Computational proteomics analysis of HIV-1 protease interactome

2007 ◽  
Vol 68 (1) ◽  
pp. 305-312 ◽  
Author(s):  
Aleksejs Kontijevskis ◽  
Jarl E. S. Wikberg ◽  
Jan Komorowski
Keyword(s):  
Proteomics Analysis ◽  
Computational Proteomics ◽  
Hiv 1

scholarly journals Transcriptomics and Targeted Proteomics Analysis to Gain Insights Into the Immune-control Mechanisms of HIV-1 Infected Elite Controllers

EBioMedicine ◽  
2018 ◽  
Vol 27 ◽  
pp. 40-50 ◽  
Author(s):  
Wang Zhang ◽  
Anoop T. Ambikan ◽  
Maike Sperk ◽  
Robert van Domselaar ◽  
Piotr Nowak ◽  
...  
Keyword(s):  
Control Mechanisms ◽  
Targeted Proteomics ◽  
Elite Controllers ◽  
Immune Control ◽  
Proteomics Analysis ◽  
Hiv 1

Ultrastructural observations of human monocytes infected with HIV-1

1991 ◽  
Vol 49 ◽  
pp. 108-109
Author(s):  
James K. Koehler ◽  
Steven G. Reed ◽  
Joao S. Silva
Keyword(s):  
Gradient Centrifugation ◽  
Virus Production ◽  
Human Monocyte ◽  
Red Cross ◽  
Human Monocytes ◽  
Blood Monocytes ◽  
Hiv Replication ◽  
Electron Microscopic ◽  
Ultrastructural Studies ◽  
Hiv 1

As part of a larger study involving the co-infection of human monocyte cultures with HIV and protozoan parasites, electron microscopic observations were made on the course of HIV replication and infection in these cells. Although several ultrastructural studies of the cytopathology associated with HIV infection have appeared, few studies have shown the details of virus production in “normal,” human monocytes/macrophages, one of the natural targets of the virus, and suspected of being a locus of quiescent virus during its long latent period. In this report, we detail some of the interactions of developing virons with the membranes and organelles of the monocyte host.Peripheral blood monocytes were prepared from buffy coats (Portland Red Cross) by Percoll gradient centrifugation, followed by adherence to cover slips. 90-95% pure monocytes were cultured in RPMI with 5% non-activated human AB serum for four days and infected with 100 TCID50/ml of HIV-1 for four hours, washed and incubated in fresh medium for 14 days.

Astrocytic adhesion molecules are increased in HIV-1-associated cognitive/motor complex

1997 ◽  
Vol 23 (3) ◽  
pp. 83-92 ◽  
Author(s):  
D. Seilhean ◽  
A. Dzia-Lepfoundzou ◽  
V. Sazdovitch ◽  
B. Cannella ◽  
C. S. Raine ◽  
...  
Keyword(s):  
Adhesion Molecules ◽  
Motor Complex ◽  
Hiv 1
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