scholarly journals α-Methylacyl-CoA racemase expression and lethal prostate cancer in the Physicians' Health Study and Health Professionals Follow-up Study

The Prostate ◽  
2011 ◽  
Vol 72 (3) ◽  
pp. 301-306 ◽  
Author(s):  
Marc Barry ◽  
Preet K. Dhillon ◽  
Meir J. Stampfer ◽  
Sven Perner ◽  
Jing Ma ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Health Professionals ◽  
Health Study ◽  
Follow Up Study ◽  
Lethal Prostate Cancer

scholarly journals Asthma and risk of lethal prostate cancer in the Health Professionals Follow-Up Study

2015 ◽  
Vol 137 (4) ◽  
pp. 949-958 ◽  
Author(s):  
Elizabeth A. Platz ◽  
Charles G. Drake ◽  
Kathryn M. Wilson ◽  
Siobhan Sutcliffe ◽  
Stacey A. Kenfield ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Health Professionals ◽  
Follow Up Study ◽  
Lethal Prostate Cancer

Aspirin Use and Lethal Prostate Cancer in the Health Professionals Follow-up Study

2019 ◽  
Vol 2 (2) ◽  
pp. 126-134 ◽  
Author(s):  
Mary K. Downer ◽  
Christopher B. Allard ◽  
Mark A. Preston ◽  
Kathryn M. Wilson ◽  
Stacey A. Kenfield ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Health Professionals ◽  
Follow Up Study ◽  
Lethal Prostate Cancer

scholarly journals Alcohol Intake and Risk of Lethal Prostate Cancer in the Health Professionals Follow-Up Study

2019 ◽  
Vol 37 (17) ◽  
pp. 1499-1511 ◽  
Author(s):  
Mary K. Downer ◽  
Stacey A. Kenfield ◽  
Meir J. Stampfer ◽  
Kathryn M. Wilson ◽  
Barbra A. Dickerman ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
At Risk ◽  
Health Professionals ◽  
Lower Risk ◽  
Alcohol Intake ◽  
Red Wine ◽  
Follow Up Study ◽  
Total Alcohol ◽  
Lethal Prostate Cancer

PURPOSE It is unknown whether alcohol intake is associated with the risk of lethal (metastatic or fatal) prostate cancer. We examine (1) whether alcohol intake among men at risk of prostate cancer is associated with diagnosis of lethal prostate cancer and (2) whether intake among men with nonmetastatic prostate cancer is associated with metastasis or death. METHODS This prospective cohort study uses the Health Professionals Follow-Up Study (1986 to 2012). Our analysis of alcohol intake among men at risk of prostate cancer included 47,568 cancer-free men. Our analysis of alcohol intake among men with prostate cancer was restricted to 5,182 men diagnosed with nonmetastatic prostate cancer during follow-up. We examine the association of total alcohol, red and white wine, beer, and liquor with lethal prostate cancer and death. Multivariate Cox proportional hazards regression estimated hazard ratios (HRs) and 95% CIs. RESULTS Alcohol drinkers had a lower risk of lethal prostate cancer (any v none: HR, 0.84 [95% CI, 0.71 to 0.99]) without a dose-response relationship. Total alcohol intake among patients with prostate cancer was not associated with progression to lethal prostate cancer (any v none: HR, 0.99 [95% CI, 0.57 to 1.72]), whereas moderate red wine intake was associated with a lower risk (any v none: HR, 0.50 [95% CI, 0.29 to 0.86]; P trend = .05). Compared with none, 15 to 30 g/d of total alcohol after prostate cancer diagnosis was associated with a lower risk of death (HR, 0.71 [95% CI, 0.50 to 1.00]), as was red wine (any v none: HR, 0.74 [95% CI, 0.57 to 0.97]; P trend = .007). CONCLUSION Cancer-free men who consumed alcohol had a slightly lower risk of lethal prostate cancer compared with abstainers. Among men with prostate cancer, red wine was associated with a lower risk of progression to lethal disease. These observed associations merit additional study but provide assurance that moderate alcohol consumption is safe for patients with prostate cancer.

scholarly journals Postdiagnostic Statin Use and the Risk of Lethal Prostate Cancer in the Health Professionals Follow-up Study

2015 ◽  
Vol 24 (10) ◽  
pp. 1638-1640 ◽  
Author(s):  
June M. Chan ◽  
Stacey A. Kenfield ◽  
Alan Paciorek ◽  
Elizabeth A. Platz ◽  
Edward L. Giovannucci ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Health Professionals ◽  
Follow Up Study ◽  
Statin Use ◽  
Lethal Prostate Cancer

scholarly journals A Prospective Analysis of Meat Mutagens and Colorectal Cancer in the Nurses’ Health Study and Health Professionals Follow-up Study

2016 ◽  
Vol 124 (10) ◽  
pp. 1529-1536 ◽  
Author(s):  
Ngoan Tran Le ◽  
Fernanda Alessandra Silva Michels ◽  
Mingyang Song ◽  
Xuehong Zhang ◽  
Adam M. Bernstein ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Health Professionals ◽  
Health Study ◽  
Prospective Analysis ◽  
Follow Up Study
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