Impact of five-tiered Gleason grade groups on prognostic prediction in clinical stage T3 prostate cancer undergoing high-dose-rate brachytherapy

The Prostate ◽  
2017 ◽  
Vol 77 (15) ◽  
pp. 1520-1527 ◽  
Author(s):  
Hideyasu Tsumura ◽  
Hiromichi Ishiyama ◽  
Ken-ichi Tabata ◽  
Hiroki Katsumata ◽  
Momoko Kobayashi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Dose Rate ◽  
Clinical Stage ◽  
High Dose Rate ◽  
High Dose ◽  
Gleason Grade ◽  
High Dose Rate Brachytherapy ◽  
Grade Groups ◽  
Prognostic Prediction

High dose rate brachytherapy and external beam radiotherapy for local and locally advanced prostate cancer: Uni-institutional long term results.

2016 ◽  
Vol 34 (2_suppl) ◽  
pp. 319-319
Author(s):  
Antonio Cassio Assis Pellizzon ◽  
Ricardo César Fogaroli ◽  
Maria Leticia GOBO Silva ◽  
Douglas Guedes ◽  
Michael .Chen ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Dose Rate ◽  
Cox Regression ◽  
Clinical Stage ◽  
Locally Advanced ◽  
High Dose Rate ◽  
Long Term Results ◽  
High Dose ◽  
Treatment Combination ◽  
High Dose Rate Brachytherapy

319 Background: Dose-escalation is a determining factor that influences biochemical control (BC) of prostate cancer. High-dose rate brachytherapy (HDR) is one method for providing BC. Methods: Patients with histological diagnosis Gleason scored (GS), clinical stage T1 to T3a, no evidence of metastatic disease, prostate volume > 20cc < 60cc and initial PSA (PSAi) < 60 mg/ml treated from 1997 to 2005 with an Institutional Policy of treatment were evaluated. Results: There were 273 patients treated with this treatment combination at AC Camargo Cancer Center, Sao Paulo, Brazil. The median age and FU time were 64.7 and 10.3 years, respectively. Two hundred thirteen (78.0%) patients had FU longer than 5 years. Actuarial 10-year OS, CSS and BC were 89.8%, 63.6% and 71.8%, respectively. On univariate analyses GS < 7, clinical stage < T2b, low risk group (LR), absence adjuvant androgen deprivation (ADT), age > 65, PSAi < 10, localized EBRT and three dimensional HDR planning were associated with improved CSS and BC. PSAi and age were not favorable associated to BC. Multivariate Cox regression analyses confirmed LR, GS < 7, PSAi < 10, absence of ADT, age < 65 years as predictors of improved CSS and BC. For OS only LR was confirmed as predictive factor. Conclusions: The present data represents a unique single institution study at long FU for the given technique and the comparison with the current literature data confirms the excellent results achieved with this treatment combination.

scholarly journals Salvage high dose rate brachytherapy for recurrent prostate cancer after definitive radiation

2021 ◽  
Author(s):  
Susan Y. Wu ◽  
Anthony C. Wong ◽  
Katsuto Shinohara ◽  
Mack Roach ◽  
J. Adam M. Cunha ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Dose Rate ◽  
High Dose Rate ◽  
High Dose ◽  
Recurrent Prostate Cancer ◽  
High Dose Rate Brachytherapy

scholarly journals High-Dose-Rate Brachytherapy in the Curative Treatment of Patients With Localized Prostate Cancer

2008 ◽  
Vol 83 (12) ◽  
pp. 1364-1372 ◽  
Author(s):  
Thomas M. Pisansky ◽  
Douglas G. Gold ◽  
Keith M. Furutani ◽  
O. Kenneth Macdonald ◽  
Robert H. McLaren ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Dose Rate ◽  
High Dose Rate ◽  
Localized Prostate Cancer ◽  
Curative Treatment ◽  
High Dose ◽  
High Dose Rate Brachytherapy
Sign in / Sign up

Export Citation Format

Share Document