The efficacy ofSilybum marianum (L.) Gaertn. (silymarin) in the treatment of type II diabetes: a randomized, double-blind, placebo-controlled, clinical trial

2006 ◽  
Vol 20 (12) ◽  
pp. 1036-1039 ◽  
Author(s):  
H. Fallah Huseini ◽  
B. Larijani ◽  
R. Heshmat ◽  
H. Fakhrzadeh ◽  
B. Radjabipour ◽  
...  
2017 ◽  
Vol 22 (4) ◽  
pp. 603-608 ◽  
Author(s):  
Nahid Khalili ◽  
Reza Fereydoonzadeh ◽  
Reza Mohtashami ◽  
Saeed Mehrzadi ◽  
Mojtaba Heydari ◽  
...  

Silybum marianum (L) Gaertn (milk thistle) seeds, Urtica dioica L (nettle) leaves, and Boswellia serrata (olibanum gum) resin are used traditionally by Iranian diabetic patients. The aim of this study was to evaluate the antihyperglycemic effects of these herbs in an herbal formulation in patients with type II diabetes mellitus. Sixty patients diagnosed as type II diabetes mellitus with fasting blood glucose level from 150 to 180 mg/dL, glycosylated hemoglobin level from 7.5% to 8.5%, and on oral antihyperglycemic drugs, were allocated to receive the mix herbal formulation or placebo for 90 days in a double-blind randomized placebo-controlled clinical trial. The mean serum fasting blood glucose, glycosylated hemoglobin, and triglyceride in the herbal drug group were significantly less than placebo group’s values after 3 months of the intervention. The study showed a potential antihyperglycemic and triglyceride lowering effect of the herbal formulation, while it did not have any significant cholesterol or blood pressure lowering effect.


1998 ◽  
Vol 87 (2) ◽  
pp. 86-88
Author(s):  
D P Rastogi ◽  
V P Singh ◽  
Vikram Singh ◽  
S K Dey ◽  
K Rao

2021 ◽  
Vol 97 ◽  
pp. 107715
Author(s):  
Faezeh Abbasirad ◽  
Vahid Shaygannejad ◽  
Fahimeh Hosseininasab ◽  
Omid Mirmosayyeb ◽  
Behzad Mahaki ◽  
...  

2008 ◽  
Vol 103 (1) ◽  
pp. 33-40 ◽  
Author(s):  
Bruno Gualano ◽  
Carlos Ugrinowitsch ◽  
Rafael Batista Novaes ◽  
Guilherme Gianini Artioli ◽  
Maria Heloisa Shimizu ◽  
...  

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