scholarly journals Efficacy and long-term outcomes of palivizumab prophylaxis to prevent respiratory syncytial virus infection in infants with cystic fibrosis in Northern Ireland

2016 ◽  
Vol 51 (4) ◽  
pp. 379-385 ◽  
Author(s):  
H.E. Groves ◽  
L. Jenkins ◽  
M. Macfarlane ◽  
A. Reid ◽  
F. Lynn ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Respiratory Syncytial Virus ◽  
Northern Ireland ◽  
Virus Infection ◽  
Respiratory Syncytial Virus Infection ◽  
Long Term Outcomes ◽  
Syncytial Virus

scholarly journals Respiratory Syncytial Virus Infection Disrupts Monolayer Integrity and Function in Cystic Fibrosis Airway Cells

Viruses ◽  
2013 ◽  
Vol 5 (9) ◽  
pp. 2260-2271 ◽  
Author(s):  
Michele Kong ◽  
Patrick Maeng ◽  
Jeong Hong ◽  
Rhonda Szczesniak ◽  
Eric Sorscher ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Respiratory Syncytial Virus ◽  
Virus Infection ◽  
Respiratory Syncytial Virus Infection ◽  
Cystic Fibrosis Airway ◽  
Syncytial Virus ◽  
And Function ◽  
Airway Cells

scholarly journals Severe respiratory disease caused by human respiratory syncytial virus impairs language learning during early infancy

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Marcela Peña ◽  
Cristina Jara ◽  
Juan C. Flores ◽  
Rodrigo Hoyos-Bachiloglu ◽  
Carolina Iturriaga ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Virus Infection ◽  
Language Learning ◽  
Respiratory Infection ◽  
Respiratory Syncytial Virus Infection ◽  
Learning Difficulties ◽  
Human Respiratory Syncytial Virus ◽  
Severe Respiratory Infection ◽  
Syncytial Virus

AbstractHuman respiratory syncytial virus infection is a leading cause of pediatric morbidity and mortality. A previous murine study showed that during severe acute respiratory infections the virus invades the central nervous system, and that infected animals evolve with long-lasting learning difficulties associated with long-term potentiation impairment in their hippocampus. We hypothesized here that human infants who presented a severe episode of respiratory syncytial virus infection before 6 months of age would develop long-term learning difficulties. We measured the acquisition of the native phoneme repertoire during the first year, a milestone in early human development, comprising a reduction in the sensitivity to the irrelevant nonnative phonetic information and an increase in the sensitivity to the information relevant for the native one. We found that infants with a history of severe respiratory infection by the human respiratory syncytial virus presented poor distinction of native and nonnative phonetic contrasts at 6 months of age, and remained atypically sensitive to nonnative contrasts at 12 months, which associated with weak communicative abilities. Our results uncover previously unknown long-term language learning difficulties associated with a single episode of severe respiratory infection by the human respiratory syncytial virus, which could relate to memory impairments.

Respiratory syncytial virus infection in a murine model of cystic fibrosis

2006 ◽  
Vol 78 (5) ◽  
pp. 651-658 ◽  
Author(s):  
Giuseppe N. Colasurdo ◽  
Jason J. Fullmer ◽  
Okan Elidemir ◽  
Constance Atkins ◽  
Amir M. Khan ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Respiratory Syncytial Virus ◽  
Virus Infection ◽  
Respiratory Syncytial Virus Infection ◽  
Murine Model ◽  
Syncytial Virus
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