An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of α1
-antitrypsin upon ligand binding

Mun Peak Nyon; Tanya Prentice; Jemma Day; John Kirkpatrick; Ganesh N. Sivalingam; Geraldine Levy; Imran Haq; James A. Irving; David A. Lomas; John Christodoulou; Bibek Gooptu; Konstantinos Thalassinos

doi:10.1002/pro.2706

An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of α1 -antitrypsin upon ligand binding

Protein Science ◽

10.1002/pro.2706 ◽

2015 ◽

Vol 24 (8) ◽

pp. 1301-1312 ◽

Cited By ~ 24

Author(s):

Mun Peak Nyon ◽

Tanya Prentice ◽

Jemma Day ◽

John Kirkpatrick ◽

Ganesh N. Sivalingam ◽

...

Keyword(s):

Mass Spectrometry ◽

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Ion Mobility ◽

Conformational Dynamics ◽

Integrative Approach ◽

Resonance Spectroscopy ◽

Ion Mobility Mass Spectrometry ◽

X Ray ◽

X Ray Crystallography

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Travelling wave ion mobility mass spectrometry studies of protein structure: biological significance and comparison with X-ray crystallography and nuclear magnetic resonance spectroscopy measurements

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3737 ◽

2008 ◽

Vol 22 (20) ◽

pp. 3297-3304 ◽

Cited By ~ 133

Author(s):

Charlotte A. Scarff ◽

Konstantinos Thalassinos ◽

Gillian R. Hilton ◽

James H. Scrivens

Keyword(s):

Mass Spectrometry ◽

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Ion Mobility ◽

Biological Significance ◽

Travelling Wave ◽

Resonance Spectroscopy ◽

Ion Mobility Mass Spectrometry ◽

X Ray ◽

X Ray Crystallography

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Synthesis and characterisation of [N(PPh3)2][RuRh5(CO)16] by X-ray crystallography and by natural-abundance carbon-13 nuclear magnetic resonance spectroscopy

Journal of the Chemical Society Dalton Transactions ◽

10.1039/dt9870000781 ◽

1987 ◽

pp. 781 ◽

Cited By ~ 11

Author(s):

Jouni Pursiainen ◽

Tapani A. Pakkanen ◽

Kimmo Smolander

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Magnetic Resonance Spectroscopy ◽

Nuclear Magnetic Resonance Spectroscopy ◽

Natural Abundance ◽

Resonance Spectroscopy ◽

X Ray ◽

X Ray Crystallography ◽

Nuclear Magnetic

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A study on the structures of 3-methoxycarbonylrifamycins by X-ray crystallography and 1H nuclear magnetic resonance spectroscopy

Journal of the Chemical Society Perkin Transactions 2 ◽

10.1039/p29820001633 ◽

1982 ◽

pp. 1633 ◽

Cited By ~ 3

Author(s):

Luciano Cellai ◽

Silvio Cerrini ◽

Annalaura Segre ◽

Mario Brufani ◽

Walter Fedeli ◽

...

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Magnetic Resonance Spectroscopy ◽

Nuclear Magnetic Resonance Spectroscopy ◽

Resonance Spectroscopy ◽

X Ray ◽

X Ray Crystallography ◽

1H Nuclear Magnetic Resonance ◽

Nuclear Magnetic

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Heterocyclic rearrangements. Part VI. Structure and stereochemistry of a sulphur-bridged tetrahydroazepine and derived sulphoxides, by X-ray crystallography and nuclear magnetic resonance spectroscopy

Journal of the Chemical Society Perkin Transactions 1 ◽

10.1039/p19720000357 ◽

1972 ◽

pp. 357 ◽

Cited By ~ 1

Author(s):

Ulli Eisner ◽

M. Z. Haq ◽

J. Flippen ◽

I. Karle

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Magnetic Resonance Spectroscopy ◽

Nuclear Magnetic Resonance Spectroscopy ◽

Resonance Spectroscopy ◽

X Ray ◽

X Ray Crystallography ◽

Nuclear Magnetic

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Study of the structure of besulpamide, 1-[(4-chloro-3-sulfamoylbenzoyl)amino]2,4,6-trimethylpyridinium hydroxide inner salt, and related compounds, using X-Ray crystallography and1H and13C nuclear magnetic resonance spectroscopy

Journal of Heterocyclic Chemistry ◽

10.1002/jhet.5570260527 ◽

1989 ◽

Vol 26 (5) ◽

pp. 1373-1382 ◽

Cited By ~ 3

Author(s):

Jordi Frigola

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Magnetic Resonance Spectroscopy ◽

Nuclear Magnetic Resonance Spectroscopy ◽

Resonance Spectroscopy ◽

X Ray ◽

X Ray Crystallography ◽

Related Compounds ◽

Nuclear Magnetic

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ChemInform Abstract: Synthesis and Characterisation of (N(PPh3)2)(RuRh5(CO)16) by X-Ray Crystallography and by Natural-Abundance Carbon-13 Nuclear Magnetic Resonance Spectroscopy.

ChemInform ◽

10.1002/chin.198731292 ◽

1987 ◽

Vol 18 (31) ◽

Author(s):

J. PURSIAINEN ◽

T. A. PAKKANEN ◽

K. SMOLANDER

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Magnetic Resonance Spectroscopy ◽

Nuclear Magnetic Resonance Spectroscopy ◽

Natural Abundance ◽

Resonance Spectroscopy ◽

X Ray ◽

X Ray Crystallography ◽

Nuclear Magnetic

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Study of the structure of Droxicam, 5-methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide, using X-ray crystallography and 1H and 13C nuclear magnetic resonance spectroscopy

Journal of the Chemical Society Perkin Transactions 2 ◽

10.1039/p29880000241 ◽

1988 ◽

pp. 241 ◽

Cited By ~ 8

Author(s):

Jordi Frigola

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Magnetic Resonance Spectroscopy ◽

Nuclear Magnetic Resonance Spectroscopy ◽

Resonance Spectroscopy ◽

X Ray ◽

X Ray Crystallography ◽

13C Nuclear Magnetic Resonance ◽

Nuclear Magnetic

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Structural investigations of 3-acylpyrrolidine-2,4-diones by nuclear magnetic resonance spectroscopy and X-ray crystallography

Journal of the Chemical Society Perkin Transactions 1 ◽

10.1039/p19800001057 ◽

1980 ◽

pp. 1057 ◽

Cited By ~ 69

Author(s):

Magnet J. Nolte ◽

Pieter S. Steyn ◽

Philippus L. Wessels

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Magnetic Resonance Spectroscopy ◽

Nuclear Magnetic Resonance Spectroscopy ◽

Resonance Spectroscopy ◽

Structural Investigations ◽

X Ray ◽

X Ray Crystallography ◽

Nuclear Magnetic

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ChemInform Abstract: STRUCTURAL INVESTIGATIONS OF 3-ACYLPYRROLIDINE-2,4-DIONES BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY

Chemischer Informationsdienst ◽

10.1002/chin.198027059 ◽

1980 ◽

Vol 11 (27) ◽

Author(s):

M. J. NOLTE ◽

P. S. STEYN ◽

P. L. WESSELS

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Magnetic Resonance Spectroscopy ◽

Nuclear Magnetic Resonance Spectroscopy ◽

Resonance Spectroscopy ◽

Structural Investigations ◽

X Ray ◽

X Ray Crystallography ◽

Nuclear Magnetic

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ChemInform Abstract: A STUDY ON THE STRUCTURES OF 3-METHOXYCARBONYLRIFAMYCINS BY X-RAY CRYSTALLOGRAPHY AND PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Chemischer Informationsdienst ◽

10.1002/chin.198312070 ◽

1983 ◽

Vol 14 (12) ◽

Author(s):

L. CELLAI ◽

S. CERRINI ◽

A. SEGRE ◽

M. BRUFANI ◽

W. FEDELI ◽

...

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Magnetic Resonance Spectroscopy ◽

Nuclear Magnetic Resonance Spectroscopy ◽

Proton Nuclear Magnetic Resonance ◽

Resonance Spectroscopy ◽

X Ray ◽

X Ray Crystallography ◽

Nuclear Magnetic

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