Pharmacological activity of a procyanidin isolated fromSclerocarya birrea bark: Antidiarrhoeal activity and effects on isolated guinea-pig ileum

1993 ◽  
Vol 7 (1) ◽  
pp. 25-28 ◽  
Author(s):  
J. Galvez ◽  
M. E. Crespo ◽  
A. Zarzuelo ◽  
P. De Witte ◽  
C. Spiessens
1965 ◽  
Vol 43 (4) ◽  
pp. 657-662 ◽  
Author(s):  
E. A. Hosein ◽  
Teow Yan Koh

The method of parallel bioassay used on the sensitized frog rectus, the dorsal muscle of the leech, the guinea pig ileum, and the cat's blood pressure has been studied to determine whether this method permits the identification of acetylcholine in mixtures of substances which possess acetylcholine-like activity. It was found that the method cannot identify acetylcholine in such mixtures, and in addition, the data obtained indicated that the method also failed to identify other substances with similar pharmacological activity, which were present in the mixtures. It was concluded that the method of parallel bioassay cannot be used to identify acetylcholine in extracts unless it is shown by other means that acetylcholine is the only active substance present in the material being assayed.


Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
WM Shaik Mossadeq ◽  
K Syamimi ◽  
MP Azyyati ◽  
ZA Zakaria ◽  
AK Arifah ◽  
...  

1985 ◽  
Vol 50 (6) ◽  
pp. 1329-1334
Author(s):  
Jaroslav Vičar ◽  
Linda Servítová ◽  
Martin Flegel ◽  
Karel Hauzer ◽  
Tomislav Barth

Analogues of [5-Leu]enkephalin, prolonged by methionine on the N-terminus or, by lysine or methionine on the C-terminus were prepared by fragment condensation, purified by ion exchange chromatography or high-pressure liquid chromatography. The substances were characterised by their opioid activity in a test on guinea-pig ileum in comparison with the activity of [5-Leu]enkephalin.


1998 ◽  
Vol 30 (4-5) ◽  
pp. 242-245 ◽  
Author(s):  
A. V. Glushakov ◽  
H. Yu. Glushakova ◽  
V. I. Skok

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