Effects of piperonyl butoxide synergism and cuticular thickening on the contact irritancy response of field Aedes aegypti (Diptera: Culicidae) to deltamethrin

2021 ◽  
Author(s):  
Jin‐Jia Yu ◽  
Lee‐Jin Bong ◽  
Amonrat Panthawong ◽  
Theeraphap Chareonviriyaphap ◽  
Wei‐Ting Liu ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Piperonyl Butoxide

scholarly journals Effects of piperonyl butoxide on the toxicity of the organophosphate temephos and the role of esterases in the insecticide resistance of Aedes aegypti

2014 ◽  
Vol 47 (5) ◽  
pp. 579-582 ◽  
Author(s):  
Boscolli Barbosa Pereira ◽  
Jean Ezequiel Limongi ◽  
Edimar Olegário de Campos Júnior ◽  
Denis Prudencio Luiz ◽  
Warwick Estevam Kerr
Keyword(s):  
Aedes Aegypti ◽  
Insecticide Resistance ◽  
Piperonyl Butoxide

Tests of pyrethroid vaporising mats against Aedes aegypti (L.) (Diptera: Culicidae)

1977 ◽  
Vol 67 (4) ◽  
pp. 667-674 ◽  
Author(s):  
P. R. Chadwick ◽  
C. J. Lord
Keyword(s):  
Aedes Aegypti ◽  
Surface Temperature ◽  
Mineral Oil ◽  
Piperonyl Butoxide ◽  
Electric Heater ◽  
Mosquito Coil

AbstractVaporising mats are used to volatilise small amounts of pyrethroid to prevent mosquito nuisance within houses. A small absorbent mat containing pyrethroid is placed on a 5- to 6-W electric heater. The mat surface temperature is about 125°C. Pyrethroid is released for several hours at a slowly diminishing rate. In tests, no evidence of degradation of bioallethrin was obtained. Vapour from mats inhibited biting by female Aedes aegypti (L.) and caused knockdown and kill. A commercial mat containing 88 mg allethrin was as effective as a mosquito coil containing 0·25% allethrin. In laboratory-made mats, 40 mg bioallethrin or 19 mg S-bioallethrin gave equal or better action than allethrin. Additives, such as piperonyl butoxide, mineral oil or antioxidant slightly reduced the rate of emission of pyrethroid and diminished the bite inhibitory and knockdown effects.

scholarly journals Can piperonyl butoxide enhance the efficacy of pyrethroids against pyrethroid-resistant Aedes aegypti?

2011 ◽  
Vol 16 (4) ◽  
pp. 492-500 ◽  
Author(s):  
Georgina Bingham ◽  
Clare Strode ◽  
Lien Tran ◽  
Pham Thi Khoa ◽  
Helen Pates Jamet
Keyword(s):  
Aedes Aegypti ◽  
Piperonyl Butoxide

Enhanced mortality in deltamethrin-resistant Aedes aegypti in Thailand using a piperonyl butoxide synergist

Acta Tropica ◽  
2019 ◽  
Vol 189 ◽  
pp. 76-83 ◽  
Author(s):  
Monthathip Kongmee ◽  
Kanutcharee Thanispong ◽  
Sunaiyana Sathantriphop ◽  
Chutipong Sukkanon ◽  
Michael J. Bangs ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Piperonyl Butoxide

scholarly journals The pharmacokinetics and drug-drug interactions of ivermectin in Aedes aegypti mosquitoes

2021 ◽  
Vol 17 (3) ◽  
pp. e1009382
Author(s):  
Urs Duthaler ◽  
Michael Weber ◽  
Lorenz Hofer ◽  
Carlos Chaccour ◽  
Marta Maia ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Drug Interactions ◽  
Vector Control ◽  
Elimination Rate ◽  
Control Measures ◽  
Piperonyl Butoxide ◽  
Pharmacokinetic Parameters ◽  
Lag Phase ◽  
Control Female ◽  
Drug Concentrations

Mosquitoes are vectors of major diseases such as dengue fever and malaria. Mass drug administration of endectocides to humans and livestock is a promising complementary approach to current insecticide-based vector control measures. The aim of this study was to establish an insect model for pharmacokinetic and drug-drug interaction studies to develop sustainable endectocides for vector control. FemaleAedes aegyptimosquitoes were fed with human blood containing either ivermectin alone or ivermectin in combination with ketoconazole, rifampicin, ritonavir, or piperonyl butoxide. Drug concentrations were quantified by LC-MS/MS at selected time points post-feeding. Primary pharmacokinetic parameters and extent of drug-drug interactions were calculated by pharmacometric modelling. Lastly, the drug effect of the treatments was examined. The mosquitoes could be dosed with a high precision (%CV: ≤13.4%) over a range of 0.01–1 μg/ml ivermectin without showing saturation (R2: 0.99). The kinetics of ivermectin were characterised by an initial lag phase of 18.5 h (CI90%: 17.0–19.8 h) followed by a slow zero-order elimination rate of 5.5 pg/h (CI90%: 5.1–5.9 pg/h). By contrast, ketoconazole, ritonavir, and piperonyl butoxide were immediately excreted following first order elimination, whereas rifampicin accumulated over days in the mosquitoes. Ritonavir increased the lag phase of ivermectin by 11.4 h (CI90%: 8.7–14.2 h) resulting in an increased exposure (+29%) and an enhanced mosquitocidal effect. In summary, this study shows that the pharmacokinetics of drugs can be investigated and modulated in anAe.aegyptianimal model. This may help in the development of novel vector-control interventions and further our understanding of toxicology in arthropods.

GAMBARAN INDEKS LARVA AEDES AEGYPTI DI BUFFER WILAYAH KERJA BANDARA SEPINGGAN BALIKPAPAN

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Abdurrakhman abdurrakhman Abdurrakhman
Keyword(s):  
Aedes Aegypti ◽  
Buffer Zone ◽  
Chi Square ◽  
Cross Sectional ◽  
Breeding Sites ◽  
Dengue Disease ◽  
Vector Borne Diseases ◽  
Transportation Equipment ◽  
Chi Square Test ◽  
Larvae Density

ABSTRACT : The House index and Container Index in the buffer area of ​​the working area of ​​Balikpapan Sepinggan Airport is still above 1%, so the potential for the spread of dengue disease. Mobilization of people, goods and transportation equipment will increasingly affect the transmission of disease in ports and airports, especially for vector-borne diseases. This study aims to analyze the risk factors associated with larvae density of Aedes aegypti and describe the larvae index in the buffer zone of the Sepinggan Balikpapan Airport This study was a descriptive study with a cross sectional design. The sample in this study was 121 houses with a proportionate stratified random sampling, the research location was in the buffer zone of Sepinggan Balikpapan Airport in November 2018. The variables studied were houses with positive larvae containers, breeding sites and PSN behavior and larvasidation. The data was analyzed using the chi square test. There was a relationship between houses with larvae positive Aedes aegypti, behavior of Mosquito Nest Eradication (PSN) and larvasidation with larvae density of Aedes aegypti but not for breeding sites (p = 0.00 and 95% CI = 0.64), and   (p = 0.00 and 95% CI = 0.34). The description of several Aedes aegypti larvae index, namely House Index (HI) = 57.02%, Container Index (CI) = 24.36%, Bruteau Index (BI) = 148.76, and Flick Free Numbers (ABJ) = 42.98 %. Houses with larvae of Aedes aegypti larvae and PSN and larvasidation behavior were associated with larvae density of Aedes aegypti. The index of HI, CI and BI larvae is of high value so there is a risk of DBD transmission

Detection of dengue virus in Aedes mosquitoes in Delhi, India

ENTOMON ◽  
2019 ◽  
Vol 44 (3) ◽  
pp. 213-218
Author(s):  
Suresh Chand Kaushik ◽  
Sukhvir Singh ◽  
Purnima Srivastava ◽  
R. Rajendran
Keyword(s):  
Early Intervention ◽  
Early Detection ◽  
Aedes Aegypti ◽  
Dengue Virus ◽  
Infection Rate ◽  
Transmission Season ◽  
Aedes Mosquitoes ◽  
Alternative Approach ◽  
Human Sera ◽  
Minimum Infection Rate

Detection of viruses in human sera particularly in endemic areas is cumbersome and laborious. Therefore, an alternative approach, Immuno-fluorescence assay (IFA) was performed to determine dengue virus (DENV) positivity in mosquitoes. A total of 1055 adult Aedes aegypti female mosquitoes were tested for IFA test against DENV. Minimum infection rate (MIR) for DENV was found higher during August to November 2016 ranging from 10.75 to 20.83. The average yearly MIR was about 6.64. Higher MIR for Ae. aegypti was found in Sarfabad, Noida (12.71) and Khoda Colony, Ghaziabad (11.90). Minimum MIR (4.67) was observed in Sanjay colony (Faridabad). The main contribution of this study resides in the development of a more suitable monitoring system for early detection of viral circulation and to prioritize early intervention in the non-transmission season.

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