Quantitative prediction of breast cancer resistant protein (BCRP) mediated drug‐drug interactions using physiologically‐based pharmacokinetic modeling

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12672 ◽

2021 ◽

Author(s):

Chester Costales ◽

Jian Lin ◽

Emi Kimoto ◽

Shinji Yamazaki ◽

James R. Gosset ◽

...

Keyword(s):

Breast Cancer ◽

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Quantitative Prediction ◽

Physiologically Based Pharmacokinetic Modeling ◽

Breast Cancer Resistant Protein ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Quantitative Prediction of Drug–Drug Interactions Involving Inhibitory Metabolites in Drug Development: How Can Physiologically Based Pharmacokinetic Modeling Help?

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12110 ◽

2016 ◽

Vol 5 (10) ◽

pp. 505-515 ◽

Cited By ~ 7

Author(s):

IE Templeton ◽

Y Chen ◽

J Mao ◽

J Lin ◽

H Yu ◽

...

Keyword(s):

Drug Development ◽

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Quantitative Prediction ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Utilizing In Vitro Dissolution-Permeation Chamber for the Quantitative Prediction of pH-Dependent Drug-Drug Interactions with Acid-Reducing Agents: a Comparison with Physiologically Based Pharmacokinetic Modeling

The AAPS Journal ◽

10.1208/s12248-016-9972-4 ◽

2016 ◽

Vol 18 (6) ◽

pp. 1512-1523 ◽

Cited By ~ 11

Author(s):

Andy Z. X. Zhu ◽

Ming-Chih David Ho ◽

Christopher K. Gemski ◽

Bei-Ching Chuang ◽

Mingxiang Liao ◽

...

Keyword(s):

Drug Interactions ◽

Reducing Agents ◽

Pharmacokinetic Modeling ◽

In Vitro Dissolution ◽

Quantitative Prediction ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Ph Dependent

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Physiologically Based Pharmacokinetic Modeling Approach to Predict Drug‐Drug Interactions With Ethionamide Involving Impact of Genetic Polymorphism on FMO3

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1378 ◽

2019 ◽

Vol 59 (6) ◽

pp. 880-889 ◽

Cited By ~ 1

Author(s):

Phuong Thi Thu Nguyen ◽

Md Masud Parvez ◽

Min Jung Kim ◽

Sung Eun Yoo ◽

Sangzin Ahn ◽

...

Keyword(s):

Genetic Polymorphism ◽

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Concomitant use of tamoxifen and endoxifen in postmenopausal early breast cancer: prediction of plasma levels by physiologically-based pharmacokinetic modeling

SpringerPlus ◽

10.1186/2193-1801-3-285 ◽

2014 ◽

Vol 3 (1) ◽

pp. 285 ◽

Cited By ~ 11

Author(s):

Kristin Dickschen ◽

Thomas Eissing ◽

Thomas Mürdter ◽

Matthias Schwab ◽

Stefan Willmann ◽

...

Keyword(s):

Breast Cancer ◽

Early Breast Cancer ◽

Plasma Levels ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Cancer Prediction ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically based pharmacokinetic modeling to predict complex drug-drug interactions: a case study of AZD2327 and its metabolite, competitive and time-dependent CYP3A inhibitors

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.1962 ◽

2015 ◽

Vol 36 (8) ◽

pp. 507-519 ◽

Cited By ~ 4

Author(s):

Jian Guo ◽

Diansong Zhou ◽

Yan Li ◽

Bui H. Khanh

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Time Dependent ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Complex Drug

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Pain Chemogenomics Knowledgebase (Pain-CKB) for Systems Pharmacology Target Mapping and Physiologically Based Pharmacokinetic Modeling Investigation of Opioid Drug–Drug Interactions

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.0c00372 ◽

2020 ◽

Vol 11 (20) ◽

pp. 3245-3258

Author(s):

Mingzhe Shen ◽

Maozi Chen ◽

Tianjian Liang ◽

Siyi Wang ◽

Ying Xue ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Systems Pharmacology ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Implementation of a Physiologically Based Pharmacokinetic Modeling Approach to Guide Optimal Dosing Regimens for Imatinib and Potential Drug Interactions in Paediatrics

Frontiers in Pharmacology ◽

10.3389/fphar.2019.01672 ◽

2020 ◽

Vol 10 ◽

Cited By ~ 2

Author(s):

Jeffry Adiwidjaja ◽

Alan V. Boddy ◽

Andrew J. McLachlan

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Potential Drug ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Optimal Dosing ◽

Physiologically Based ◽

Dosing Regimens

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Physiologically‐Based Pharmacokinetic Modeling for Predicting Drug Interactions of a Combination of Olanzapine and Samidorphan

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12488 ◽

2020 ◽

Vol 9 (2) ◽

pp. 106-114 ◽

Cited By ~ 2

Author(s):

Lei Sun ◽

Lisa Moltke ◽

Karen Rowland Yeo

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically based pharmacokinetic modeling of disposition and drug–drug interactions for atorvastatin and its metabolites

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2015.06.019 ◽

2015 ◽

Vol 77 ◽

pp. 216-229 ◽

Cited By ~ 18

Author(s):

Tao Zhang

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Prediction of Renal Transporter Mediated Drug-Drug Interactions for Pemetrexed Using Physiologically Based Pharmacokinetic Modeling

Drug Metabolism and Disposition ◽

10.1124/dmd.114.059618 ◽

2014 ◽

Vol 43 (3) ◽

pp. 325-334 ◽

Cited By ~ 36

Author(s):

Maria M. Posada ◽

James A. Bacon ◽

Karen B. Schneck ◽

Rommel G. Tirona ◽

Richard B. Kim ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Renal Transporter

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