A cyanobacteria extract and β-carotene stimulate an antitumor host response against an oral cancer cell line

1989 ◽  
Vol 3 (6) ◽  
pp. 243-248 ◽  
Author(s):  
J. L. Schwartz ◽  
G. Shklar
Keyword(s):  
Oral Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Host Response ◽  
Cancer Cell Line ◽  
Oral Cancer Cell ◽  
Oral Cancer Cell Line ◽  
Β Carotene

scholarly journals Ornithine Decarboxylase Antizyme Induces Hypomethylation of Genome DNA and Histone H3 Lysine 9 Dimethylation (H3K9me2) in Human Oral Cancer Cell Line

PLoS ONE ◽  
2010 ◽  
Vol 5 (9) ◽  
pp. e12554 ◽  
Author(s):  
Daisuke Yamamoto ◽  
Kaori Shima ◽  
Kou Matsuo ◽  
Takashi Nishioka ◽  
Chang Yan Chen ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cell Line ◽  
Ornithine Decarboxylase ◽  
Cancer Cell ◽  
Histone H3 ◽  
Cancer Cell Line ◽  
Oral Cancer Cell ◽  
Oral Cancer Cell Line

scholarly journals Dentin Sialophosphoprotein (DSPP) Gene-Silencing Inhibits Key Tumorigenic Activities in Human Oral Cancer Cell Line, OSC2

PLoS ONE ◽  
2010 ◽  
Vol 5 (11) ◽  
pp. e13974 ◽  
Author(s):  
Rajeshree Joshi ◽  
Amany Tawfik ◽  
Nneka Edeh ◽  
Veronica McCloud ◽  
Stephen Looney ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Gene Silencing ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Dentin Sialophosphoprotein ◽  
Oral Cancer Cell ◽  
Oral Cancer Cell Line

scholarly journals 7. Gene transfer using ultrasonic irradiation into the oral cancer cell line

2004 ◽  
Vol 58 (4) ◽  
pp. 125
Author(s):  
Kenjiro Iwanaga ◽  
Kazuhiro Tominaga ◽  
Kozo Yamamoto ◽  
Miho Sukedai ◽  
Toshiyuki Tsujisawa ◽  
...  
Keyword(s):  
Gene Transfer ◽  
Oral Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Ultrasonic Irradiation ◽  
Cancer Cell Line ◽  
Oral Cancer Cell ◽  
Oral Cancer Cell Line

scholarly journals Evaluation and comparison of anti-cancer activity of dapagliflozin and canagliflozin in oral cancer cell line: an in vitro study

2019 ◽  
Vol 8 (3) ◽  
pp. 473 ◽  
Author(s):  
Nenavath Vinay ◽  
Darling Chellathai David
Keyword(s):  
Oral Cancer ◽  
Anticancer Activity ◽  
Cancer Cells ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Sglt2 Inhibitors ◽  
Cytotoxic Assay ◽  
Oral Cancer Cell ◽  
Oral Cancer Cell Line

Background: Cancer is rapidly evolving life-threatening ailment in the mankind due to changes in daily food intake and lifestyle changes. Oral carcinoma is 6th major cause of cancer death in the world and it is third major reason of cancer mortality in India. Every cell in the human body requires glucose for its metabolic energy. Besides normal cell, cancer cells also require the glucose for its endurance and multiplication. SGLT2 inhibitors which are aimed at diabetes therapy exhibited anticancer properties also in colon and pancreatic cancer lines. Present study aim is to evaluate the anticancer activity of SGLT2 inhibitors against oral cancer cell by MTT Assay.Methods: To evaluate the anticancer activity of SGLT2 inhibitors MTT Cytotoxic assay is performed as per standard protocols. Cancer cells were plated in 24-well plates and incubated at 370C with 5% CO2 condition. After convergence, samples are added to the plates in various concentrations and allowed to incubate then they are detached from the plates and cleansed with the reagents. The wells are coated with the dye and incubated. Later samples are analysed in UV-spectrophotometer.Results: Cytotoxic assay showed decrease in cell viability with increasing dose of SGLT2 inhibitors. IC50 values were determined graphically. The IC50 value of dapagliflozin is 400µg/ml and canagliflozin is 250µg/ml respectively after 24 hours of Assessment.Conclusions: The results of the current study give us an evidence that SGLT2 inhibitors dapagliflozin and canagliflozin exhibits anticancer property in Oral Cancer cell line.

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