scholarly journals NMR reveals novel mechanisms of protein activity regulation

2011 ◽  
Vol 20 (5) ◽  
pp. 773-782 ◽  
Author(s):  
Charalampos G. Kalodimos
Keyword(s):  
Activity Regulation ◽  
Protein Activity

Protein activity regulation by conformational entropy

Nature ◽  
2012 ◽  
Vol 488 (7410) ◽  
pp. 236-240 ◽  
Author(s):  
Shiou-Ru Tzeng ◽  
Charalampos G. Kalodimos
Keyword(s):  
Activity Regulation ◽  
Conformational Entropy ◽  
Protein Activity

Protein Activity Regulation: Inhibition by Closed-Loop Aptamer-Based Structures and Restoration by Near-IR Stimulation

2015 ◽  
Vol 137 (33) ◽  
pp. 10576-10584 ◽  
Author(s):  
Jie Wang ◽  
Yurong Wei ◽  
Xiaoxia Hu ◽  
Yu-Yan Fang ◽  
Xinyang Li ◽  
...  
Keyword(s):  
Closed Loop ◽  
Activity Regulation ◽  
Protein Activity ◽  
Near Ir

Biodegradation of organophosphorus Pollutants by Soil Bacteria: Biochemical Aspects and Unsolved Problems

2020 ◽  
Vol 36 (4) ◽  
pp. 126-135
Author(s):  
T.V. Shushkova ◽  
D.O. Epiktetov ◽  
S.V. Tarlachkov ◽  
I.T. Ermakova ◽  
A.A. Leontievskii
Keyword(s):  
Genome Sequencing ◽  
Soil Bacteria ◽  
Activity Regulation ◽  
Bacterial Isolates ◽  
Bacterial Strains ◽  
Russian Science ◽  
Degrading Bacteria ◽  
Phosphorus Source ◽  
Glyphosate Herbicide ◽  
Enzymatic Pathways

The degradation of persistent organophosphorus pollutants have been studied in 6 soil bacterial isolates and in 3 bacterial strains adapted for utilization of glyphosate herbicide (GP) under laboratory conditions. Significant differences in the uptake of organophosphonates were found in taxonomically close strains possessing similar enzymatic pathways of catabolism of these compounds, which indicates the existence of unknown mechanisms of activity regulation of these enzymes. The effect of adaptation for GP utilization as a sole phosphorus source on assimilation rates of several other phosphonates was observed in studied bacteria. The newly found efficient stains provided up to 56% of GP decomposition after application to the soil in the laboratory. The unresolved problems of microbial GP metabolism and the trends for further research on the creation of reliable biologicals capable of decomposing organophosphonates in the environment are discussed. organophosphonates, glyphosate, biodegradation, bioremediation, C-P lyase, phosphonatase, degrading bacteria Investigation of phosphonatase and genome sequencing were supported by Russian Science Foundation Grant no. 18-074-00021.

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