Protein side-chain modeling with a protein-dependent optimized rotamer library

2014 ◽  
Vol 82 (9) ◽  
pp. 2000-2017 ◽  
Author(s):  
Patricia Francis-Lyon ◽  
Patrice Koehl
Keyword(s):  
Side Chain ◽  
Rotamer Library

A Study of Phenylalanine Side-Chain Dynamics in Surface-Adsorbed Peptides Using Solid-State Deuterium NMR and Rotamer Library Statistics

2014 ◽  
Vol 136 (32) ◽  
pp. 11402-11411 ◽  
Author(s):  
Kun Li ◽  
Prashant S. Emani ◽  
Jason Ash ◽  
Michael Groves ◽  
Gary P. Drobny
Keyword(s):  
Solid State ◽  
Side Chain ◽  
Deuterium Nmr ◽  
Chain Dynamics ◽  
Rotamer Library ◽  
Side Chain Dynamics

SDRL: a sequence-dependent protein side-chain rotamer library

2015 ◽  
Vol 11 (7) ◽  
pp. 2000-2007 ◽  
Author(s):  
Mohammad Taghizadeh ◽  
Bahram Goliaei ◽  
Armin Madadkar-Sobhani
Keyword(s):  
Amino Acid ◽  
Side Chain ◽  
Side Chains ◽  
Rotamer Library ◽  
Conformational Selection ◽  
Sequence Dependent ◽  
Amino Acid Side Chains ◽  
Dependent Protein ◽  
Selection Of

We established a sequence-dependent rotamer library (SDRL) to help in modeling side chains, better understanding of the conformational selection of amino acid side chains and the search for the neighbor dependency of this conformational selection.

Backbone-dependent Rotamer Library for Proteins Application to Side-chain Prediction

1993 ◽  
Vol 230 (2) ◽  
pp. 543-574 ◽  
Author(s):  
Roland L. Dunbrack ◽  
Martin Karplus
Keyword(s):  
Side Chain ◽  
Rotamer Library

Prediction of protein side-chain rotamers from a backbone-dependent rotamer library: a new homology modeling tool

1997 ◽  
Vol 267 (5) ◽  
pp. 1268-1282 ◽  
Author(s):  
Michael J. Bower ◽  
Fred E. Cohen ◽  
Roland L. Dunbrack
Keyword(s):  
Homology Modeling ◽  
Side Chain ◽  
Modeling Tool ◽  
Rotamer Library

scholarly journals A protein-dependent side-chain rotamer library

2011 ◽  
Vol 12 (S14) ◽  
Author(s):  
Md Shariful Islam Bhuyan ◽  
Xin Gao
Keyword(s):  
Side Chain ◽  
Rotamer Library

Electroluminescent properties of side-chain naphthalimide-derivated polymers

1998 ◽  
Vol 95 (6) ◽  
pp. 1351-1354 ◽  
Author(s):  
C.-M. Bouché ◽  
P. Le Barny ◽  
H. Facoetti ◽  
F. Soyer ◽  
P. Robin
Keyword(s):  
Side Chain

Evidence for Impaired Hepatic Vitamin K1 Metabolism in Patients Treated with N-Methyl-Thiotetrazole Cephalosporins

1984 ◽  
Vol 51 (03) ◽  
pp. 358-361 ◽  
Author(s):  
H Bechtold ◽  
K Andrassy ◽  
E Jähnchen ◽  
J Koderisch ◽  
H Koderisch ◽  
...  
Keyword(s):  
Protein C ◽  
Oral Intake ◽  
Bleeding Complications ◽  
Side Chain ◽  
Acute Administration ◽  
Vitamin K1 ◽  
New Class ◽  
Parenteral Alimentation ◽  
Hepatocellular Regeneration ◽  
Echis Carinatus

SummaryIn 8 patients on no oral intake and with parenteral alimentation, administration of cephalosporins with N-methyl-thiotetrazole side chain (moxalactam, cefamandole), was associated with prolongation of prothrombin time, appearance in the circulation of descarboxy-prothrombin (counter immunoelectrophoresis and echis carinatus assay) and diminution of protein C. Acute administration of 10 mg vitamin Ki was followed by the transient appearance of vitamin K1 2,3-epoxide, indicating an impaired hepatocellular regeneration of vitamin K1 from the epoxide. Impaired hepatic vitamin K1 metabolism, tentatively ascribed to the N-methyl-thiotetrazole group, is one (but possibly not the only) cause of bleeding complications and depression of vitamin K1dependent procoagulants in patients treated with the new class of cephalosporins.

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