Primary explant culture of human prostate tissue: A model for the study of prostate physiology and pathology

The Prostate ◽  
1990 ◽  
Vol 16 (2) ◽  
pp. 103-126 ◽  
Author(s):  
Donald J. Merchant
Keyword(s):  
Explant Culture ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Human Prostate Tissue ◽  
Primary Explant

Characteristics of nonneoplastic human prostate tissue transplanted into nude mice

The Prostate ◽  
1998 ◽  
Vol 37 (2) ◽  
pp. 109-115 ◽  
Author(s):  
Yasuyuki Yamada ◽  
Keiichi Tozawa ◽  
Lin Cui ◽  
Satoru Takahashi ◽  
Tomoyuki Shirai ◽  
...  
Keyword(s):  
Nude Mice ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Human Prostate Tissue

scholarly journals STIMULATION OF CYCLIC NUCLEOTIDE PRODUCTION ENHANCES THE RELAXATION INDUCED BY PHOSPHODIESTERASE (PDE) INHIBITORS OF ISOLATED HUMAN PROSTATE TISSUE

2009 ◽  
Vol 181 (4S) ◽  
pp. 507-507 ◽  
Author(s):  
Stefan Ückert ◽  
Hamiyet Polat-Yürür ◽  
Friedemann Scheller ◽  
George T. Kedia ◽  
Markus A. Kuczyk
Keyword(s):  
Cyclic Nucleotide ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Pde Inhibitors ◽  
Human Prostate Tissue ◽  
Stimulation Of

LONG TERM ORGAN CULTURE OF HUMAN PROSTATE TISSUE IN A NASA-DESIGNED ROTATING WALL BIOREACTOR

1999 ◽  
Vol 161 (1) ◽  
pp. 290-297 ◽  
Author(s):  
LEONID MARGOLIS ◽  
STEVEN HATFILL ◽  
RODRIGO CHUAQUI ◽  
CATHY VOCKE ◽  
MICHAEL EMMERT-BUCK ◽  
...  
Keyword(s):  
Organ Culture ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Rotating Wall ◽  
Human Prostate Tissue

scholarly journals Numerical simulation modeling of the irreversible electroporation treatment zone for focal therapy of prostate cancer, correlation with whole-mount pathology and T2-weighted MRI sequences

2019 ◽  
Vol 11 ◽  
pp. 175628721985230 ◽  
Author(s):  
Matthijs J. Scheltema ◽  
Tim J. O’Brien ◽  
Willemien van den Bos ◽  
Daniel M. de Bruin ◽  
Rafael V. Davalos ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Irreversible Electroporation ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Ablation Zone ◽  
Electrical Field ◽  
Whole Mount ◽  
Human Prostate Tissue ◽  
Mri Sequences

Background: At present, it is not possible to predict the ablation zone volume following irreversible electroporation (IRE) for prostate cancer (PCa). This study aimed to determine the necessary electrical field threshold to ablate human prostate tissue in vivo with IRE. Methods: In this prospective multicenter trial, patients with localized PCa were treated with IRE 4 weeks before their scheduled radical prostatectomy. In 13 patients, numerical models of the electrical field were generated and compared with the ablation zone volume on whole-mount pathology and T2-weighted magnetic resonance imaging (MRI) sequences. Volume-generating software was used to calculate the ablation zone volumes on histology and MRI. The electric field threshold to ablate prostate tissue was determined for each patient. Results: A total of 13 patients were included for histological and simulation analysis. The median electrical field threshold was 550 V/cm (interquartile range 383–750 V/cm) for the software-generated histology volumes. The median electrical field threshold was 500 V/cm (interquartile range 386–580 V/cm) when the ablation zone volumes were used from the follow-up MRI. Conclusions: The electrical field threshold to ablate human prostate tissue in vivo was determined using whole-mount pathology and MRI. These thresholds may be used to develop treatment planning or monitoring software for IRE prostate ablation; however, further optimization of simulation methods are required to decrease the variance that was observed between patients.

Novel method to characterize immune cells from human prostate tissue

The Prostate ◽  
2014 ◽  
Vol 74 (14) ◽  
pp. 1391-1399 ◽  
Author(s):  
Melissa M. Norström ◽  
Emelie Rådestad ◽  
Arwen Stikvoort ◽  
Lars Egevad ◽  
Mats Bergqvist ◽  
...  
Keyword(s):  
Immune Cells ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Human Prostate Tissue ◽  
Novel Method

Human Prostate Tissue-derived Extracellular Matrix as a Model of Prostate Microenvironment

2016 ◽  
Vol 2 (4) ◽  
pp. 400-408 ◽  
Author(s):  
Walter Cazzaniga ◽  
Manuela Nebuloni ◽  
Erika Longhi ◽  
Irene Locatelli ◽  
Raffaele Allevi ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Human Prostate Tissue
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