Hepatoprotective effects of propolis extract on paracetamol-induced liver damage in mice

1994 ◽  
Vol 8 (4) ◽  
pp. 229-232 ◽  
Author(s):  
Ricardo González ◽  
Diadelys Remirez ◽  
Sandra Rodriguez ◽  
Addys González ◽  
Odelsa Ancheta ◽  
...  
Keyword(s):  
Liver Damage ◽  
Propolis Extract ◽  
Hepatoprotective Effects

Hepatoprotective Effects of Allium monanthum MAX. Extract on Ethanol-Induced Liver Damage in Rat

2004 ◽  
Vol 9 (3) ◽  
pp. 245-252 ◽  
Author(s):  
Byun-Suk Choi ◽  
Myung-Yul Lee ◽  
Yoonhwa Jeong ◽  
Gil-Man Shin
Keyword(s):  
Liver Damage ◽  
Hepatoprotective Effects

Hepatoprotective Effects of Hovenia dulcis Fruit on Ethanol-Induced Liver Damage in vitro and in vivo

2009 ◽  
Vol 38 (2) ◽  
pp. 154-159 ◽  
Author(s):  
Yang-Hee You ◽  
Kuk-Yung Jung ◽  
Yoo-Hyun Lee ◽  
Woo-Jin Jun ◽  
Boo-Yong Lee
Keyword(s):  
Liver Damage ◽  
Hepatoprotective Effects ◽  
Hovenia Dulcis

Hepatoprotective effects of dieckol-rich phlorotannins from Ecklonia cava, a brown seaweed, against ethanol induced liver damage in BALB/c mice

2012 ◽  
Vol 50 (6) ◽  
pp. 1986-1991 ◽  
Author(s):  
Min-Cheol Kang ◽  
Ginnae Ahn ◽  
Xiudong Yang ◽  
Kil-Nam Kim ◽  
Sung-Myung Kang ◽  
...  
Keyword(s):  
Liver Damage ◽  
Brown Seaweed ◽  
Ecklonia Cava ◽  
Hepatoprotective Effects

Genoprotective and hepatoprotective effects of Guarana (Paullinia cupanaMart. var.sorbilis) on CCl4-induced liver damage in rats

2015 ◽  
Vol 39 (1) ◽  
pp. 48-52 ◽  
Author(s):  
Helena Kober ◽  
Etiane Tatsch ◽  
Vanessa Dorneles Torbitz ◽  
Lara Peruzzolo Cargnin ◽  
Manuela Borges Sangoi ◽  
...  
Keyword(s):  
Liver Damage ◽  
Hepatoprotective Effects

scholarly journals CHEMICAL COMPOSITION AND HEPATOPROTECTIVE EFFECTS OF POLYPHENOLIC FRACTION FROM RIVEA HYPOCRATERIFORMIS IN PARACETAMOL INDUCED LIVER DAMAGE IN WISTAR ALBINO RATS

2016 ◽  
Vol 8 (10) ◽  
pp. 228
Author(s):  
Shivakumar S. Godipurge ◽  
Naveen J. Biradar ◽  
Jaiprakash S. Biradar ◽  
Nitin Mahurkar
Keyword(s):  
Lipid Peroxidation ◽  
Chemical Composition ◽  
Hydroxyl Radical ◽  
Liver Damage ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity ◽  
Aerial Parts ◽  
Hepatoprotective Effects ◽  
Phenolic And Flavonoid

<p><strong>Objective: </strong>This study was designed to chemical composition and hepatoprotective effects of a polyphenolic fraction of aerial parts of <em>R. hypocrateriformis </em>(PPFRH). It was shown to exhibit strong <em>in vitro</em> lipid peroxidation and scavenging activity against hydroxyl radical.</p><p><strong>Methods: </strong>The chemical composition of a polyphenolic fraction of <em>R. hypocrateriformis</em> was analyzed by High-performance liquid chromatography method. Hepatocellular injuries induced by paracetamol were assessed by liver damage in Wistar albino rat; the hepatoprotective effect was evaluated by biochemical parameters in rat serum, antioxidant hydroxyl radical scavenging activity and lipid peroxidation in liver tissue.</p><p><strong>Results: </strong>The polyphenolic fraction of aerial parts of <em>R. hypocrateriformis</em> for lipid peroxidation is significantly (p&lt;0.05). In the hepatoprotective activity of liver enzymes and hepatic necrosis were significantly (p&lt;0.001) closer to paracetamol. The correlation coefficient between the hydroxyl scavenging radical and total phenolic and flavonoid contents were found to be R² = 0.9045 and R² = 0.8876 suggesting the contribution of phenolic and flavonoid compounds of the polyphenolic fraction of aerial parts of <em>R. hypocrateriformis</em> by 90% and 88% to its radical scavenging activity.</p><p><strong>Conclusion: </strong>The polyphenolic fraction of aerial parts of <em>R. hypocrateriformis</em> possesses a significant protective effect against acute hepatotoxicity induced by paracetamol and which may be due to the phenolic and flavonoid components.</p>

Hepatoprotective Effects of an Anthocyanin Fraction from Purple-Fleshed Sweet Potato Against Acetaminophen-Induced Liver Damage in Mice

2009 ◽  
Vol 12 (2) ◽  
pp. 320-326 ◽  
Author(s):  
Jae Ho Choi ◽  
Chul Yung Choi ◽  
Kyung Jin Lee ◽  
Yong Pil Hwang ◽  
Young Chul Chung ◽  
...  
Keyword(s):  
Sweet Potato ◽  
Liver Damage ◽  
Hepatoprotective Effects

scholarly journals Correlation between Antistress and Hepatoprotective Effects of Schisandra Lignans Was Related with Its Antioxidative Actions in Liver Cells

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Hao-Jie Pu ◽  
Yun-Feng Cao ◽  
Rong-Rong He ◽  
Zhi-Long Zhao ◽  
Jin-Hui Song ◽  
...  
Keyword(s):  
Free Radicals ◽  
Liver Damage ◽  
Restraint Stress ◽  
Liver Cells ◽  
Protective Effects ◽  
Male Mice ◽  
Stress Effects ◽  
Restraint Tube ◽  
Hepatoprotective Effects ◽  
The Relationship

The present study was conducted to investigate the relationship between the anti-stress and hepato-protective effects of Schisandra Lignans Extract (SLE) on stress-induced liver damage. Seven weeks old male mice were fixed in a restraint tube for 18 h to induce liver damage. SLE was orally administered to animals for 5 days at dosages of 100 and 200 mg/kg/day before exposed to restraint stress. Oral administration of SLE significantly reduced restraint-induced liver damage in experimental animal. SLE was further found to significantly alleviate the provocation of corticosterone in stressed mice. SLE also significantly decreased oxidative damage and increased anti-oxidative capability of liver cells by preventing the over production and accumulation of free radicals. In conclusion, the protective effects of SLE on stress-induced liver damage were confirmed, and the correlation between hepatoprotective and anti-stress effects of schisandra lignans was possible related to its alleviation on the malignant effects of stressors for bio-homeostasis, such as balance of oxidation and reduction in cells.

The Hepatoprotective Effects of Taiwan Folk Medicine Ham-Hong-Chho in Rats

1996 ◽  
Vol 24 (03n04) ◽  
pp. 231-240 ◽  
Author(s):  
Hwa-Woei Chih ◽  
Chun-Ching Lin ◽  
Kung-Sheng Tanga
Keyword(s):  
Liver Damage ◽  
Broad Spectrum ◽  
Folk Medicine ◽  
Protective Effects ◽  
Histological Observation ◽  
Bidens Pilosa ◽  
Potential Effectiveness ◽  
Liver Injuries ◽  
Hepatoprotective Effects ◽  
Hepatic Lesions

Bidens pilosa L. var minor (Blume) Sherff, B. pilosa L. and B. chilensis DC (compositae), commonly known as "Ham-hong-chho" in Taiwan, have been traditionally used for medicinal purposes. To clarify and compare the hepatoprotective effects of these three plants, we evaluated their potential effectiveness on CCl4- and acetaminophen-induced acute hepatic lesions in rats. The results indicated that the increase in SGOT and SGPT activities caused by CCl4 (3.0 mI/kg, s.c.) and acetaminophen administration (600 mg/kg, i.p.) could be significantly reduced by treating with the extracts of all the three kinds of "Ham-hong-chho" and the extract of B. chilensis exhibited the greatest hepatoprotective effects. These phenomena were also conflflDed by histological observation. Liver damage induced by CCl4 and acetaminophen was markedly improved in the extract of B. chilensis treated groups, while groups treated with the extracts of B. pilosa var minor and B. pilosa demonstrated only moderate protective effects. The pharmacological and pathological effects of these three crude groups were compared with Bupleurum chinense, which has been reported previously as a treatment criteria in the CCl4 model, and with silymarin as a standard reference medicine in the acetaminophen model. The results suggest that B. pilosa var minor, B. pilosa and B. chilensis can protect liver injuries from various hepatotoxins and have potential as broad spectrum antihepatic agents.

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