Can bronchial challenge test with adenosine or methacholine at preschool age predict school‐age asthma?

2021 ◽  
Vol 56 (10) ◽  
pp. 3200-3208
Author(s):  
Tal Golan‐Lagziel ◽  
Avigdor Mandelberg ◽  
Yonatan Wolfson ◽  
Dorit Ater ◽  
Keren Armoni Domany
Keyword(s):  
Challenge Test ◽  
Preschool Age ◽  
School Age ◽  
Bronchial Challenge

scholarly journals Anger in infancy and its implications: History of attachment in mother–child and father–child relationships as a moderator of risk

2018 ◽  
Vol 31 (04) ◽  
pp. 1353-1366 ◽  
Author(s):  
Rebecca L. Brock ◽  
Grazyna Kochanska
Keyword(s):  
Preschool Age ◽  
Complex Nature ◽  
School Age ◽  
Strange Situation ◽  
Car Seat ◽  
Early School ◽  
History Of ◽  
Early School Age ◽  
The Impact ◽  
Parent Child

AbstractGrowing research has documented distinct developmental sequelae in insecure and secure parent–child relationships, supporting a model of early attachment as moderating future developmental processes rather than, or in addition to, a source of direct effects. We explored maladaptive developmental implications of infants’ anger proneness in 102 community families. Anger was assessed in infancy through observations in the Car Seat episode and parents’ ratings. Children's security with parents was assessed in the Strange Situation paradigm at 15 months. At preschool age, child negativity (defiance and negative affect) was observed in interactions with the parent, and at early school age, oppositionality was rated by parents and teachers. Security was unrelated to infant anger; however, it moderated associations between infant anger and future maladaptive outcomes, such that highly angry infants embarked on a negative trajectory in insecure, but not in secure, parent–child dyads. For insecure, but not secure, mother–child dyads, infants’ mother-rated anger predicted negativity at preschool age. For insecure, but not secure, father–child dyads, infants’ anger in the Car Seat predicted father- and teacher-rated oppositional behavior at early school age. Results highlight the developmentally complex nature of the impact of attachment, depending on the relationship with mother versus father, type of measure, and timing of effects.

scholarly journals ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing

2018 ◽  
Vol 52 (5) ◽  
pp. 1801033 ◽  
Author(s):  
Teal S. Hallstrand ◽  
Joerg D. Leuppi ◽  
Guy Joos ◽  
Graham L. Hall ◽  
Kai-Håkon Carlsen ◽  
...  
Keyword(s):  
Airway Hyperresponsiveness ◽  
Task Force ◽  
Challenge Test ◽  
Technical Standard ◽  
Bronchial Challenge ◽  
Airway Narrowing ◽  
Airway Function ◽  
Challenge Testing ◽  
Challenge Tests ◽  
Indirect Tests

Recently, this international task force reported the general considerations for bronchial challenge testing and the performance of the methacholine challenge test, a “direct” airway challenge test. Here, the task force provides an updated description of the pathophysiology and the methods to conduct indirect challenge tests. Because indirect challenge tests trigger airway narrowing through the activation of endogenous pathways that are involved in asthma, indirect challenge tests tend to be specific for asthma and reveal much about the biology of asthma, but may be less sensitive than direct tests for the detection of airway hyperresponsiveness. We provide recommendations for the conduct and interpretation of hyperpnoea challenge tests such as dry air exercise challenge and eucapnic voluntary hyperpnoea that provide a single strong stimulus for airway narrowing. This technical standard expands the recommendations to additional indirect tests such as hypertonic saline, mannitol and adenosine challenge that are incremental tests, but still retain characteristics of other indirect challenges. Assessment of airway hyperresponsiveness, with direct and indirect tests, are valuable tools to understand and to monitor airway function and to characterise the underlying asthma phenotype to guide therapy. The tests should be interpreted within the context of the clinical features of asthma.

scholarly journals Spirometry and mannitol bronchial challenge test among firefighters in Bhuj district: a questionnaire based study

2017 ◽  
Vol 4 (5) ◽  
pp. 1434
Author(s):  
Kashyap Buch ◽  
Vinayak Chauhan
Keyword(s):  
Nitric Oxide ◽  
Lung Disease ◽  
Chronic Lung Disease ◽  
Respiratory Symptoms ◽  
Challenge Test ◽  
Shortness Of Breath ◽  
Chest Tightness ◽  
Bronchial Challenge ◽  
Challenge Tests ◽  
Skin Prick Tests

Background: Asthma is a common chronic lung disease that inflames and narrows the airways. It causes recurring period of wheezing, chest tightness, shortness of breath and coughing.Methods: A questionnaire, spirometry, direct and indirect airway challenge tests, exhaled nitric oxide, and skin-prick tests were administered prospectively to 100 out of 120 firefighters employed in Bhuj district, Gujarat, India. Asthma was defined as the combination of respiratory symptoms with airway hyper responsiveness.Results: Twenty out of 100 firefighters (12%) had physician-diagnosed asthma, which could be confirmed in 8 firefighters. In contrast, asthma was diagnosed in 28% (28 of 100 firefighters). Wheezing was the most sensitive symptom for the diagnosis of asthma (sensitivity, 88%; specificity, 90%).Conclusions: Asthma was considerably under diagnosed in firefighters. The combination of a structured symptom questionnaire with a bronchial challenge test allows identifying patients with asthma and should routinely be used in the assessment of active firefighters and may be of help when evaluating candidates for this profession.

scholarly journals RESEARCH OF INFLUENCE RISK FACTORS ON ERUPTION SECOND TEETH OF CHILDREN IN VLADIVOSTOK

2020 ◽  
Vol 15 (4) ◽  
pp. 170-176
Author(s):  
Anna Yatsenko ◽  
Lidiya Trankovskaya ◽  
Yury Pervov ◽  
Olga Gritsina ◽  
Elena Anischenko
Keyword(s):  
Risk Factors ◽  
Preschool Age ◽  
Permanent Teeth ◽  
School Age ◽  
Way Of Life ◽  
Food Ingredients ◽  
Pregnancy And Childbirth ◽  
Habitat Factors ◽  
Potential Risk Factors ◽  
Continuous Work

Subject. The research of influence risk factors is conducted on secondary dentition of the children's population of the region. The share contribution is established habitat factors in an indicator of a tooth maturity of children. Purpose — studying influences of risk factors on secondary dentition of children in Vladivostok. Methodology. Dental maturity was assessed by the eruption time of permanent teeth and their number. Factors of pregnancy and childbirth, early childhood, medical and biological factors, social and hygienic factors characterizing living conditions, as well as hygienic-regulated factors of lifestyle by means of questionnaires of parents (guardians) of children have been studied. The hygienic assessment of the actual food was carried out by means of determination of average amount of the studied food ingredients of diets of children preschool age according to the menu apportions and specially developed questionnaires, children younger school age – by questioning of parents (trustees) of children. Results. It was revealed that the central incisors were the first in children of both sexes on the lower jaw, and the first molars on the upper jaw. Girls had earlier eruption through permanent teeth. Potential risk factors of disturbance of eruption are established second teeth of children of preschool and younger school age. Are revealed imbalance of food of children, non-performance of the recommended volume physical activity and duration of walks, discrepancy of duration day dream to hygienic recommendations and continuous work on the computer, tablet, notebook. Dependences between studied potential are defined risk factors and tooth maturity of children. Identification causal is carried out investigative bonds in the system of factors of the habitat and eruption of constants teeth of children. It is established that the maximum influence on an indicator of a tooth maturity render: nutrient structure of food allowances of the child, food of women in time pregnancies, the hygienic normalized factors of a way of life of children. Conclusions. Share contribution of each of factors to forming of a tooth maturity of a children's organism allowed to prove and develop a complex of actions for prevention scientifically disturbances of health among the children's population of the region.

scholarly journals Сase-technologies in practice-oriented training of future teachers of preschool and primary general education

2021 ◽  
Vol 113 ◽  
pp. 00036
Author(s):  
N.A. Gushchina ◽  
V.N. Zinovieva ◽  
I.V. Mikityuk
Keyword(s):  
Higher Education ◽  
General Education ◽  
Primary Schools ◽  
Cognitive Activity ◽  
Preschool Age ◽  
School Age ◽  
Pedagogical Practice ◽  
Future Teachers ◽  
Case Technologies ◽  
Primary School Age

The article deals with the problem of convergence of fundamental pedagogical education in higher education and real pedagogical practice in preschool organizations and primary schools for the formation of children’s cognitive activity. The article presents the experience of testing pedagogical conditions for the use of case technologies in preparing future teachers for the process of forming prerequisites for cognitive activity in preschool age and cognitive universal educational actions in primary school age.

scholarly journals Italian adaptation of the Multilingual Assessment Instrument for Narratives

2020 ◽  
Vol 64 ◽  
pp. 139-146
Author(s):  
Chiara Levorato ◽  
Maja Roch
Keyword(s):  
Language Development ◽  
Assessment Tool ◽  
Preschool Age ◽  
Assessment Instrument ◽  
Language Delay ◽  
School Age ◽  
Research Projects ◽  
Narrative Competence ◽  
Italian Version ◽  
Italian Context

This paper presents the Italian version of the Multilingual Assessment tool for Narratives (MAIN), describes how it was developed and reports on some recent uses of MAIN within the Italian context. The Italian MAIN has been used in different research projects and for clinical purposes; results have been presented at conferences and in peer reviewed papers. The results indicate that MAIN is an appropriate assessment tool for evaluating children’s narrative competence, in production and comprehension from preschool age (5 years) to school age (8 years) in typical language development, bilingual development and language delay/disorders.

scholarly journals Comparison of basic regional cerebral oxygen saturation values in patients of different ages: a pilot study

2020 ◽  
Vol 48 (8) ◽  
pp. 030006052093686
Author(s):  
Chaohui Lian ◽  
Peng Li ◽  
Ning Wang ◽  
Yi Lu ◽  
Wangning Shangguan
Keyword(s):  
Oxygen Saturation ◽  
Elective Surgery ◽  
Age Groups ◽  
The Elderly ◽  
Preschool Age ◽  
Cerebral Oxygen Saturation ◽  
Cerebral Oxygen ◽  
School Age ◽  
Regional Cerebral Oxygen Saturation ◽  
Significant Difference

Objective To explore the basic values of regional cerebral oxygen saturation (rSO2) among different age groups. Methods One hundred twenty patients who were scheduled for elective surgery aged 0 to 80 years (American Society of Anesthesiologists [ASA] physical status I or II) or neonates just after birth via cesarean section were enrolled and divided into the following six groups: infant (0 month and ≤12 months), toddler (>1 and ≤3 years old), preschool (>3 and ≤6 years old), school age (>6 and ≤18 years old), adult (>18 and ≤65 years old), and elderly (>65 and ≤80 years old) groups. There were 20 patients in each group. Results The basic values of rSO2 in infant, toddler, preschool, school age, adults, and elderly groups were 70.41% ± 4.66%, 72.43% ± 3.81%, 70.77% ± 3.27%, 70.62% ± 2.20%, 69.76% ± 6.02%, and 62.69% ± 3.14%, respectively. The basic value in the elderly group was lower compared with other five groups. There was no significant difference among infant, toddler, preschool age, school age, and adult groups. Conclusions The basic value of rSO2 in elderly patients is lower. Age is an important factor that affects the underlying value of rSO2.

What do children know about German verb prefixes?

2019 ◽  
Vol 14 (2) ◽  
pp. 274-297
Author(s):  
Veronika Mattes
Keyword(s):  
Experimental Study ◽  
Preschool Age ◽  
School Age ◽  
Semantic Transparency ◽  
Lexical Knowledge ◽  
Verbal Prefixes ◽  
Early School ◽  
Speech Data ◽  
Early School Age ◽  
Semantic Awareness

Abstract Not much is known about how children cope with the task of acquiring the complex, polyfunctional, and often abstract and idiosyncratic system of German verbal prefixes. This paper presents an experimental study on children’s knowledge, i.e. their morphological and semantic awareness, of the five verbal prefixes be‑, ent‑, er‑, ver‑, and zer‑ in preschool age and early school age. The experiment combines a decision and a definition task involving canonical and novel prefix verbs, and it examines the influence of context on the recognition of the verbs. The results of the study show that, in general, the knowledge of prefix verbs increases significantly between 6 and 8 years. Preschoolers have preliminary, but still very labile representations of the five verbal prefixes, school children have established much more independent representations, however, the lexical knowledge they have about prefixes and prefixed verbs is still fragmentary. The five prefixes under investigation differ considerably with respect to their morpho-semantic transparency. Higher transparency results in good passive knowledge of the prefixes, even when they are rarely used by the children spontaneously, such as the infrequent, but semantically salient prefix ent- (ent-kommen ‘escape’), that is much better known to children than spontaneous speech data would suggest.

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