Opportunities and challenges of pharmacotherapy for pulmonary arterial hypertension in children

2020 ◽  
Author(s):  
Charissa W. Kam ◽  
Fadel E. Ruiz
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Pulmonary Arterial ◽  
Hypertension In Children

scholarly journals Effectiveness and Safety of Inhaled Treprostinil for the Treatment of Pulmonary Arterial Hypertension in Children

2012 ◽  
Vol 110 (11) ◽  
pp. 1704-1709 ◽  
Author(s):  
Usha Krishnan ◽  
Shinichi Takatsuki ◽  
Dunbar D. Ivy ◽  
Jason Kerstein ◽  
Michelle Calderbank ◽  
...  
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Pulmonary Arterial ◽  
Hypertension In Children

Clinical impact of subcutaneous treprostinil in trisomy 21 patient with pulmonary arterial hypertension associated with CHD

2022 ◽  
pp. 1-3
Author(s):  
Ryusuke Numata ◽  
Kiyohiro Takigiku ◽  
Kouta Takei
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Pulmonary Artery ◽  
Arterial Hypertension ◽  
Exercise Capacity ◽  
Trisomy 21 ◽  
Pulmonary Artery Hypertension ◽  
Idiopathic Pulmonary Arterial Hypertension ◽  
Clinical Impact ◽  
Pulmonary Arterial ◽  
Hypertension In Children

Abstract Subcutaneous treprostinil is commonly used to improve idiopathic pulmonary arterial hypertension in children. However, its effectiveness has not been reported in trisomy 21. We report the case of 9-year-old boy in trisomy 21 with CHD-pulmonary artery hypertension after surgical correction of CHD. Haemodynamics and exercise capacity dramatically improved with a transition from oral selexipag to subcutaneous treprostinil.

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