Structure-activity relationship of a novel pentapeptide with cancer cell growth-inhibitory activity

2010 ◽  
Vol 16 (5) ◽  
pp. 242-248 ◽  
Author(s):  
Masakatsu Kamiya ◽  
Keisuke Oyauchi ◽  
Yoshinori Sato ◽  
Takuya Yokoyama ◽  
Mofei Wang ◽  
...  
Keyword(s):  
Cell Growth ◽  
Cancer Cell ◽  
Inhibitory Activity ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Cancer Cell Growth ◽  
Structure Activity ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity ◽  
Relationship Of

Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity

2010 ◽  
Vol 20 (17) ◽  
pp. 5353-5356 ◽  
Author(s):  
Françoise Borcard ◽  
Matthias Baud ◽  
Claudia Bello ◽  
Giovanna Dal Bello ◽  
Francesco Grossi ◽  
...  
Keyword(s):  
Cell Growth ◽  
Cancer Cell ◽  
Inhibitory Activity ◽  
Cancer Cell Growth ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity

Structure-Activity Relationship of Acetylenes from Galls of Hedera rhombea as Plant Growth Inhibitors

2006 ◽  
Vol 61 (7-8) ◽  
pp. 536-540 ◽  
Author(s):  
Sayumi Yamazoe ◽  
Koji Hasegawa ◽  
Hideyuki Shigemori
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Aliphatic Chain ◽  
Structure Activity ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity ◽  
Almost All ◽  
Relationship Of ◽  
Methylene Group ◽  
Hedera Rhombea

The structure-activity relationship of 12 isolated acetylenes from galls of Hedera rhombea (Araliaceae) induced by Asphondylia sp. (Cecidomyiidae) and their derivatives has been studied for the inhibition of the shoot and root growth of rice, perennial ryegrass, cockscomb, lettuce, and cress. Almost all acetylenes generally showed growth inhibitory activity. The diacetylenes exhibited higher activity than the monoacetylenes, suggesting that a conjugated diyne segment is essential for the activity. On the other hand, the acetylenes with a nonoxidated methylene group at C-8 showed stronger activity comparing with those possessing hydroxy and acetoxy groups at C-8. Furthermore, it has been demonstrated that the acetylenes bearing a terminal olefinic group at C-16,C-17 enhanced the activity. It is thus clarified that important sites for the activity of the acetylenes from galls of H. rhombea are a conjugated diyne and a terminal olefinic group connecting to the aliphatic chain and that less oxidated compounds show more activity.

Design, Synthesis, and Cancer Cell Growth Inhibitory Activity of Triphenylphosphonium Derivatives of the Triterpenoid Betulin

2017 ◽  
Vol 80 (8) ◽  
pp. 2232-2239 ◽  
Author(s):  
Olga V. Tsepaeva ◽  
Andrey V. Nemtarev ◽  
Timur I. Abdullin ◽  
Leysan R. Grigor’eva ◽  
Elena V. Kuznetsova ◽  
...  
Keyword(s):  
Cell Growth ◽  
Cancer Cell ◽  
Inhibitory Activity ◽  
Cancer Cell Growth ◽  
Design Synthesis ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity ◽  
Derivatives Of

Synthesis and cancer cell growth inhibitory activity of icaritin derivatives

2015 ◽  
Vol 100 ◽  
pp. 139-150 ◽  
Author(s):  
Chen Wang ◽  
Ping Wu ◽  
Jing-Fang Shi ◽  
Zi-Hua Jiang ◽  
Xiao-Yi Wei
Keyword(s):  
Cell Growth ◽  
Cancer Cell ◽  
Inhibitory Activity ◽  
Cancer Cell Growth ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity
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