The Efficacy of Low‐Level Laser Therapy for Shoulder Tendinopathy: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

2014 ◽  
Vol 20 (2) ◽  
pp. 108-125 ◽  
Author(s):  
Sturla Haslerud ◽  
Liv Heide Magnussen ◽  
Jon Joensen ◽  
Rodrigo Alvaro Brandao Lopes‐Martins ◽  
Jan Magnus Bjordal
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Laser Therapy ◽  
Meta Analysis ◽  
Low Level Laser Therapy ◽  
Controlled Trials ◽  
Low Level ◽  
Randomized Controlled ◽  
Low Level Laser ◽  
Level Laser

scholarly journals Ibuprofen and Low-level Laser Therapy for Pain Control during Fixed Orthodontic Therapy: A Systematic Review of Randomized Controlled Trials and Meta-analysis

2017 ◽  
Vol 18 (6) ◽  
pp. 527-533 ◽  
Author(s):  
Faezeh Eslamipour ◽  
Saeed R Motamedian ◽  
Fahimeh Bagheri
Keyword(s):  
Laser Therapy ◽  
Pain Control ◽  
Meta Analysis ◽  
Low Level Laser Therapy ◽  
Controlled Trials ◽  
Low Level ◽  
Orthodontic Therapy ◽  
Randomized Controlled ◽  
Low Level Laser ◽  
Level Laser

ABSTRACT Introduction To systematically review high-quality randomized controlled trials (RCTs) and meta-analysis on the effectiveness of use of ibuprofen and low-level laser therapy (LLLT) for pain control during fixed orthodontic appliance therapy. Materials and methods A web-based systematic search of PubMed and Medline database using relevant keywords was performed in August 2016 limited to the English language studies. Based on inclusion and exclusion criteria, RCTs utilizing blind approach were selected. The quality of studies was analyzed and only high-quality studies were included. Following data extraction, meta-analysis was performed by standardized mean difference Hedges’ (adjusted) g with 95% confidence interval. Results A total number of six studies (four ibuprofen and two LLLT) comprising 315 patients were included. Heterogeneity among ibuprofen studies was small, while large heterogeneity was found among LLLT studies. The results showed that both ibuprofen and LLLT could reduce pain intensity during fixed orthodontic therapy and during 17 days follow-up period. However, this reduction was statistically significant only at 6 to 24 hours postoperatively for ibuprofen and 2 hours and 3 to 7 days for LLLT (p < 0.05). Conclusion Considering the limitations of the current metaanalysis, ibuprofen could alleviate orthodontic archwire activation pain during the 1st day with relatively high level of evidence. Low-level laser therapy could reduce this pain in the long term with limited evidence. Further well-designed RCTs are required to provide more evidence. How to cite this article Eslamipour F, Motamedian SR, Bagheri F. Ibuprofen and Low-level Laser Therapy for Pain Control during Fixed Orthodontic Therapy: A Systematic Review of Randomized Controlled Trials and Meta-analysis. J Contemp Dent Pract 2017;18(6):527-533.

scholarly journals Efficacy of low-level laser therapy on pain and disability in knee osteoarthritis: systematic review and meta-analysis of randomised placebo-controlled trials

BMJ Open ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. e031142 ◽  
Author(s):  
Martin Bjørn Stausholm ◽  
Ingvill Fjell Naterstad ◽  
Jon Joensen ◽  
Rodrigo Álvaro Brandão Lopes-Martins ◽  
Humaira Sæbø ◽  
...  
Keyword(s):  
Systematic Review ◽  
Knee Osteoarthritis ◽  
Laser Therapy ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Low Level Laser Therapy ◽  
Controlled Trials ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

ObjectivesLow-level laser therapy (LLLT) is not recommended in major knee osteoarthritis (KOA) treatment guidelines. We investigated whether a LLLT dose–response relationship exists in KOA.DesignSystematic review and meta-analysis.Data sourcesEligible articles were identified through PubMed, Embase, Cumulative Index to Nursing and Allied Health Literature, Physiotherapy Evidence Database and Cochrane Central Register of Controlled Trials on 18 February 2019, reference lists, a book, citations and experts in the field.Eligibility criteria for selecting studiesWe solely included randomised placebo-controlled trials involving participants with KOA according to the American College of Rheumatology and/or Kellgren/Lawrence criteria, in which LLLT was applied to participants’ knee(s). There were no language restrictions.Data extraction and synthesisThe included trials were synthesised with random effects meta-analyses and subgrouped by dose using the World Association for Laser Therapy treatment recommendations. Cochrane’s risk-of-bias tool was used.Results22 trials (n=1063) were meta-analysed. Risk of bias was insignificant. Overall, pain was significantly reduced by LLLT compared with placebo at the end of therapy (14.23 mm Visual Analogue Scale (VAS; 95% CI 7.31 to 21.14)) and during follow-ups 1–12 weeks later (15.92 mm VAS (95% CI 6.47 to 25.37)). The subgroup analysis revealed that pain was significantly reduced by the recommended LLLT doses compared with placebo at the end of therapy (18.71 mm (95% CI 9.42 to 27.99)) and during follow-ups 2–12 weeks after the end of therapy (23.23 mm VAS (95% CI 10.60 to 35.86)). The pain reduction from the recommended LLLT doses peaked during follow-ups 2–4 weeks after the end of therapy (31.87 mm VAS significantly beyond placebo (95% CI 18.18 to 45.56)). Disability was also statistically significantly reduced by LLLT. No adverse events were reported.ConclusionLLLT reduces pain and disability in KOA at 4–8 J with 785–860 nm wavelength and at 1–3 J with 904 nm wavelength per treatment spot.PROSPERO registration numberCRD42016035587.

Effects of Low-Level Laser Therapy on Muscular Performance and Soreness Recovery in Athletes: A Meta-analysis of Randomized Controlled Trials

2021 ◽  
pp. 194173812110397
Author(s):  
Wun-Ting Luo ◽  
Chieh-Jui Lee ◽  
Ka-Wai Tam ◽  
Tsai-Wei Huang
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Laser Therapy ◽  
Meta Analysis ◽  
Low Level Laser Therapy ◽  
Controlled Trials ◽  
Physically Active ◽  
Muscular Performance ◽  
Randomized Controlled ◽  
Level Laser

Context: Athletes must maintain their peak state of strength. Previous studies have investigated the effect of low-level laser therapy (LLLT) on muscular performance. A previous systematic review and meta-analysis has investigated this issue in healthy participants but not in physically active athletes. Objective: To investigate whether LLLT can improve muscular performance and soreness recovery in athletes. Data Sources: PubMed, EMBASE, and Cochrane Library. Study Selection: Published randomized controlled trials and crossover studies till December 2020. Study Design: Systematic review and meta-analysis. Level of Evidence: Level 3. Data Extraction: Assessment of study quality was rated using the risk of bias assessment method for randomized trials (Cochrane Handbook for Systematic Reviews of Interventions). Results: A total of 24 studies were included. LLLT application before exercise significantly improved lower-limb muscle strength in 24-hour, 48-hour, 96-hour, and 8-week follow-up groups. Furthermore, decreased soreness index, serum creatine kinase concentrations, interleukin-6, and thiobarbituric acid reactive substance concentrations and a trend toward the improvement of contract repetition number and VO2 kinetic outcomes were observed. Conclusion: Although a definite therapeutic effect of LLLT is yet to be established, the current evidence supports that LLLT use improves muscular performance in physically active athletes. Additional trials with large sample sizes and robust design should be conducted before strong recommendations are made.

Effect of low-level laser therapy on pain and disability in patients with plantar fasciitis: A systematic review and meta-analysis

2021 ◽  
pp. 102478
Author(s):  
Janice S. Guimarães ◽  
Fabio L. Arcanjo ◽  
Gustavo Leporace ◽  
Leonardo F. Metsavaht ◽  
Cristiano Sena ◽  
...  
Keyword(s):  
Systematic Review ◽  
Laser Therapy ◽  
Plantar Fasciitis ◽  
Meta Analysis ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser
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