Inhaled nitric oxide combined with prostacyclin and adrenomedullin in acute respiratory failure with pulmonary hypertension in piglets

2007 ◽  
Vol 42 (11) ◽  
pp. 1048-1056 ◽  
Author(s):  
Carlo Dani ◽  
Vittorio Pavoni ◽  
Iuri Corsini ◽  
Mariangela Longini ◽  
Gabriele Gori ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Pulmonary Hypertension ◽  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Inhaled Nitric Oxide

Partial liquid ventilation combined with inhaled nitric oxide in acute respiratory failure with pulmonary hypertension in piglets

1996 ◽  
Vol 22 (S1) ◽  
pp. S138-S138
Author(s):  
Gerfried Zobel ◽  
Bernd Urlesberger ◽  
Drago Dacar ◽  
Siegfried Rödl ◽  
Friz Reiterer ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Pulmonary Hypertension ◽  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Inhaled Nitric Oxide ◽  
Partial Liquid Ventilation ◽  
Liquid Ventilation

scholarly journals Efficacy of inhaled nitric oxide in neonates with hypoxic respiratory failure and pulmonary hypertension: the Japanese experience

2018 ◽  
Vol 46 (6) ◽  
pp. 657-663 ◽  
Author(s):  
Satoshi Suzuki ◽  
Hajime Togari ◽  
Jim L. Potenziano ◽  
Michael D. Schreiber
Keyword(s):  
Nitric Oxide ◽  
Pulmonary Hypertension ◽  
Respiratory Failure ◽  
Negative Impact ◽  
Survival Rates ◽  
Oxygenation Index ◽  
Inhaled Nitric Oxide ◽  
Preterm Neonates ◽  
Therapeutic Trial ◽  
Hypoxic Respiratory Failure

AbstractObjective:To analyze data from a registry of Japanese neonates with hypoxic respiratory failure associated with pulmonary hypertension (PH) to compare the effectiveness of inhaled nitric oxide (iNO) in neonates born <34 weeks vs. ≥34 weeks gestational age (GA).Materials and methods:iNO was administered according to approved Japanese product labeling. Study data were collected before iNO administration and at predefined intervals until discontinuation.Results:A total of 1,114 neonates were included (n=431, <34 weeks GA; n=675, ≥34 weeks GA; n=8, missing age data). Mean decrease from baseline oxygenation index (OI) was similar in both age groups. OI reduction was more pronounced in the <34 weeks subgroups with baseline OI ≥25. Survival rates were similar in the <34 weeks GA and ≥34 weeks GA groups stratified by baseline OI (OI<15, 89% vs. 93%; 15≤OI<25, 85% vs. 91%; 25≤OI≤40, 73% vs. 79%; OI>40, 64% vs. 66%).Conclusion:iNO improved oxygenation in preterm neonates as effectively as in late preterm and term neonates, without negative impact on survival. If clinically significant PH is present, as measured by pulse oximetry or echocardiography, a therapeutic trial of iNO might be indicated for preterm neonates.

scholarly journals Cardiorespiratory effects of inhaled nitric oxide during acute hypercapnia with and without correction of blood pH in a acute respiratory failure in piglets

Critical Care ◽  
10.1186/cc417 ◽  
1999 ◽  
Vol 3 (Suppl 1) ◽  
pp. P042
Author(s):  
G Zobel ◽  
S Rödl ◽  
B Urlesberger ◽  
M Bermoser ◽  
W Schwinger ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Inhaled Nitric Oxide ◽  
Blood Ph
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