MRI‐detectability and histological factors of prostate cancer including intraductal carcinoma and cribriform pattern

The Prostate ◽  
2021 ◽  
Author(s):  
Ayako Mikoshi ◽  
Kosuke Miyai ◽  
Fumiko Hamabe ◽  
Hiromi Edo ◽  
Keiichi Ito ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Intraductal Carcinoma ◽  
Histological Factors

Prostate cancer with cribriform morphology: diagnosis, aggressiveness, molecular pathology and possible relationships with intraductal carcinoma

2018 ◽  
Vol 18 (7) ◽  
pp. 685-693 ◽  
Author(s):  
Rodolfo Montironi ◽  
Alessia Cimadamore ◽  
Silvia Gasparrini ◽  
Roberta Mazzucchelli ◽  
Matteo Santoni ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Molecular Pathology ◽  
Intraductal Carcinoma

The presence and clinical implication of intraductal carcinoma of prostate in metastatic castration resistant prostate cancer

The Prostate ◽  
2015 ◽  
Vol 75 (12) ◽  
pp. 1247-1254 ◽  
Author(s):  
Zhibin Chen ◽  
Ni Chen ◽  
Pengfei Shen ◽  
Jing Gong ◽  
Xiang Li ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Clinical Implication ◽  
Intraductal Carcinoma ◽  
Castration Resistant Prostate Cancer ◽  
Castration Resistant

The presence of intraductal carcinoma of the prostate in needle biopsy as a prognostic parameter for prostate cancer patients with distant metastasis.

2015 ◽  
Vol 33 (7_suppl) ◽  
pp. 237-237
Author(s):  
Masashi Kato ◽  
Toyonori Tsuzuki ◽  
Kyosuke Kimura ◽  
Naoto Sassa ◽  
Yasushi Yoshino ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Patients ◽  
Distant Metastasis ◽  
Needle Biopsy ◽  
Univariate Analysis ◽  
Intraductal Carcinoma ◽  
Prognostic Parameter ◽  
Carcinoma Of The Prostate ◽  
The Core ◽  
Gleason Pattern

237 Background: The presence of intraductal carcinoma of the prostate (IDC-P) is an adverse prognostic factor for prostate-specific antigen (PSA) failure, progression-free survival, and cancer-specific survival (CSS) in localized prostate cancer patients. However, there is no data indicating whether the presence of IDC-P can influence outcome in prostate cancer patients with distant metastasis at presentation. We aimed to evaluate whether IDC-P in needle biopsies is also an adverse prognostic parameter for CSS in prostate cancer patients with distant metastasis. Methods: We retrospectively evaluated 159 prostate cancer patients with distant metastasis who presented at the hospitals that the authors are affiliated with between 2002 and 2012 and reviewed the slides prepared from prostate needle biopsy specimens. Data on the patient age, performance status, clinical T stage, serum PSA, C-reactive protein, alkaline phosphatase (ALP), hemoglobin (Hb), albumin, serum calcium, biopsy Gleason score (> 8 or not), the presence of Gleason pattern 5, the percent of the core involved with cancer, and the maximum percent of a core involved with cancer were analyzed. Patient characteristics were analyzed using the Fisher's exact test. Multivariate Cox proportional hazard regression models were developed to predict CSS. Results: Patient median age was 73 years (range 47–90 years). The median serum PSA was 290 ng/mL (range 4.18–10,992 ng/mL). The median follow-up period was 36 months (range 3–120 months). IDC-P component was detected in 103 (64.8%) patients. There were 82 patients who died of the disease and 6 patients who died of other causes. Using univariate analysis, IDC-P (p = 0.0001), the presence of Gleason pattern 5 (p = 0.005), the percent of the core involved with cancer (p = 0.002), Hb (p = 0.001), and high ALP (p = 0.002) were all shown to be significantly associated with CSS. In the multivariate analysis, only IDC-P (p = 0.016; hazard ratio, 2.187) was significantly associated with CSS. Conclusions: The presence of IDC-P in needle biopsy is a prognostic parameter for CSS in patients with distant metastasis at presentation.

Intraductal carcinoma of the prostate: Precursor or aggressive phenotype of prostate cancer?

The Prostate ◽  
2012 ◽  
Vol 73 (4) ◽  
pp. 442-448 ◽  
Author(s):  
Helmut Bonkhoff ◽  
Thomas M. Wheeler ◽  
Theodorus H. van der Kwast ◽  
Cristina Magi-Galluzzi ◽  
Rodolfo Montironi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Intraductal Carcinoma ◽  
Aggressive Phenotype ◽  
Carcinoma Of The Prostate

1121 INTRADUCTAL CARCINOMA OF THE PROSTATE CAN BE A STRONG PREDICTOR OF PROSTATE CANCER DEATH

2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Masashi Kato ◽  
Kyosuke Kimura ◽  
Toyonori Tsuzuki ◽  
Ryohei Hattori ◽  
Momokazu Gotoh
Keyword(s):  
Prostate Cancer ◽  
Strong Predictor ◽  
Intraductal Carcinoma ◽  
Cancer Death ◽  
Carcinoma Of The Prostate ◽  
Prostate Cancer Death

Prostate cancer outcomes of men with biopsy Gleason score 6 and 7 without cribriform or intraductal carcinoma

2016 ◽  
Vol 15 (13) ◽  
pp. e1650
Author(s):  
C.F. Kweldam ◽  
I.P. Kummerlin ◽  
D. Nieboer ◽  
E.I. Verhoef ◽  
E.W. Steyerberg ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Gleason Score ◽  
Intraductal Carcinoma ◽  
Cancer Outcomes ◽  
Biopsy Gleason Score
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