Conformational selection and induced changes along the catalytic cycle of Escherichia coli dihydrofolate reductase

2012 ◽  
Vol 80 (10) ◽  
pp. 2369-2383 ◽  
Author(s):  
Thomas R. Weikl ◽  
David D. Boehr
Keyword(s):  
Escherichia Coli ◽  
Dihydrofolate Reductase ◽  
Catalytic Cycle ◽  
Conformational Selection ◽  
Induced Changes

scholarly journals Role of aspartate 27 in the binding of methotrexate to dihydrofolate reductase from Escherichia coli.

1988 ◽  
Vol 263 (19) ◽  
pp. 9187-9198 ◽  
Author(s):  
J R Appleman ◽  
E E Howell ◽  
J Kraut ◽  
M Kühl ◽  
R L Blakley
Keyword(s):  
Escherichia Coli ◽  
Dihydrofolate Reductase

scholarly journals Methotrexate Binding to Dihydrofolate Reductase from a Methotrexate-resistant Strain of Escherichia coli

1973 ◽  
Vol 248 (18) ◽  
pp. 6375-6379
Author(s):  
Myra N. Williams ◽  
Martin Poe ◽  
Norma J. Greenfield ◽  
Jordan M. Hirshfield ◽  
Karst Hoogsteen
Keyword(s):  
Escherichia Coli ◽  
Dihydrofolate Reductase ◽  
Resistant Strain
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