scholarly journals High-resolution crystal structures leverage protein binding affinity predictions

2015 ◽  
Vol 84 (1) ◽  
pp. 9-20 ◽  
Author(s):  
Simon Marillet ◽  
Pierre Boudinot ◽  
Frédéric Cazals
Keyword(s):  
High Resolution ◽  
Protein Binding ◽  
Crystal Structures ◽  
Binding Affinity

Crystal Structures of Fragments D and Double-D from Fibrinogen and Fibrin

1999 ◽  
Vol 82 (08) ◽  
pp. 271-276 ◽  
Author(s):  
Glen Spraggon ◽  
Stephen Everse ◽  
Russell Doolittle
Keyword(s):  
Electron Microscopy ◽  
High Resolution ◽  
Crystal Structures ◽  
Structure And Function ◽  
X Ray ◽  
Long Period ◽  
And Function

IntroductionAfter a long period of anticipation,1 the last two years have witnessed the first high-resolution x-ray structures of fragments from fibrinogen and fibrin.2-7 The results confirmed many aspects of fibrinogen structure and function that had previously been inferred from electron microscopy and biochemistry and revealed some unexpected features. Several matters have remained stubbornly unsettled, however, and much more work remains to be done. Here, we review several of the most significant findings that have accompanied the new x-ray structures and discuss some of the problems of the fibrinogen-fibrin conversion that remain unresolved. * Abbreviations: GPR—Gly-Pro-Arg-derivatives; GPRPam—Gly-Pro-Arg-Pro-amide; GHRPam—Gly-His-Arg-Pro-amide

The crystal structures of solvent-free alkali-metal squarates from powder diffraction data

2005 ◽  
Vol 220 (11) ◽  
Author(s):  
Robert E. Dinnebier ◽  
Hanne Nuss ◽  
Martin Jansen
Keyword(s):  
High Resolution ◽  
Alkali Metal ◽  
Crystal Structures ◽  
Powder Diffraction ◽  
Diffraction Data ◽  
Room Temperature ◽  
Solvent Free ◽  
Crystallographic Data ◽  
Powder Diffraction Data ◽  
X Ray

AbstractThe crystal structures of solvent-free lithium, sodium, rubidium, and cesium squarates have been determined from high resolution synchrotron and X-ray laboratory powder patterns. Crystallographic data at room temperature of Li

Ribosomal proteins S5 and L6: high-resolution crystal structures and roles in protein synthesis and antibiotic resistance

1998 ◽  
Vol 279 (4) ◽  
pp. 873-888 ◽  
Author(s):  
Christopher Davies ◽  
Dirksen E Bussiere ◽  
Barbara L Golden ◽  
Stephanie J Porter ◽  
Venki Ramakrishnan ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Antibiotic Resistance ◽  
High Resolution ◽  
Crystal Structures ◽  
Ribosomal Proteins

scholarly journals Learning protein binding affinity using privileged information

2018 ◽  
Vol 19 (1) ◽  
Author(s):  
Wajid Arshad Abbasi ◽  
Amina Asif ◽  
Asa Ben-Hur ◽  
Fayyaz ul Amir Afsar Minhas
Keyword(s):  
Protein Binding ◽  
Binding Affinity ◽  
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