Effects of early Vitamin D supplementation on the prevention of bronchopulmonary dysplasia in preterm infants

2022 ◽  
Author(s):  
Haiyan Ge ◽  
Yanxia Qiao ◽  
Jun Ge ◽  
Junran Li ◽  
Kena Hu ◽  
...  
Keyword(s):  
Vitamin D ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Vitamin D Supplementation

Vitamin D supplementation in the prevention of neonatal bronchopulmonary dysplasia: Is it beneficial?

2022 ◽  
Vol 11 (1) ◽  
pp. 1
Author(s):  
MohamedShawky Elfarargy ◽  
Ghada Al-Ashmawy ◽  
HanyAbd El Fatah El Hady
Keyword(s):  
Vitamin D ◽  
Bronchopulmonary Dysplasia ◽  
Vitamin D Supplementation

scholarly journals Vitamin D Supplementation and T Cell Regulation in Preterm Infants

2019 ◽  
Vol 69 (5) ◽  
pp. 607-610 ◽  
Author(s):  
Hany Aly ◽  
Lamiaa Mohsen ◽  
Indrani Bhattacharjee ◽  
Amr Malash ◽  
Amr Atyia ◽  
...  
Keyword(s):  
Vitamin D ◽  
T Cell ◽  
Preterm Infants ◽  
Vitamin D Supplementation ◽  
Cell Regulation ◽  
T Cell Regulation

scholarly journals Vitamin D and bronchopulmonary dysplasia in preterm infants

2016 ◽  
Vol 36 (10) ◽  
pp. 878-882 ◽  
Author(s):  
K E Joung ◽  
H H Burris ◽  
L J Van Marter ◽  
T F McElrath ◽  
Z Michael ◽  
...  
Keyword(s):  
Vitamin D ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia

Trial of Daily Vitamin D Supplementation in Preterm Infants

PEDIATRICS ◽  
2014 ◽  
Vol 133 (3) ◽  
pp. e628-e634 ◽  
Author(s):  
C. K. Natarajan ◽  
M. J. Sankar ◽  
R. Agarwal ◽  
O. T. Pratap ◽  
V. Jain ◽  
...  
Keyword(s):  
Vitamin D ◽  
Preterm Infants ◽  
Vitamin D Supplementation ◽  
Daily Vitamin

scholarly journals Monitored Supplementation of Vitamin D in Preterm Infants: A Randomized Controlled Trial

2021 ◽  
Author(s):  
Alicja Kołodziejczyk-Nowotarska ◽  
Renata Bokiniec ◽  
Joanna Seliga-Siwecka
Keyword(s):  
Vitamin D ◽  
Preterm Infants ◽  
Controlled Trial ◽  
Vitamin D Supplementation ◽  
Control Group ◽  
Randomized Controlled ◽  
Vitamin D Levels ◽  
Ultrasound Findings ◽  
To Receive ◽  
Vitamin D Toxicity

Appropriate supplementation of vitamin D can affect infections, allergy, and mental and behavioral development. This study aimed to assess the effectiveness of monitored vitamin D supplementation in a population of preterm infants. 109 preterm infants (24 0/7–32 6/7 weeks of gestation) were randomized to receive 500 IU vitamin D standard therapy (n=55; approximately 800-1000 IU from combined sources) or monitored therapy (n=54; with an option of dose modification). 25(OH)D concentrations were measured at birth, 4 weeks of age, and 35, 40, and 52±2 weeks of post-conceptional age (PCA). Vitamin D supplementation was discontinued in 23% of infants subjected to standard treatment due to increased potentially toxic 25(OH)D concentrations (>90 ng/mL) at 40 weeks of PCA. A significantly higher infants’ percentage in the monitored group had safe vitamin D levels (20–80 ng/mL) at 52 weeks of PCA (p=0.017). We observed increased vitamin D levels and abnormal ultrasound findings in five infants. Biochemical markers of vitamin D toxicity were observed in two patients at 52 weeks of PCA in the control group. Inadequate and excessive amounts of vitamin D can lead to serious health problems. Supplementation with 800–1000 IU of vitamin D prevents deficiency and should be monitored to avoid overdose.

scholarly journals PS-206 Maternal/neonatal Vitamin D Deficiency May Be A Risk Factor For Development Of Bronchopulmonary Dysplasia In Preterm Infants

2014 ◽  
Vol 99 (Suppl 2) ◽  
pp. A187.1-A187
Author(s):  
M Cetinkaya ◽  
A Demirhan ◽  
G Buyukkale ◽  
F Cekmez ◽  
T Erener-Ercan ◽  
...  
Keyword(s):  
Vitamin D ◽  
Risk Factor ◽  
Vitamin D Deficiency ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia

Reassessing vitamin D supplementation in preterm infants: a prospective study and review of the literature

2020 ◽  
Vol 33 (10) ◽  
pp. 1273-1281
Author(s):  
Amnon Zung ◽  
Chani Topf-Olivestone ◽  
Eric S. Shinwell ◽  
Lilach Hofi ◽  
Ada Juster-Reicher ◽  
...  
Keyword(s):  
Vitamin D ◽  
Alkaline Phosphatase ◽  
Preterm Infants ◽  
Daily Intake ◽  
Serum Levels ◽  
Vitamin D Supplementation ◽  
Review Of The Literature ◽  
Significant Elevation ◽  
Total Daily Intake ◽  
A Prospective Study

AbstractObjectivesRecommendations for vitamin D (VitD) intake and target serum levels of 25(OH)D in preterm infants are diverse. We hypothesized that preterm infants with low birth weight (BW) have low dietary intake of VitD and therefore should be supplemented with higher amounts of VitD.MethodsInfants with BW < 2 kg were supplemented with 600 units of VitD a day during the first 2–6 weeks of life, whereas infants with BW>2 kg continued with the routine supplementation of 400 units of VitD daily. Serum levels of 25(OH)D, calcium, phosphorous, alkaline phosphatase (AP) and parathyroid hormone (PTH) were assessed 24 h after birth and before discharge. The total daily intake of vitD was calculated in each infant.ResultsSixty-two infants were enrolled, 49 with BW < 2 kg. After birth, only 24% had sufficient levels of 25(OH)D, whereas before discharge 45 of 54 infants (83%) available for analysis reached sufficient levels of 25(OH)D. All 54 infants demonstrated significant elevation in serum levels of calcium, phosphorous, AP and significant reduction in PTH levels. The total daily intake of VitD was lower than recommended (800–1000 IU/d) in 16 of 45 infants with BW < 2 kg (36%) and in all nine infants with BW>2 kg. Nevertheless, only 2 of 25 infants with insufficient intake of VitD demonstrated insufficient levels of serum 25(OH)D. No case of vitamin D excess was recorded.ConclusionsIncreased supplementation of VitD (600 IU/d) for premature newborns with BW < 2 kg is effective in increasing both total daily intake of VitD and serum levels of 25(OH)D.

The association of vitamin D and vitamin E levels at birth with bronchopulmonary dysplasia in preterm infants

2021 ◽  
Author(s):  
Haiyan Ge ◽  
Weina Liu ◽  
Huimin Li ◽  
Ming Zhang ◽  
Mengbin Zhang ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin E ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia
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