scholarly journals “LONG COVID”—A hypothesis for understanding the biological basis and pharmacological treatment strategy

2022 ◽  
Vol 10 (1) ◽  
Author(s):  
Bevyn Jarrott ◽  
Richard Head ◽  
Kirsty G. Pringle ◽  
Eugenie R. Lumbers ◽  
Jennifer H. Martin
2019 ◽  
Vol 2 (3) ◽  
pp. 01-09
Author(s):  
Maldonado Sebastian ◽  
Albaca Guadalupe ◽  
Lafuente María Victoria ◽  
Benjamin Monica ◽  
Lopez Jinete Darues ◽  
...  

Junctional ectopic tachycardia (JET) is a rare supraventricular tachycardia more frequently seen in pediatric patients which is associated with high morbidity and mortality without an adequate treatment. Its treatment often requires multiple drugs for arrhythmia control and, in some cases, a cryoablation is indicated. Some patients may revert to sinus rhythm spontaneously after long periods on antiarrhythmic drug. Currently, the arrhythmia prognosis has improved significantly since cryoablation development and the implementation of a more aggressive pharmacological treatment strategy. The purpose of this review is to describe the natural history of idiopathic JET and treatment advances.


2020 ◽  
Vol 395 ◽  
pp. 112839
Author(s):  
Kathleen M. Kantak ◽  
Jamie M. Gauthier ◽  
Elon Mathieson ◽  
Eudokia Knyazhanskaya ◽  
Pedro Rodriguez-Echemendia ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Yoram Barak ◽  
Dov Aizenberg

Weight gain is one of the major drawbacks associated with the pharmacological treatment of schizophrenia. Existing strategies for the prevention and treatment of obesity amongst these patients are disappointing. Switching the current antipsychotic to another that may favorably affect weight is not yet fully established in the psychiatric literature. This meta-analysis focused on switching to aripiprazole as it has a pharmacological and clinical profile that may result in an improved weight control. Nine publications from seven countries worldwide were analyzed. These encompassed 784 schizophrenia and schizoaffective patients, 473 (60%) men and 311 (40%) women, mean age years. The major significant finding was a mean weight reduction by  kgs following the switch to aripiprazole (). Switching to an antipsychotic with a lower propensity to induce weight gain needs be explored as a strategy. Our analysis suggests aripiprazole as a candidate for such a treatment strategy.


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