scholarly journals TKSA-MC: A web server for rational mutation through the optimization of protein charge interactions

2018 ◽  
Vol 86 (11) ◽  
pp. 1184-1188 ◽  
Author(s):  
Vinícius G. Contessoto ◽  
Vinícius M. de Oliveira ◽  
Bruno R. Fernandes ◽  
Gabriel G. Slade ◽  
Vitor B. P. Leite
Keyword(s):  
Web Server ◽  
Protein Charge ◽  
Charge Interactions

scholarly journals TKSA-MC: A Web Server for rational mutation through the optimization of protein charge interactions

2017 ◽  
Author(s):  
Vinícius G. Contessoto ◽  
Vinícius M. de Oliveira ◽  
Bruno R. Fernandes ◽  
Gabriel G. Slade ◽  
Vitor B. P. Leite
Keyword(s):  
Web Server ◽  
Side Chain ◽  
Positive Energy ◽  
State University ◽  
Native State ◽  
Protein Charge ◽  
The Monte Carlo Method ◽  
Free Energy Contribution ◽  
Thermal Stability Of ◽  
Charge Interactions

AbstractThe TKSAMC is a web server which calculates protein charge-charge interactions via the Tanford-Kirkwood Surface Accessibility model with the Monte Carlo method for sampling different protein protonation states. The optimization of charge-charge interactions via directed mutations has successfully enhanced the thermal stability of different proteins and could be a key to protein engineering improvement. The server presents the electrostatic free energy contribution of each polar-charged residue to protein native state stability. The server also indicates which residues contribute to destabilizing the protein native state with positive energy and the side chain exposed to solvent. This residue is a candidate for mutation to increase protein thermostability as a function of the chosen pH condition. The web server is freely available at UNESP (São Paulo State University - DF/IBILCE): http://tksamc.df.ibilce.unesp.br.

Jurnal uji web serber

2020 ◽  
Author(s):  
Wawan saputra
Keyword(s):  
Web Server ◽  
Word Wide Web

Web server adalah tulang belakang dari word wide web(www)

APLIKASI PENCARI INFORMASI PERMINTAAN LAYANAN WEB YANG ERROR MENGGUNAKAN ALGORITMA BOYER-MOORE

2016 ◽  
Vol 1 (1) ◽  
pp. 001
Author(s):  
Harry Setya Hadi
Keyword(s):  
Data Storage ◽  
Computer Network ◽  
Web Server ◽  
Access Methods ◽  
Ip Address ◽  
String Searching ◽  
Common Process ◽  
Web Server Logs ◽  
Different Parts ◽  
The Web

String searching is a common process in the processes that made the computer because the text is the main form of data storage. Boyer-Moore is the search string from right to left is considered the most efficient methods in practice, and matching string from the specified direction specifically an algorithm that has the best results theoretically. A system that is connected to a computer network that literally pick a web server that is accessed by multiple users in different parts of both good and bad aim. Any activity performed by the user, will be stored in Web server logs. With a log report contained in the web server can help a web server administrator to search the web request error. Web server log is a record of the activities of a web site that contains the data associated with the IP address, time of access, the page is opened, activities, and access methods. The amount of data contained in the resulting log is a log shed useful information.

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