Biochemical Investigation of an N ‐acetyltransferase from Helicobacter pullorum

2021 ◽  
Author(s):  
William A. Griffiths ◽  
Keelan D. Spencer ◽  
James B. Thoden ◽  
Hazel M. Holden
Keyword(s):  
Biochemical Investigation

Biochemical investigation of 3‐sulfopropionaldehyde reductase HpfD

ChemBioChem ◽  
2021 ◽  
Author(s):  
Yan Zhang ◽  
Junwei An ◽  
Yifeng Wei ◽  
Jiayi Liu ◽  
Ee Lui Ang ◽  
...  
Keyword(s):  
Biochemical Investigation

Characterization and biochemical investigation of the potential inositol monophosphate phosphatase involved in bacterial mycothiol biosynthesis

2018 ◽  
Vol 37 (9) ◽  
pp. 507-521 ◽  
Author(s):  
Yuchuan Guo ◽  
Wei Gong ◽  
Lizhen Wang ◽  
Jiatong Guo ◽  
Guoxia Jin ◽  
...  
Keyword(s):  
Biochemical Investigation

scholarly journals The T4:TBG Ratio: A Re-Evaluation with Particular Reference to Low and High Serum TBG Levels

1982 ◽  
Vol 19 (2) ◽  
pp. 101-103 ◽  
Author(s):  
E C Attwood ◽  
G E Atkin
Keyword(s):  
Retrospective Study ◽  
Thyroid Function ◽  
Reference Range ◽  
High Serum ◽  
Reference Ranges ◽  
Thyroid Function Tests ◽  
Thyroxine Binding Globulin ◽  
Biochemical Investigation ◽  
Small Increments ◽  
Routine Assay

The thyroxine: thyroxine-binding globulin (T4: TBG) ratio is now an established part of the biochemical investigation of thyroid function. Reference ranges have been reported for euthyroid subjects with TBG levels within the range 6–16 mg/l. Routine assay of TBG on all thyroid function tests in this laboratory has suggested that, in patients with low or high TBG levels, the established reference ranges for T4:TBG may not be strictly applicable. A retrospective study has been made of a large number of thyroid function requests, including serum total T4, free T4, TBG, and TSH assays. Evidence is presented to show that in subjects with a TBG level of less than 8 mg/l the reference range for T4: TBG is elevated. Similarly, in subjects with a TBG greater than 16 mg/l, the reference range for T4: TBG is lowered. The data suggest that it is necessary to quote a T4: TBG reference range based on small increments of TBG levels or to relate total T4 reference ranges to those increments.

A morphometric and biochemical investigation of the vesiculation of kidney microvilli

1976 ◽  
Vol 21 (3) ◽  
pp. 449-463
Author(s):  
A.G. Booth ◽  
J. Kenny
Keyword(s):  
Proximal Tubule ◽  
Internal Structure ◽  
Mercuric Chloride ◽  
Actin Filaments ◽  
Temperature Dependent ◽  
Tissue Slices ◽  
Osmotic Swelling ◽  
Biochemical Investigation ◽  
Brush Borders ◽  
Cross Bridges

The vesiculation of kidney proximal tubule microvilli has been examined in tissue slices, isolated brush borders and isolated microvilli. Vesiculation could be induced in tissue slices by 2,4-dinitrophenol and anoxia. Cycloheximide and fluoride had no effect. In brush borders and microvilli, the vesiculation was found to be essentially temperature-dependent. Whilst an osmotic swelling could be produced by hypo-osmolar media, the temperature-dependent vesiculation could not be prevented in hyper-osmolar media. Of a wide variety of reagents tested, only glutaraldehyde, mercuric chloride and mersalyl were effective in arresting the vesiculation. Electron micrographs show that vesiculation involves a collapse of the internal structure of the microvillus. However, the collapse was not associated with depolymerization of the microvillus actin filaments. Rather it appeared to be due to the parting of cross-bridges between the membrane and the actin filaments. The nature of these cross-bridges is discussed: it is suggested that alpha-actinin possesses the characteristics for the cross-bridging protein and that vesiculation might be explained by the displacement of alpha-actinin by tropomyosin.

Synthesis and biochemical investigation of scyphostatin analogues as inhibitors of neutral sphingomyelinase

2001 ◽  
Vol 9 (11) ◽  
pp. 2901-2904 ◽  
Author(s):  
Christoph Arenz ◽  
Michael Gartner ◽  
Veit Wascholowski ◽  
Athanassios Giannis
Keyword(s):  
Neutral Sphingomyelinase ◽  
Biochemical Investigation

Biochemical investigation of leukocyte functions during lithium therapy

1993 ◽  
Vol 25 (10) ◽  
pp. 1501-1504 ◽  
Author(s):  
Nurten Türközkan ◽  
Osman Durmus ◽  
Nuri Boran
Keyword(s):  
Lithium Therapy ◽  
Biochemical Investigation
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