Water Immersion ◽  
Water Immersion Restraint Stress
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