Geographic variations in cystic fibrosis: An analysis of the U.S. CF Foundation Registry

2015 ◽  
Vol 50 (8) ◽  
pp. 754-762 ◽  
Author(s):  
Benjamin T. Kopp ◽  
Lisa Nicholson ◽  
Grace Paul ◽  
Joseph Tobias ◽  
Chandar Ramanathan ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Geographic Variations ◽  
The U.S

The U.S. Food and Drug Administration's Experience with Ivacaftor in Cystic Fibrosis. Establishing Efficacy Using In Vitro Data in Lieu of a Clinical Trial

2018 ◽  
Vol 15 (1) ◽  
pp. 1-2 ◽  
Author(s):  
Anthony G. Durmowicz ◽  
Robert Lim ◽  
Hobart Rogers ◽  
Curtis J. Rosebraugh ◽  
Badrul A. Chowdhury
Keyword(s):  
Clinical Trial ◽  
Cystic Fibrosis ◽  
Vitro Data ◽  
In Vitro Data ◽  
The U.S

scholarly journals Inpatient Health Care Trends Among Adult Cystic Fibrosis Patients In The U.S

2011 ◽  
Author(s):  
Benjamin T. Kopp ◽  
Wei Wang ◽  
Kelly Kelleher ◽  
Deena Chisolm ◽  
Karen McCoy
Keyword(s):  
Health Care ◽  
Cystic Fibrosis ◽  
The U.S

scholarly journals Mortality Due to Cystic Fibrosis over a 36-Year Period in Spain: Time Trends and Geographic Variations

2019 ◽  
Vol 16 (1) ◽  
pp. 119 ◽  
Author(s):  
Ana Villaverde-Hueso ◽  
Germán Sánchez-Díaz ◽  
Francisco J. Molina-Cabrero ◽  
Elisa Gallego ◽  
Manuel Posada de la Paz ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Time Trends ◽  
Health Planning ◽  
International Classification Of Diseases ◽  
Mortality Rates ◽  
Population Based ◽  
Mediterranean Coast ◽  
Geographic Variations ◽  
Classification Of Diseases ◽  
Underlying Cause Of Death

The aim of this study is to analyze population-based mortality attributed to cystic fibrosis (CF) over 36 years in Spain. CF deaths were obtained from the National Statistics Institute, using codes 277.0 from the International Classification of Diseases (ICD) ninth revision (ICD9-CM) and E84 from the tenth revision (ICD10) to determine the underlying cause of death. We calculated age-specific and age-adjusted mortality rates, and time trends were assessed using joinpoint regression. The geographic analysis by district was performed by standardized mortality ratios (SMRs) and smoothed-SMRs. A total of 1002 deaths due to CF were identified (50.5% women). Age-adjusted mortality rates fell by −0.95% per year between 1981 and 2016. The average age of death from CF increased due to the annual fall in the mortality of under-25s (−3.77% males, −2.37% females) and an increase in over-75s (3.49%). We identified districts with higher than expected death risks in the south (Andalusia), the Mediterranean coast (Murcia, Valencia, Catalonia), the West (Extremadura), and the Canary Islands. In conclusion, in this study we monitored the population-based mortality attributed to CF over a long period and found geographic differences in the risk of dying from this disease. These findings complement the information provided in other studies and registries and will be useful for health planning.

scholarly journals Impact of Socioeconomic Position on Access to the U.S. Lung Transplant Waiting List in a Matched Cystic Fibrosis Cohort

2020 ◽  
Vol 17 (11) ◽  
pp. 1384-1392 ◽  
Author(s):  
Carli J. Lehr ◽  
Aliza K. Fink ◽  
Melissa Skeans ◽  
Albert Faro ◽  
Gabriela Fernandez ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Socioeconomic Position ◽  
Lung Transplant ◽  
Waiting List ◽  
The U.S

scholarly journals Inpatient healthcare trends among adult cystic fibrosis patients in the U.S.

2011 ◽  
Vol 47 (3) ◽  
pp. 245-251 ◽  
Author(s):  
Benjamin T. Kopp ◽  
Wei Wang ◽  
Deena J. Chisolm ◽  
Kelly J. Kelleher ◽  
Karen S. McCoy
Keyword(s):  
Cystic Fibrosis ◽  
Healthcare Trends ◽  
The U.S

scholarly journals The Geography of Chronic Pain in the United States and Canada.

2021 ◽  
Author(s):  
Anna Zajacova ◽  
Jinhyung Lee ◽  
Hanna Grol-Prokopczyk
Keyword(s):  
National Level ◽  
Decomposition Methods ◽  
The United States ◽  
Deep South ◽  
Geographic Variations ◽  
Cross Sectional ◽  
National Geographic ◽  
Pain Frequency ◽  
The Difference ◽  
The U.S

Our understanding of population pain epidemiology is largely based on national-level analyses. This focus, however, neglects potential cross-national, and especially sub-national, geographic variations in pain, even though geographic comparisons could shed new light on factors that drive or protect against pain. This article presents the first comparative analysis of pain in the U.S. and Canada, comparing the countries in aggregate and analyzing variation across states and provinces. Analyses are based on cross-sectional data collected in 2020 from 2,124 U.S. and 2,110 Canadian adults 18 years and older. Our pain measure is a product of pain frequency and pain-related interference with daily activities. We use regression and decomposition methods to link socioeconomic characteristics and pain, and inverse-distance weighting spatial interpolation to map pain scores. We find significantly and substantially higher pain in the U.S. than in Canada. The difference is accounted for by Americans' lower economic wellbeing. Additionally, we find variation in pain within countries; the variation is statistically significant across U.S. states. Further, we identify nine hotspot states in the Deep South, Appalachia, and the West where respondents have significantly higher pain than those in the rest of the U.S. or Canada. This excess pain is partly attributable to economic distress, but a large part remains unexplained; we speculate that it may reflect the sociopolitical context of the hotspot states. Overall, our findings identify areas with high need for pain prevention and management; they also other scholars to consider geographic factors as important contributors to population pain.

scholarly journals Healthcare Cost and Utilization before and after Diagnosis of Pseudomonas aeruginosa among Patients with Non-Cystic Fibrosis Bronchiectasis in the U.S.

2017 ◽  
Vol 5 (4) ◽  
pp. 20 ◽  
Author(s):  
Christopher Blanchette ◽  
Joshua Noone ◽  
Glenda Stone ◽  
Emily Zacherle ◽  
Ripsi Patel ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Pseudomonas Aeruginosa ◽  
Healthcare Cost ◽  
Before And After ◽  
The U.S
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