scholarly journals The stereoisomerism of second generation anticoagulant rodenticides: a way to improve this class of molecules to meet the requirements of society?

2018 ◽  
Vol 75 (4) ◽  
pp. 887-892 ◽  
Author(s):  
Virginie Lattard ◽  
Etienne Benoit
Keyword(s):  
Second Generation ◽  
Anticoagulant Rodenticides

scholarly journals Annual abundance of common Kestrels (Falco tinnunculus) is negatively associated with second generation anticoagulant rodenticides

Ecotoxicology ◽  
2021 ◽  
Vol 30 (4) ◽  
pp. 560-574
Author(s):  
Staffan Roos ◽  
Steve T. Campbell ◽  
Gill Hartley ◽  
Richard F. Shore ◽  
Lee A. Walker ◽  
...  
Keyword(s):  
Land Cover ◽  
Second Generation ◽  
Population Declines ◽  
Falco Tinnunculus ◽  
Negatively Associated ◽  
Land Cover Types ◽  
Anticoagulant Rodenticides ◽  
Potential Population ◽  
The Uk ◽  
Rats And Mice

AbstractRats and mice can damage food and agricultural products as well as transmit diseases, thereby requiring control of their numbers. Application of Second Generation Anticoagulant Rodenticides (SGARs) often reduces rodent numbers locally. However, predators eating rodents, including non-target species, that have consumed SGARs may be secondarily exposed and potentially lethally poisoned. Here we study whether SGARs may have contributed to the widespread population declines of a rodent-eating raptor, the Common Kestrel (Falco tinnunculus) in the UK. We show that 161 (66.8%) of the 241 Kestrels submitted for ecotoxicology tests between 1997 and 2012 had detectable levels of at least one SGAR in their livers. Adult Kestrels had significantly higher prevalence of SGARs than juveniles, suggesting accumulation of SGARs through time. The prevalence and concentrations of individual SGARs in Kestrels were significantly higher in England than in Scotland. SGAR prevalence in Kestrels were positively associated with some land cover types, primarilyarable cerealsandbroad-leaved woodland, and negatively associated with mainlymean elevation, probably reflecting variation in SGAR usage across land cover types. By using volunteer-collected data on national Kestrel abundance 1997–2012, we show that there is a negative correlation between the Kestrel population index in a specific year and the concentration of bromadialone as well as the total SGAR concentration in the same year. Although correlative, this is the first study to provide evidence for a potential population-limiting effect of SGARs on a raptor.

scholarly journals Second generation anticoagulant rodenticides in tawny owls (Strix aluco) from Great Britain

2008 ◽  
Vol 392 (1) ◽  
pp. 93-98 ◽  
Author(s):  
Lee A. Walker ◽  
Anthony Turk ◽  
Sara M. Long ◽  
Claire L. Wienburg ◽  
Jennifer Best ◽  
...  
Keyword(s):  
Great Britain ◽  
Second Generation ◽  
Strix Aluco ◽  
Anticoagulant Rodenticides

scholarly journals Pen and field trials of flupropadine against the house mouse (Mus musculus L.)

1985 ◽  
Vol 95 (2) ◽  
pp. 513-518 ◽  
Author(s):  
F. P. Rowe ◽  
A. Bradfield ◽  
T. Swinney
Keyword(s):  
House Mouse ◽  
Mus Musculus ◽  
Second Generation ◽  
Treatment Success ◽  
Field Trials ◽  
Mortality Data ◽  
Wild Mice ◽  
Anticoagulant Rodenticides ◽  
Farm Buildings ◽  
Family Groups

SUMMARYLaboratory and field trials were conducted to determine the efficacy of the candidate rodenticide flupropadine against the house mouse (Mus musculus L.). In laboratory feeding tests, family groups of wild mice maintained in pens and conditioned to feeding on plain foods were offered flupropadine at either 0·10%, 0·15%, 0·18% or 0·20% in pinhead oatmeal bait. Overall mortalities in replicated 21-day treatments were 66/71 (93·0%), 71/79 (89·9%), 72/70 (94·7%) and 69/75 (92·0%) respectively.In 17 field trials carried out against mice infesting farm buildings, flupropadine was used at 0·10%, 0·15% and 0·18% in oatmeal bait. Mean treatment success, estimated from live-capture and mortality data, was 88·6%, 96·2% and 96·6% respectively.Flupropadine was found to be as near effective against mice as calciferol/warfarin and the second-generation anticoagulant rodenticides difenacoum, bromadiolone and brodifacoum. In further comparison with the anticoagulants, treatment with flupropadine bait achieved markedly quicker control.

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