scholarly journals PI3K/Akt-dependent transcriptional regulation and activation of BMP-2-Smad signaling by NF-κB in metastatic prostate cancer cells

The Prostate ◽  
2009 ◽  
Vol 69 (2) ◽  
pp. 168-180 ◽  
Author(s):  
Tisheeka R. Graham ◽  
Valerie A. Odero-Marah ◽  
Leland W. Chung ◽  
Krishna C. Agrawal ◽  
Rodney Davis ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Transcriptional Regulation ◽  
Cancer Cells ◽  
Metastatic Prostate Cancer ◽  
Prostate Cancer Cells ◽  
Smad Signaling

Transcriptional regulation of the homeobox geneNKX3.1 by all-trans retinoic acid in prostate cancer cells

2006 ◽  
Vol 99 (5) ◽  
pp. 1409-1419 ◽  
Author(s):  
Marc A. Thomas ◽  
Myles C. Hodgson ◽  
Susan D. Loermans ◽  
Joel Hooper ◽  
Raelene Endersby ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Transcriptional Regulation ◽  
Retinoic Acid ◽  
Cancer Cells ◽  
Prostate Cancer Cells ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid

scholarly journals RNA sequencing reveals upregulation of a transcriptomic program associated with stemness in metastatic prostate cancer cells selected for taxane resistance

Oncotarget ◽  
2018 ◽  
Vol 9 (54) ◽  
pp. 30363-30384 ◽  
Author(s):  
Christina K. Cajigas-Du Ross ◽  
Shannalee R. Martinez ◽  
Leanne Woods-Burnham ◽  
Alfonso M. Durán ◽  
Sourav Roy ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Rna Sequencing ◽  
Metastatic Prostate Cancer ◽  
Prostate Cancer Cells ◽  
Taxane Resistance

scholarly journals Cysteine (C)-X-C Receptor 4 Undergoes Transportin 1-Dependent Nuclear Localization and Remains Functional at the Nucleus of Metastatic Prostate Cancer Cells

PLoS ONE ◽  
2013 ◽  
Vol 8 (2) ◽  
pp. e57194 ◽  
Author(s):  
Ayesha S. Don-Salu-Hewage ◽  
Siu Yuen Chan ◽  
Kathleen M. McAndrews ◽  
Mahandranauth A. Chetram ◽  
Michelle R. Dawson ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Nuclear Localization ◽  
Metastatic Prostate Cancer ◽  
Prostate Cancer Cells

scholarly journals Oncogenic Properties of NEAT1 in Prostate Cancer Cells Depend on the CDC5L–AGRN Transcriptional Regulation Circuit

2018 ◽  
Vol 78 (15) ◽  
pp. 4138-4149 ◽  
Author(s):  
Xin Li ◽  
Xianteng Wang ◽  
Wanlu Song ◽  
Hui Xu ◽  
Rongyao Huang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Transcriptional Regulation ◽  
Cancer Cells ◽  
Prostate Cancer Cells

An in vitro model of prostate cancer bone metastasis for highly metastatic and non-metastatic prostate cancer using nanoclay bone-mimetic scaffolds

MRS Advances ◽  
2019 ◽  
Vol 4 (21) ◽  
pp. 1207-1213 ◽  
Author(s):  
MD Shahjahan Molla ◽  
Dinesh R. Katti ◽  
Kalpana S. Katti
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Metastatic Prostate Cancer ◽  
Cancer Metastasis ◽  
Human Mesenchymal Stem Cells ◽  
Culture Technique ◽  
Complex Nature ◽  
Bone Microenvironment ◽  
Prostate Cancer Cells

ABSTRACTProstate cancer has a strong preference for metastasizing to bone which is the primary cause of prostate cancer-related morbidity and mortality. The complex nature of cancer metastasis requires the development of translational models that recapitulate a specific metastatic stage. Herein, we report the mimicking of mesenchymal to epithelial transition (MET) of prostate cancer cells using highly metastatic and a non-metastatic prostate cancer cell lines. A unique cell culture technique that we termed as ‘sequential culture’ was used to create a biomimetic bone microenvironment for metastasized prostate cancer cells by introducing bioactive factors from osteogenic induction of human mesenchymal stem cells (MSCs) within the porous 3D scaffolds. The in vitro 3D tumor model can be used as a testbed to study the interaction between prostate cancer and bone microenvironment and for the design of novel therapeutic studies.

Membrane Fluidity, Invasiveness and Dynamic Phenotype of Metastatic Prostate Cancer Cells after Treatment with Soy Isoflavones

2013 ◽  
Vol 246 (4) ◽  
pp. 307-314 ◽  
Author(s):  
Vladimir Ajdžanović ◽  
Marija Mojić ◽  
Danijela Maksimović-Ivanić ◽  
Mirna Bulatović ◽  
Sanja Mijatović ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Membrane Fluidity ◽  
Metastatic Prostate Cancer ◽  
Soy Isoflavones ◽  
Prostate Cancer Cells
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