scholarly journals Retraction: Site-specific recombination of nitrogen-fixation genes in cyanobacteria by XisF-XisH-XisI complex: Structures and models, William C. Hwang, James W. Golden, Jaime Pascual, Dong Xu, Anton Cheltsov, Adam Godzik

2018 ◽  
Vol 86 (2) ◽  
pp. 268-268 ◽  
Keyword(s):  
Nitrogen Fixation ◽  
Complex Structures ◽  
Site Specific ◽  
Site Specific Recombination ◽  
Nitrogen Fixation Genes

Genome rearrangements during Anabaena heterocyst differentiation

1988 ◽  
Vol 66 (10) ◽  
pp. 2098-2102 ◽  
Author(s):  
James W. Golden
Keyword(s):  
Nitrogen Fixation ◽  
Filamentous Cyanobacterium ◽  
Coding Region ◽  
Developmentally Regulated ◽  
Site Specific ◽  
Heterocyst Differentiation ◽  
Site Specific Recombination ◽  
Differentiated Cells ◽  
Recombination System ◽  
Cyanobacterium Anabaena

The filamentous cyanobacterium Anabaena sp. PCC 7120 produces specialized, terminally differentiated cells called heterocysts that are the sites of nitrogen fixation. The genome of Anabaena undergoes at least two specific developmentally regulated DNA rearrangements during heterocyst differentiation. One rearrangement involves the nitrogen-fixation genes nifH, nifD, and nifK. During heterocyst differentiation, an 11-kilobase (kb) DNA element is excised from the 3′ coding region of the nifD gene by site-specific recombination within 11 base pair, directly repeated sequences present at the ends of the element. The excision results in formation of a complete nifD coding sequence and allows transcription of all three genes from a single promoter upstream of nifH. The gene xisA, located at one end of the 11-kb element, is believed to encode the site-specific recombinase responsible for excision of the element from the nifD gene. A second DNA rearrangement occurs close to the 5′ end of the nifS gene and results in placing the genes rbcL and rbcS approximately 10 kb from the nif gene cluster. This rearrangement is also a deletion from the chromosome but involves a significantly larger segment of the genome, 55 kb. The genomic breakpoints of the nifS rearrangement have been cloned and sequenced. The recombination sites show no homology to those involved in the nifD rearrangement. This suggests that each rearrangement is catalyzed by a different site-specific recombination system and that the two arrangements may be independently regulated.

Progress on XerCD/dif site-specific recombination

2012 ◽  
Vol 34 (8) ◽  
pp. 1003-1008
Author(s):  
De-Qiao TIAN ◽  
Yu-Min WANG ◽  
Tao ZHENG
Keyword(s):  
Site Specific ◽  
Site Specific Recombination

scholarly journals Xer-mediated site-specific recombination at cer generates Holliday junctions in vivo.

1994 ◽  
Vol 13 (8) ◽  
pp. 1844-1855 ◽  
Author(s):  
R. McCulloch ◽  
L.W. Coggins ◽  
S.D. Colloms ◽  
D.J. Sherratt
Keyword(s):  
Holliday Junctions ◽  
Site Specific ◽  
Site Specific Recombination

Determinants of directionality in lambda site-specific recombination

Cell ◽  
1984 ◽  
Vol 39 (3) ◽  
pp. 699-706 ◽  
Author(s):  
Wade Bushman ◽  
Samuel Yin ◽  
Liu Lin Thio ◽  
Arthur Landy
Keyword(s):  
Site Specific ◽  
Site Specific Recombination
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