Global and regional lung function in cystic fibrosis measured by electrical impedance tomography

2016 ◽  
Vol 51 (11) ◽  
pp. 1191-1199 ◽  
Author(s):  
Sylvia Lehmann ◽  
Steffen Leonhardt ◽  
Chuong Ngo ◽  
Lukas Bergmann ◽  
Ines Ayed ◽  
...  
2016 ◽  
Vol 2 (1) ◽  
pp. 633-636 ◽  
Author(s):  
Sabine Krueger-Ziolek ◽  
Benjamin Schullcke ◽  
Zhanqi Zhao ◽  
Bo Gong ◽  
Knut Moeller

AbstractElectrical impedance tomography (EIT) can be used to monitor regional lung ventilation. Due to its relatively high temporal resolution, EIT has already been applied during lung function tests in spontaneously breathing subjects with obstructive lung diseases like chronic obstructive pulmonary disease (COPD) or cystic fibrosis (CF). In our study, ratios of the maximal volume exhaled in 1 s during forced expiration and forced vital capacity (FEV1/FVC) were calculated in predefined lung regions for five CF patients and five lung healthy subjects. The degree of FEV1/FVC homogeneity was assessed by using a slightly modified version of the global inhomogeneity index (GIFEV1/FVC). CF patients showed a higher degree of inhomogeneity in pixel FEV1/FVC than lung healthy subjects. Since EIT is able to deliver regional information to assess airway obstruction in CF patients, it might represent a promising supplement to existing methods like spirometry providing global lung parameters.


2017 ◽  
Vol 53 (3) ◽  
pp. 293-301 ◽  
Author(s):  
Barbara Vogt ◽  
Sarah Löhr ◽  
Zhanqi Zhao ◽  
Christian Falkenberg ◽  
Tobias Ankermann ◽  
...  

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