Crystal structure of the cytosolic domain of the cation diffusion facilitator family protein

2009 ◽  
Vol 76 (3) ◽  
pp. 768-771 ◽  
Author(s):  
Takashi Higuchi ◽  
Motoyuki Hattori ◽  
Yoshiki Tanaka ◽  
Ryuichiro Ishitani ◽  
Osamu Nureki
Keyword(s):  
Crystal Structure ◽  
Cation Diffusion ◽  
Cation Diffusion Facilitator ◽  
Family Protein ◽  
Cytosolic Domain ◽  
Cation Diffusion Facilitator Family

scholarly journals The Cation Diffusion Facilitator Family Protein EmfA Confers Resistance to Manganese Toxicity in Brucella abortus 2308 and Is an Essential Virulence Determinant in Mice

2019 ◽  
Vol 202 (1) ◽  
Author(s):  
Matthew J. Johnsrude ◽  
Joshua E. Pitzer ◽  
Daniel W. Martin ◽  
R. Martin Roop
Keyword(s):  
Brucella Abortus ◽  
Manganese Toxicity ◽  
Cation Diffusion ◽  
Cation Diffusion Facilitator ◽  
Mn Toxicity ◽  
Virulence Determinant ◽  
Family Protein ◽  
Cellular Components ◽  
Cation Diffusion Facilitator Family

Mn nutrition is essential for the basic physiology and virulence of Brucella strains. The results of the study presented here demonstrate that the cation diffusion facilitator (CDF)-type metal exporter EmfA plays critical roles in maintaining Mn homeostasis and preventing Mn toxicity in Brucella and is an essential virulence determinant for these bacteria. EmfA and other cellular components involved in Mn homeostasis represent attractive targets for the development of improved vaccines and chemotherapeutic strategies for preventing and treating brucellosis in humans and animals.

ZnT-1 extrudes zinc from mammalian cells functioning as a Zn2+/H+exchanger

Metallomics ◽  
2014 ◽  
Vol 6 (9) ◽  
pp. 1656-1663 ◽  
Author(s):  
Eden Shusterman ◽  
Ofer Beharier ◽  
Levy Shiri ◽  
Raz Zarivach ◽  
Yoram Etzion ◽  
...  
Keyword(s):  
Phylogenetic Tree ◽  
Mammalian Cells ◽  
Cation Diffusion ◽  
Cation Diffusion Facilitator ◽  
Family Protein

ZnT-1 is a Cation Diffusion Facilitator (CDF) family protein, and is present throughout the phylogenetic tree from bacteria to humans.

scholarly journals Mn tolerance in rice is mediated by MTP8.1, a member of the cation diffusion facilitator family

2013 ◽  
Vol 64 (14) ◽  
pp. 4375-4387 ◽  
Author(s):  
Zonghui Chen ◽  
Yumi Fujii ◽  
Naoki Yamaji ◽  
Sakine Masuda ◽  
Yuma Takemoto ◽  
...  
Keyword(s):  
Cation Diffusion ◽  
Cation Diffusion Facilitator ◽  
Cation Diffusion Facilitator Family

scholarly journals Genes Encoding Proteins of the Cation Diffusion Facilitator Family That Confer Manganese Tolerance

2003 ◽  
Vol 15 (5) ◽  
pp. 1131-1142 ◽  
Author(s):  
Emmanuel Delhaize ◽  
Tatsuhiko Kataoka ◽  
Diane M. Hebb ◽  
Rosemary G. White ◽  
Peter R. Ryan
Keyword(s):  
Cation Diffusion ◽  
Cation Diffusion Facilitator ◽  
Manganese Tolerance ◽  
Genes Encoding ◽  
Cation Diffusion Facilitator Family

Characterization of a Glomus intraradices gene encoding a putative Zn transporter of the cation diffusion facilitator family

2005 ◽  
Vol 42 (2) ◽  
pp. 130-140 ◽  
Author(s):  
Manuel González-Guerrero ◽  
Concepción Azcón-Aguilar ◽  
Michelle Mooney ◽  
Ascensión Valderas ◽  
Colin W. MacDiarmid ◽  
...  
Keyword(s):  
Glomus Intraradices ◽  
Cation Diffusion ◽  
Gene Encoding ◽  
Cation Diffusion Facilitator ◽  
Cation Diffusion Facilitator Family
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