scholarly journals A pragmatic adaptive enrichment design for selecting the right target population for cancer immunotherapies

2020 ◽  
Author(s):  
Anh Nguyen Duc ◽  
Dominik Heinzmann ◽  
Claude Berge ◽  
Marcel Wolbers
Keyword(s):  
Target Population ◽  
The Right ◽  
Cancer Immunotherapies ◽  
Enrichment Design

scholarly journals STAKEHOLDER INVOLVEMENT AND NATURE OF PROCUREMENT PROCESS IN THE UNITED NATIONS ORGANIZATION STABILIZATION MISSION IN THE DEMOCRATIC REPUBLIC OF CONGO (MONUSCO) ENTEBBE SUPPORT BASE

2017 ◽  
Vol 1 (2) ◽  
pp. 55-81
Author(s):  
Gatta Ouyabaka Marius
Keyword(s):  
United Nations ◽  
Democratic Republic Of Congo ◽  
Stakeholder Involvement ◽  
Target Population ◽  
Study Data ◽  
Descriptive Case Study ◽  
Procurement Process ◽  
The Right ◽  
Procurement Planning

Purpose: The purpose of this study was to examine the nature of procurement process followed by MONUSCO and the involvement of stakeholders in this process.Methodology: The study employed a descriptive case study design. The target population comprised of 261 employees of MONUSCO Entebbe Support Base holding international, United Nations Volunteers (UNV) and National contracts. Random and purposive sampling techniques were specifically used to select samples for this study. Data was collected using questionnaires and interview guides. The quantitative data collected was further analysed using SPSS for descriptive and inferential statistics while the qualitative data was analysed using content analysis.Findings: The study findings showed that there is procurement planning in most MONUSCO sections; that funds are available before planning; that staff are involved in procurement planning in their respective sections; and that procurement planning contributes to achieve the maximum value for expenditures on goods/services and works to be delivered at MONUSCO sections. The study found that procurement planning had led to improved levels of MONUSCO operations in the areas of humanitarian relief, peacekeeping, development assistance to affected communities. The study further found that staff are involved in the identification and definition of the needs of user sections and that the Statement of Requirements (SOR)/or Scope of Work (SOW) was important in their respective sections. These had aided in full scale involvement of relevant stakeholders in the procurement planning activities of MONUSCO ESB.Unique contribution to theory, practice and policy: The study recommends a clear determination of specifications in terms of required quality and quantities by the end-user departments in MONUSCO ESB. Planning and determination of needs should be done early to allow enough time to initiate the procurement process. The study further recommends that the procurement department should always engage all concerned stakeholders in determining the materials and service specification for quality assurance during service delivery. This will enable the sections to always get the quantity of items as requested by end-users, in their right quantity, right quality and at the right time.

scholarly journals Management Accounting Techniques and Firm Performance of Major Construction Companies in Nigeria

2021 ◽  
Vol 5 (3) ◽  
pp. 73-93
Author(s):  
Chinomso Asikogu ◽  
◽  
Esther Nkatha M`Ithiria ◽  
John Kebaso Omurwa ◽  
◽  
...  
Keyword(s):  
Firm Performance ◽  
Quantitative Research ◽  
Management Accounting ◽  
Target Population ◽  
Time Frame ◽  
Business Environment ◽  
Strategic Analysis ◽  
Activity Based Costing ◽  
Construction Companies ◽  
The Right

To remain competitive, construction companies must continually improve and one way is by use of the right MATs. The adoption of MATs can help organizations to improve their financial performance continually and consequently overall national economic development. This study investigated influence of management accounting techniques on the firm performance of construction companies in Nigeria. The objectives were, to assess firm performance level of construction companies in Nigeria, to examine the influence of activity-based costing (ABC), strategic analysis, and budgeting practices on firm performance. The study used quantitative research design while the target population was all the 35 major construction firms. The sample size was 13 companies. The research used questionnaire to gather data from 170 managers. The study used descriptive statistics and inferential analysis. The study found that ABC, strategic analysis, and budgeting practices had positive relationship with firm performance. The study concludes that the companies employed ABC to improve firm performance. The study concludes that most companies used both internal and external analysis to improve performance. The study concludes that many companies failed to involve all departments during budgeting. The study recommends that companies should increase resources to complete projects within stipulated time frame. The study recommends that the policies should be enhanced by conducting researches and regular evaluation to improve business environment for the realization of improved performance of the construction companies. Key words: Management Accounting Techniques, Activity-Based Costing, Firm Performance, Strategic Analysis, and Budgeting Practices

scholarly journals The effect of innovation in achieving the competitive advantage  in the industrial companies operating in Hebron governorate: أثر الابتكار في تحقيق الميزة التنافسية في الشركات الصناعية العاملة في محافظة الخليل

2020 ◽  
Vol 4 (5) ◽  
Author(s):  
Adnan A.A. Qubbaja, Nasser ”M.S.”Jaradat
Keyword(s):  
Competitive Advantage ◽  
Analytical Method ◽  
Scientific Research ◽  
Target Population ◽  
Board Members ◽  
Industrial Companies ◽  
Survival And Growth ◽  
The Right ◽  
The Impact ◽  
Purposive Sample

The study aimed at identifying the impact of innovation on achieving the competitive advantage in industrial companies operating in Hebron governorate, the study adopted the descriptive-analytical method for research purposes. The target population consisted of all industrial companies operating in Hebron governorate, Purposive sample of directors, board members, companies directors, heads and directors of departments in industrial companies, ( 80 ) questionnaires were distributed, (70) questionnaires returned for analysis, the study found 82.7% of the variation in competitive advantage is due to innovation in the companies under research, and that the increase of one unit of innovation in the field of the product has led to an increase in competitive advantage by 75.2% of this unit, and that the increase of one unit of innovation in the field of operation has led to An increase in competitive advantage by 83.3% of this unit. The study recommended that companies need to increase attention to the concept of innovation and competitive advantage to promote survival and growth in highly competitive markets, as well as the need to provide the right environment to create innovation and increase the allocation of scientific research by the companies under research.

scholarly journals A shared battle against cancer: overcoming screening uptake differences within European countries

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
L Villani ◽  
M T Riccardi ◽  
A Barbara ◽  
T Sabetta ◽  
M C Nurchis ◽  
...  
Keyword(s):  
National Level ◽  
Target Population ◽  
Population Based ◽  
Screening Programs ◽  
Eu Countries ◽  
Screening Coverage ◽  
Screening Efficiency ◽  
The Mean ◽  
The Right ◽  
Coverage Rates

Abstract Cancer is the second leading cause of dead in Europe and it is responsible of more than 30% of all deaths. For this reason, European Union (EU) identified the battle against cancer as a priority for the European Research Program 2021-2027.About 40% of total deaths for cancers could be prevented with screening.Validated screening test are available for breast (BC), cervical (CC) and colorectal cancers (CRC). In 2003 the Recommendation of the European Council indicated the right timing and the population target but, nowadays, the percentage of screening within EU is low and consistent differences persist among States.In 2020 there are still countries that don't have population-based screening programs. Last data available for all 28 EU countries are referred to 2014. Data were retrieved from “Osservasalute” reports and Global Burden of Disease database.Pearson test and a paired t test were used to describe correlation between mortality and screening coverage rates. In 2014 the mean percentage of screening was 70.7% for CC, 68.7% for BC and 31.3% for CRC and the mean of mortality rate was of 2.1, 10.4 and 17.2 for 100,000, respectively.The rate of mortality did not change significantly in 2017 (2, 10 and 16 for 100,000 respectively).The median coverage is 67 for BC [IR: 43-91], 21.4 for CRC [IR: -3-46] and 70.6 for CC [IR: 54-87]. Pearson test resulted in a negative correlation for all three cancers equal to -0.045, -0.060 and -0.561, respectively.A higher adherence to screening programs is significantly associated to lower mortality rates in all the three types of cancer (p < 0.01). Even if many factors determine the rate of cancer mortality, screening represents the best method to early diagnosis and treatment.Up-to-date data are needed to correctly monitor progress towards the common goal of reaching the entire target population with screenings.A strong leadership at international level is necessary to improve screening programs all over EU and support screening campaigns. Key messages Screening is one of the most efficient and life-saving way to prevent cancer. It is needed to improve screening adherence through population-based programmes both at international and national level. Last data available for all EU countries are referred to 2014. It is necessary to update the data in order to enhance the understanding of screening efficiency.

Trial designs, including observational to interventional

2020 ◽  
pp. 57-64
Author(s):  
Edo Richard
Keyword(s):  
Study Design ◽  
Treatment Effect ◽  
Clinical Relevance ◽  
Observational Studies ◽  
Research Question ◽  
Sample Size Calculation ◽  
Target Population ◽  
Ethical Considerations ◽  
Neuropsychiatric Diseases ◽  
The Right

Observational studies have taught us a lot about the origin of neurological and neuropsychiatric diseases. This chapter describes how we can translate this knowledge into action. Before engaging in a large RCT, several steps have to be taken. First, the potential for a treatment effect has to be compelling. The target population in the RCT has to resemble the population in which observational studies described an association. Second, the outcome of an RCT has to be chosen, and has to have clinical relevance or at least have the potential of clinical relevance in the future. Third, the right study design has to be decided on. Each research question will require a specific study design with accompanying sample size calculation. Lastly, specific ethical considerations have to be taken into account when designing and executing an intervention study. This chapter presents an overview of these issues.

Use of Social Media among Medical Teachers and Students of Punjab, India: A Study

2018 ◽  
Vol 8 (3) ◽  
pp. 1-9
Author(s):  
Shinderpal Kaur ◽  
Rajeev Manhas
Keyword(s):  
Social Media ◽  
Target Population ◽  
Medical College ◽  
Medical Library ◽  
Library Users ◽  
Teachers And Students ◽  
Use Of Social Media ◽  
The Right ◽  
Media Applications ◽  
Medical Colleges

Social media is becoming an inseparable part of modern education system. The present study is an attempt to investigate the awareness, use, purposes and major problems faced while using applications of social media in medical colleges. The data for the present study was collected from the 8 medical colleges of Punjab State of India. A self-designed questionnaire was designed and random sampling method was used to collect the data from the target population i.e. 400 (200 teachers and 200 students with a sample of 25 teachers and 25 students from each medical college i.e. 50X8 = 400). Out of 400 distributed questionnaires, 341 (85.25%) including 146 (73%) teachers and 195 (97.5%) students were received back dully filled in. The results of the present survey show that 69.2% of respondents have average knowledge and awareness of social media. 83.3% use social media applications for educational enhancement purposes. The major problem faced by the respondents is privacy issues with 43.9% responses. The study suggested that library services supplemented by social media applications can prove a great boon to the medical library users in getting the right information at the right time.

STAKEHOLDER INVOLVEMENT AND NATURE OF PROCUREMENT PROCESS IN THE UNITED NATIONS ORGANIZATION STABILIZATION MISSION IN THE DEMOCRATIC REPUBLIC OF CONGO (MONUSCO) ENTEBBE SUPPORT BASE

2017 ◽  
Vol 1 (2) ◽  
pp. 55 ◽  
Author(s):  
Gatta Ouyabaka Marius
Keyword(s):  
United Nations ◽  
Democratic Republic Of Congo ◽  
Stakeholder Involvement ◽  
Target Population ◽  
Study Data ◽  
Descriptive Case Study ◽  
Procurement Process ◽  
The Right ◽  
Procurement Planning

Purpose: The purpose of this study was to examine the nature of procurement process followed by MONUSCO and the involvement of stakeholders in this process.Methodology: The study employed a descriptive case study design. The target population comprised of 261 employees of MONUSCO Entebbe Support Base holding international, United Nations Volunteers (UNV) and National contracts. Random and purposive sampling techniques were specifically used to select samples for this study. Data was collected using questionnaires and interview guides. The quantitative data collected was further analysed using SPSS for descriptive and inferential statistics while the qualitative data was analysed using content analysis.Findings: The study findings showed that there is procurement planning in most MONUSCO sections; that funds are available before planning; that staff are involved in procurement planning in their respective sections; and that procurement planning contributes to achieve the maximum value for expenditures on goods/services and works to be delivered at MONUSCO sections. The study found that procurement planning had led to improved levels of MONUSCO operations in the areas of humanitarian relief, peacekeeping, development assistance to affected communities. The study further found that staff are involved in the identification and definition of the needs of user sections and that the Statement of Requirements (SOR)/or Scope of Work (SOW) was important in their respective sections. These had aided in full scale involvement of relevant stakeholders in the procurement planning activities of MONUSCO ESB.Unique contribution to theory, practice and policy: The study recommends a clear determination of specifications in terms of required quality and quantities by the end-user departments in MONUSCO ESB. Planning and determination of needs should be done early to allow enough time to initiate the procurement process. The study further recommends that the procurement department should always engage all concerned stakeholders in determining the materials and service specification for quality assurance during service delivery. This will enable the sections to always get the quantity of items as requested by end-users, in their right quantity, right quality and at the right time.

scholarly journals COVID-19 case management: The policy model in Morocco context

2020 ◽  
Author(s):  
Issam Bennis
Keyword(s):  
Content Analysis ◽  
Case Management ◽  
Control Strategy ◽  
Scientific Evidence ◽  
Target Population ◽  
Molecular Diagnostic ◽  
Qualitative Model ◽  
Policy Model ◽  
International Knowledge ◽  
The Right

AbstractBackgroundBased on the updated scientific evidence around SARS-CoV-2 diagnostic, health policymakers had to consider that many decisions could enhance or limit the success of the overall COVID-19 control strategy. The purpose of this study is to share alternative COVID-19 case management based on the updated international knowledge.MethodsThis study presents the main information about COVID-19 case management in Morocco from March to October 2020. The NVivo qualitative model content analysis was used to compare and prioritize health decisions with updated scientific evidence.ResultsThe lack of molecular diagnostic accuracy using the interpretation of cycles quantification values, was targeted only by allowing all private laboratories to do RT qPCR. However, there is an urgent need for standardisation with accurate molecular SARS-CoV-2 thermocyclers and kits that notify systematic cycles quantification and do more tests per days to control the spread effectively. A predictive tree of the cycle’s range is presented following three steps: 1) the initial clinical definition, 2) the molecular confirmation, 3) and the diagnostic follows up results of the RT qPCR up to 28 days after the onset. At the same time, the seasonal vaccination against influenza and pneumonia could help to reduce COVID-19 deaths.ConclusionsUntil an available SARS-CoV-2 specific vaccine and/or curative effective treatment, updated control strategy in Morocco and similar context countries require to target population living in highly COVID-19 epidemic cities or areas by mass testing with the right interpretation of PCR values changes, associated to seasonal vaccination to foster the immunity.

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