Design of acid‐activated cell‐penetrating peptides with nuclear localization capacity for anticancer drug delivery

2021 ◽  
Author(s):  
Sujie Huang ◽  
Zhongwen Zhu ◽  
Bo Jia ◽  
Wei Zhang ◽  
Jingjing Song
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Nuclear Localization ◽  
Cell Penetrating Peptides ◽  
Anticancer Drug Delivery ◽  
Cell Penetrating

Accumulation of arginine-rich cell-penetrating peptides in tumors and the potential for anticancer drug delivery in vivo

2012 ◽  
Vol 159 (2) ◽  
pp. 181-188 ◽  
Author(s):  
Ikuhiko Nakase ◽  
Yusuke Konishi ◽  
Masashi Ueda ◽  
Hideo Saji ◽  
Shiroh Futaki
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Cell Penetrating Peptides ◽  
Anticancer Drug Delivery ◽  
Cell Penetrating

Recent developments in anticancer drug delivery using cell penetrating and tumor targeting peptides

2017 ◽  
Vol 250 ◽  
pp. 62-76 ◽  
Author(s):  
Shama Dissanayake ◽  
William A Denny ◽  
Swarna Gamage ◽  
Vijayalekshmi Sarojini
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Tumor Targeting ◽  
Anticancer Drug Delivery ◽  
Cell Penetrating ◽  
Recent Developments

HER2-Mediated Anticancer Drug Delivery: Strategies to Prepare Targeting Ligands Highly Specific for the Receptor

2015 ◽  
Vol 22 (21) ◽  
pp. 2525-2538 ◽  
Author(s):  
Enrica Calce ◽  
Luca Monfregola ◽  
Michele Saviano ◽  
Stefania De Luca
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Anticancer Drug Delivery ◽  
Delivery Strategies

Advances in Nanoparticles as Anticancer Drug Delivery Vector: Need of this Century

2020 ◽  
Vol 26 (15) ◽  
pp. 1637-1649 ◽  
Author(s):  
Imran Ali ◽  
Sofi D. Mukhtar ◽  
Heyam S. Ali ◽  
Marcus T. Scotti ◽  
Luciana Scotti
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Medical Science ◽  
Drug Carriers ◽  
Anticancer Drug Delivery ◽  
Ph Values ◽  
Delivery Vector ◽  
Future Challenges ◽  
Smart Drug ◽  
Smart Drug Delivery

Background: Nanotechnology has contributed a great deal to the field of medical science. Smart drugdelivery vectors, combined with stimuli-based characteristics, are becoming increasingly important. The use of external and internal stimulating factors can have enormous benefits and increase the targeting efficiency of nanotechnology platforms. The pH values of tumor vascular tissues are acidic in nature, allowing the improved targeting of anticancer drug payloads using drug-delivery vectors. Nanopolymers are smart drug-delivery vectors that have recently been developed and recommended for use by scientists because of their potential targeting capabilities, non-toxicity and biocompatibility, and make them ideal nanocarriers for personalized drug delivery. Method: The present review article provides an overview of current advances in the use of nanoparticles (NPs) as anticancer drug-delivery vectors. Results: This article reviews the molecular basis for the use of NPs in medicine, including personalized medicine, personalized therapy, emerging vistas in anticancer therapy, nanopolymer targeting, passive and active targeting transports, pH-responsive drug carriers, biological barriers, computer-aided drug design, future challenges and perspectives, biodegradability and safety. Conclusions: This article will benefit academia, researchers, clinicians, and government authorities by providing a basis for further research advancements.

scholarly journals Biocompatible, surface functionalized mesoporous titania nanoparticles for intracellular imaging and anticancer drug delivery

2011 ◽  
Vol 47 (18) ◽  
pp. 5232 ◽  
Author(s):  
Kevin C.-W. Wu ◽  
Yusuke Yamauchi ◽  
Chen-Yu Hong ◽  
Ya-Huei Yang ◽  
Yung-He Liang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Titania Nanoparticles ◽  
Mesoporous Titania ◽  
Intracellular Imaging ◽  
Anticancer Drug Delivery
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