Genome-wide scan for linkage in finnish hereditary prostate cancer (HPC) families identifies novel susceptibility loci at 11q14 and 3p25-26

The Prostate ◽  
2003 ◽  
Vol 57 (4) ◽  
pp. 280-289 ◽  
Author(s):  
Johanna Schleutker ◽  
Agnes B. Baffoe-Bonnie ◽  
Elizabeth Gillanders ◽  
Tommi Kainu ◽  
Mary-Pat Jones ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Susceptibility Loci ◽  
Hereditary Prostate Cancer ◽  
Genome Wide ◽  
Genome Wide Scan

Genome-wide scan for prostate cancer susceptibility genes in the Johns Hopkins hereditary prostate cancer families

The Prostate ◽  
2003 ◽  
Vol 57 (4) ◽  
pp. 320-325 ◽  
Author(s):  
Jianfeng Xu ◽  
Elizabeth M. Gillanders ◽  
Sarah D. Isaacs ◽  
Bao-li Chang ◽  
Kathy E. Wiley ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Susceptibility ◽  
Susceptibility Genes ◽  
Hereditary Prostate Cancer ◽  
Cancer Susceptibility Genes ◽  
Prostate Cancer Susceptibility ◽  
Genome Wide ◽  
Genome Wide Scan

Novel region of interest in chromosome 11 and other putative regions identified in a genome-wide scan in finnish hereditary prostate cancer families

2002 ◽  
Vol 1 (1) ◽  
pp. 8
Author(s):  
Mika Matikainen ◽  
Johanna Schleutker ◽  
Elizabeth Gillanders ◽  
Agnes Baffoe-Bonnie ◽  
Mary Pat Jones ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Region Of Interest ◽  
Chromosome 11 ◽  
Hereditary Prostate Cancer ◽  
Genome Wide ◽  
A Genome ◽  
Genome Wide Scan

Genome-wide scan of Swedish families with hereditary prostate cancer: Suggestive evidence of linkage at 5q11.2 and 19p13.3

The Prostate ◽  
2003 ◽  
Vol 57 (4) ◽  
pp. 290-297 ◽  
Author(s):  
Fredrik Wiklund ◽  
Elizabeth M. Gillanders ◽  
Julie A. Albertus ◽  
Anders Bergh ◽  
Jan-Erik Damber ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Hereditary Prostate Cancer ◽  
Suggestive Evidence ◽  
Genome Wide ◽  
Genome Wide Scan

Genome-wide linkage of 77 families from the African American Hereditary Prostate Cancer Study (AAHPC)

The Prostate ◽  
2006 ◽  
Vol 67 (1) ◽  
pp. 22-31 ◽  
Author(s):  
Agnes B. Baffoe-Bonnie ◽  
Rick A. Kittles ◽  
Elizabeth Gillanders ◽  
Liang Ou ◽  
Asha George ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
African American ◽  
Cancer Study ◽  
Hereditary Prostate Cancer ◽  
Genome Wide ◽  
Prostate Cancer Study

A genome-wide scan for schizophrenia and psychosis susceptibility loci in families of Mexican and Central American ancestry

2007 ◽  
Vol 144B (2) ◽  
pp. 193-199 ◽  
Author(s):  
M.A. Escamilla ◽  
A. Ontiveros ◽  
H. Nicolini ◽  
H. Raventos ◽  
R. Mendoza ◽  
...  
Keyword(s):  
Central American ◽  
Susceptibility Loci ◽  
Genome Wide ◽  
A Genome ◽  
Genome Wide Scan

Age-related maculopathy: an expanded genome-wide scan with evidence of susceptibility loci within the 1q31 and 17q25 regions

2001 ◽  
Vol 132 (5) ◽  
pp. 682-692 ◽  
Author(s):  
Daniel E Weeks ◽  
Yvette P Conley ◽  
Hui-ju Tsai ◽  
Tammy S Mah ◽  
Philip J Rosenfeld ◽  
...  
Keyword(s):  
Susceptibility Loci ◽  
Age Related ◽  
Genome Wide ◽  
Genome Wide Scan

scholarly journals 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Ryo Takata ◽  
Atsushi Takahashi ◽  
Masashi Fujita ◽  
Yukihide Momozawa ◽  
Edward J. Saunders ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Japanese Population ◽  
Genome Wide Association Study ◽  
Association Studies ◽  
European Population ◽  
Genome Wide Association ◽  
High Risk Population ◽  
Genome Wide Association Studies ◽  
Susceptibility Loci ◽  
Genome Wide

Abstract Genome-wide association studies (GWAS) have identified ~170 genetic loci associated with prostate cancer (PCa) risk, but most of them were identified in European populations. We here performed a GWAS and replication study using a large Japanese cohort (9,906 cases and 83,943 male controls) to identify novel susceptibility loci associated with PCa risk. We found 12 novel loci for PCa including rs1125927 (TMEM17, P = 3.95 × 10−16), rs73862213 (GATA2, P = 5.87 × 10−23), rs77911174 (ZMIZ1, P = 5.28 × 10−20), and rs138708 (SUN2, P = 1.13 × 10−15), seven of which had crucially low minor allele frequency in European population. Furthermore, we stratified the polygenic risk for Japanese PCa patients by using 82 SNPs, which were significantly associated with Japanese PCa risk in our study, and found that early onset cases and cases with family history of PCa were enriched in the genetically high-risk population. Our study provides important insight into genetic mechanisms of PCa and facilitates PCa risk stratification in Japanese population.

scholarly journals Genome-wide Scan Identifies Role for AOX1 in Prostate Cancer Survival

2018 ◽  
Vol 74 (6) ◽  
pp. 710-719 ◽  
Author(s):  
Weiqiang Li ◽  
Mridu Middha ◽  
Mesude Bicak ◽  
Daniel D. Sjoberg ◽  
Emily Vertosick ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Survival ◽  
Genome Wide ◽  
Genome Wide Scan
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