scholarly journals Covariation of residues in the homeodomain sequence family

1995 ◽  
Vol 4 (11) ◽  
pp. 2269-2278 ◽  
Author(s):  
Neil D. Clarke
Keyword(s):  
Sequence Family ◽  
Homeodomain Sequence

scholarly journals Variants within the yeast Ty sequence family encode a class of structurally conserved proteins

1985 ◽  
Vol 13 (11) ◽  
pp. 4097-4112 ◽  
Author(s):  
Alexandra M. Fulton ◽  
Jane Mellor ◽  
Melanie J. Dobson ◽  
John Chester ◽  
John R. Warmington ◽  
...  
Keyword(s):  
Sequence Family

XlHbox 8: a novel Xenopus homeo protein restricted to a narrow band of endoderm

Development ◽  
1989 ◽  
Vol 105 (4) ◽  
pp. 787-794 ◽  
Author(s):  
C.V. Wright ◽  
P. Schnegelsberg ◽  
E.M. De Robertis
Keyword(s):  
Nuclear Protein ◽  
Narrow Band ◽  
Homeobox Gene ◽  
Positional Information ◽  
Temporal Expression ◽  
Factors Affecting ◽  
New Class ◽  
Homeodomain Sequence ◽  
Pancreatic Epithelium ◽  
Endodermal Differentiation

We report the isolation of a new homeobox gene from Xenopus laevis genomic DNA. The homeodomain sequence is highly diverged from the prototype Antennapedia sequence, and contains a unique histidine residue in the helix that binds to DNA. The homeodomain is followed by a 65 amino acid carboxyterminal domain, the longest found to date in any vertebrate homeobox gene. We have raised specific antibodies against an XlHbox 8-beta-gal fusion protein to determine the spatial and temporal expression of this gene. The nuclear protein first appears in a narrow band of the endoderm at stage 33 and develops into expression within the epithelial cells of the pancreatic anlagen and duodenum. Expression within the pancreatic epithelium persists into the adult frog. This unprecedented restriction to an anteroposterior band of the endoderm suggests that vertebrate homeobox genes might be involved in specifying positional information not only in the neuroectoderm and mesoderm, but also in the endoderm. Our data suggest that XlHbox 8 may therefore represent the first member of a new class of position-dependent transcription factors affecting endodermal differentiation.

Fast Generation of Bent Sequence Family

2010 ◽  
Vol 9 (7) ◽  
pp. 1397-1402 ◽  
Author(s):  
Fangfang Chen ◽  
Jingyu Hua ◽  
Cheng Zhao ◽  
Shouli Zhou
Keyword(s):  
Sequence Family

Organization of the micronuclear genome of oxytricha nova.

Genetics ◽  
1988 ◽  
Vol 120 (1) ◽  
pp. 123-134
Author(s):  
C L Jahn ◽  
K E Prescott ◽  
M W Waggener
Keyword(s):  
Repetitive Dna ◽  
Repetitive Sequence ◽  
Repetitive Element ◽  
Repetitive Sequences ◽  
Unique Sequence ◽  
Sequence Family ◽  
Consensus Map ◽  
Ciliated Protozoan ◽  
Oxytricha Nova ◽  
First Time

Abstract In the hypotrichous ciliated protozoan Oxytricha nova, approximately 95% of the micronuclear genome, including all of the repetitive DNA and most of the unique sequence DNA, is eliminated during the formation of the macronuclear genome. We have examined the interspersion patterns of repetitive and unique and eliminated and retained sequences in the micronuclear genome by characterizing randomly selected clones of micronuclear DNA. Three major classes of clones have been defined: (1) those containing primarily unique, retained sequences; (2) those containing only unique, eliminated sequences; and (3) those containing only repetitive, eliminated sequences. Clones of type one and three document two aspects of organization observed previously: clustering of macronuclear destined sequences and the presence of a prevalent repetitive element. Clones of the second type demonstrate for the first time that eliminated unique sequence DNA occurs in long stretches uninterrupted by repetitive sequences. To further examine repetitive sequence interspersion, we characterized the repetitive sequence family that is present in 50% of the clones (class three above). A consensus map of this element was obtained by mapping approximately 80 phage clones and by hybridization to digests of micronuclear DNA. The repeat element is extremely large (approximately 24 kb) and is interspersed with both macronuclear destined sequences and eliminated unique sequences.

scholarly journals The XLR sequence family: dispersion on the X and Y chromosomes of a large set of closely related sequences, most of which are pseudogenes

1989 ◽  
Vol 17 (23) ◽  
pp. 9871-9888 ◽  
Author(s):  
Henri-Jean Garchon ◽  
Elwyn Loh ◽  
William Y. Ho ◽  
Laurence Amar ◽  
Philip Avner ◽  
...  
Keyword(s):  
Large Set ◽  
Sequence Family ◽  
Y Chromosomes
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