Nevirapine restores androgen signaling in hormone-refractory human prostate carcinoma cells both in vitro and in vivo

The Prostate ◽  
2009 ◽  
Vol 69 (7) ◽  
pp. 744-754 ◽  
Author(s):  
Matteo Landriscina ◽  
Cinzia Bagalà ◽  
Annamaria Piscazzi ◽  
Giovanni Schinzari ◽  
Michela Quirino ◽  
...  
Keyword(s):  
Prostate Carcinoma ◽  
Carcinoma Cells ◽  
Human Prostate ◽  
Human Prostate Carcinoma ◽  
Hormone Refractory

Erratum: Nevirapine restores androgen signaling in hormone-refractory human prostate carcinoma cells both in vitro and in vivo

The Prostate ◽  
2009 ◽  
Vol 69 (12) ◽  
pp. 1368-1368 ◽  
Author(s):  
Matteo Landriscina ◽  
Cinzia Bagalà ◽  
Annamaria Piscazzi ◽  
Giovanni Schinzari ◽  
Michela Quirino ◽  
...  
Keyword(s):  
Prostate Carcinoma ◽  
Carcinoma Cells ◽  
Human Prostate ◽  
Human Prostate Carcinoma ◽  
Hormone Refractory

scholarly journals Tubeimoside-1 induces oxidative stress-mediated apoptosis and G0/G1 phase arrest in human prostate carcinoma cells in vitro

2016 ◽  
Vol 37 (7) ◽  
pp. 950-962 ◽  
Author(s):  
Jing-bo Yang ◽  
Muhammad Khan ◽  
Yang-yang He ◽  
Min Yao ◽  
Yong-ming Li ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Prostate Carcinoma ◽  
Carcinoma Cells ◽  
Human Prostate ◽  
G1 Phase ◽  
Phase Arrest ◽  
G1 Phase Arrest ◽  
Human Prostate Carcinoma

EGF receptor signaling enhances in vivo invasiveness of DU-145 human prostate carcinoma cells

1996 ◽  
Vol 14 (4) ◽  
pp. 409-418 ◽  
Author(s):  
Timothy Turnert ◽  
Philip Chen ◽  
Lyndon J. Goodly ◽  
Alan NWells
Keyword(s):  
Prostate Carcinoma ◽  
Egf Receptor ◽  
Carcinoma Cells ◽  
Human Prostate ◽  
Receptor Signaling ◽  
Human Prostate Carcinoma

scholarly journals Migration and Invasion Enhancer 1 Is an NF-ĸB-Inducing Gene Enhancing the Cell Proliferation and Invasion Ability of Human Prostate Carcinoma Cells In Vitro and In Vivo

Cancers ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 1486 ◽  
Author(s):  
Chang ◽  
Tsui ◽  
Lin ◽  
Hou ◽  
Feng ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Prostate Carcinoma ◽  
Immunohistochemical Analysis ◽  
Carcinoma Cells ◽  
Human Prostate ◽  
Migration And Invasion ◽  
Akt Inhibitor ◽  
Gene Expressions

: Migration and invasion enhancer 1 (MIEN1) is a membrane-anchored protein and exists in various cancerous tissues. However, the roles of MIEN1 in prostate cancer have not yet been clearly addressed. We determined the expression, biological functions, and regulatory mechanisms of MIEN1 in the prostate. The results of immunohistochemical analysis indicated that MIEN1 was expressed specifically in epithelial cells and significantly higher in adenocarcinoma as compared to in normal tissues. MIEN1 enhanced in vitro cell proliferation, invasion, and in vivo tumorigenesis. Meanwhile, MIEN1 attenuated cisplatin-induced apoptosis in PC-3 cells. Overexpression of NF-ĸB-inducing kinase (NIK) enhanced MIEN1 expression, while overexpression of NF-ĸB inhibitor α (IĸBα) blocked MIEN1 expression in PC-3 cells. In prostate carcinoma cells, MIEN1 provoked Akt phosphorylation; moreover, MIEN1 downregulated N-myc downstream regulated 1 (NDRG1) but upregulated interleukin-6 (IL-6) gene expression. MK2206, an Akt inhibitor, impeded the modulation of MIEN1 on NDRG1 and IL-6 expressions. Our studies suggest that MIEN1 is an NF-ĸB downstream oncogene in the human prostate. Accordingly, the modulation of Akt signaling in the gene expressions of NDRG1 and IL-6 may account for the functions of MIEN1 in cell proliferation, invasion, and tumorigenesis in prostate carcinoma cells.

Cyclooxygenase-2 Inhibitor NS398 Enhances Antitumor Effect of Irradiation on Hormone Refractory Human Prostate Carcinoma Cells

2003 ◽  
Vol 170 (5) ◽  
pp. 2036-2039 ◽  
Author(s):  
BIXIU WEN ◽  
ERIC DEUTSCH ◽  
PASCAL ESCHWEGE ◽  
RENAUD DE CREVOISIER ◽  
ELIE NASR ◽  
...  
Keyword(s):  
Prostate Carcinoma ◽  
Antitumor Effect ◽  
Cyclooxygenase 2 ◽  
Carcinoma Cells ◽  
Human Prostate ◽  
Human Prostate Carcinoma ◽  
Hormone Refractory

In vitro invasiveness of DU-145 human prostate carcinoma cells is modulated by EGF receptor-mediated signals

1995 ◽  
Vol 13 (6) ◽  
pp. 407-419 ◽  
Author(s):  
Heng Xie ◽  
Timothy Turner ◽  
Ming-Hui Wang ◽  
Raj K. Singh ◽  
Gene P. Siegal ◽  
...  
Keyword(s):  
Prostate Carcinoma ◽  
Egf Receptor ◽  
Carcinoma Cells ◽  
Human Prostate ◽  
Human Prostate Carcinoma ◽  
In Vitro Invasiveness
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