Conserved conformational dynamics of membrane fusion protein transmembrane domains and flanking regions indicated by sequence statistics

2011 ◽  
Vol 79 (8) ◽  
pp. 2418-2427 ◽  
Author(s):  
Sindy Neumann ◽  
Dieter Langosch
Keyword(s):  
Fusion Protein ◽  
Membrane Fusion ◽  
Conformational Dynamics ◽  
Transmembrane Domains ◽  
Membrane Fusion Protein ◽  
Flanking Regions

scholarly journals A membrane fusion protein, Ykt6, regulates epithelial cell migration via microRNA-mediated suppression of Junctional Adhesion Molecule A

Cell Cycle ◽  
2018 ◽  
Vol 17 (14) ◽  
pp. 1812-1831 ◽  
Author(s):  
Nayden G. Naydenov ◽  
Supriya Joshi ◽  
Alex Feygin ◽  
Siddharth Saini ◽  
Larisa Litovchick ◽  
...  
Keyword(s):  
Cell Migration ◽  
Epithelial Cell ◽  
Fusion Protein ◽  
Membrane Fusion ◽  
Adhesion Molecule ◽  
Membrane Fusion Protein ◽  
Epithelial Cell Migration

scholarly journals An effective strategy for recapitulating N-terminal heptad repeat trimers in enveloped virus surface glycoproteins for therapeutic applications

2016 ◽  
Vol 7 (3) ◽  
pp. 2145-2150 ◽  
Author(s):  
Wenqing Lai ◽  
Chao Wang ◽  
Fei Yu ◽  
Lu Lu ◽  
Qian Wang ◽  
...  
Keyword(s):  
Fusion Protein ◽  
Membrane Fusion ◽  
Heptad Repeat ◽  
Effective Strategy ◽  
Virus Surface ◽  
Efficient Strategy ◽  
Therapeutic Applications ◽  
Enveloped Virus ◽  
Membrane Fusion Protein ◽  
Hiv 1

We report an efficient strategy to recapitulate NHR α-helical trimers in the HIV-1 membrane fusion protein as promising antiviral therapeutics.

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