Ventilation-perfusion abnormalities in the preterm infant with hyaline membrane disease: A two-compartment model of the neonatal lung

1990 ◽  
Vol 9 (4) ◽  
pp. 206-213 ◽  
Author(s):  
Ivan L. Hand ◽  
Eric K. Shepard ◽  
Alfred N. Krauss ◽  
Peter A. M. Auld
Keyword(s):  
Preterm Infant ◽  
Compartment Model ◽  
Hyaline Membrane Disease ◽  
Two Compartment Model ◽  
Hyaline Membrane ◽  
Neonatal Lung

scholarly journals Intraventricular haemorrhage in the preterm infant without hyaline membrane disease.

1977 ◽  
Vol 52 (6) ◽  
pp. 447-451 ◽  
Author(s):  
J S Wigglesworth ◽  
P A Davies ◽  
I H Keith ◽  
S A Slade
Keyword(s):  
Preterm Infant ◽  
Intraventricular Haemorrhage ◽  
Hyaline Membrane Disease ◽  
Hyaline Membrane

Family History of Asthma in Infants with Bronchopulmonary Dysplasia

PEDIATRICS ◽  
1980 ◽  
Vol 65 (6) ◽  
pp. 1140-1144 ◽  
Author(s):  
Bruce G. Nickerson ◽  
Lynn M. Taussig
Keyword(s):  
Bronchopulmonary Dysplasia ◽  
Hyaline Membrane Disease ◽  
Assisted Ventilation ◽  
Respiratory Illnesses ◽  
Clinical Criteria ◽  
Hyaline Membrane ◽  
Neonatal Lung ◽  
History Of ◽  
Second Degree

The role of genetic or familial factors in the development of bronchopulmonary dysplasia (BPD) has not been evaluated. Detailed histories concerning asthma, allergy, and other lung diseases were obtained on first and second degree relatives of 17 infants with BPD, and 21 infants who had hyaline membrane disease but who did not develop BPD (HMD group). All infants in the BPD and HMD groups had hyaline membrane disease requiring assisted ventilation and greater than 50% inspired oxygen in the first five days of life. The diagnosis of HMD and BPD were made on radiographic and clinical criteria. Of the 17 infants with BPD, 13 had first or second degree relatives with physician-diagnosed asthma, compared to seven of 21 in the HMD group (P < .01). In addition, a significantly greater number of relatives of BPD infants (P < .005) had been hospitalized for their asthma as compared to HMD relatives. There were no differences between the groups for allergic rhinitis, eczema, bronchitis, emphysema, chronic cough, smoking, or wheezing with respiratory illnesses. These results suggest the possibility that airways with a genetic predisposition for reactivity may become highly reactive following neonatal lung disorders and their treatment. These irritable airways may then contribute to the development, or progression, or both of BPD.

scholarly journals Relationship Between Incidence of Hyaline Membrane Disease and Maternal Hypertension During Pregnancy

2017 ◽  
Vol 38 (3-4) ◽  
pp. 47
Author(s):  
Lasmida Nazir Nuriman ◽  
Dadang Sjarif Hidajat
Keyword(s):  
Distress Syndrome ◽  
Hyaline Membrane Disease ◽  
Cross Sectional Study ◽  
Type I ◽  
Cross Sectional ◽  
Hypertension In Pregnancy ◽  
Hyaline Membrane ◽  
Neonatal Respiratory Distress ◽  
Maternal Hypertension ◽  
The Relationship

There have been controversies over the eiTect of hypertension in pregnancy on the incidence of type I neonatal respiratory distress syndrome or hyaline membrane disease (HMD). We investigated the relationship between the incidence of HMD and maternal hypertension during pregnancy in 91 infants at 34 weeks gestation or less. This retrospective cross sectional study included all live born babies between May 1, 1994 and April 30, 1995 at Dr. Hasan Sadikin General Hospital, Bandung. Maternal hypertension during pregnancy was diagnosed in 38 mothers of91 infants studied. The incidence of HMD (5%) in the maternal hypertension during pregnancy group was significantly lower than the 62% in the normotensive group (p<0.01). There was a negative correlation between the occurence of HMD and hypertension during pregnancy. We conclude that the risk of developing HMD in infants born to hypertensive mothers is significantly lower than those born to normotensive mothers.

Two-Compartment Model of Cholesterol Kinetics for Establishment of Treatment Strategy of LDL Apheresis in Nephrotic Hypercholesterolemia

1994 ◽  
Vol 12 (6) ◽  
pp. 317-326 ◽  
Author(s):  
Masatomo Yashiro ◽  
Eri Muso ◽  
Munehiro Matsushima ◽  
Ryoichi Nagura ◽  
Kenji Sawanishi ◽  
...  
Keyword(s):  
Treatment Strategy ◽  
Compartment Model ◽  
Ldl Apheresis ◽  
Two Compartment Model

Clearance and Non-Invasive Determination of the Hepatic Extraction of Indocyanine Green in Baboons and Man

1983 ◽  
Vol 64 (2) ◽  
pp. 207-212 ◽  
Author(s):  
S. L. Grainger ◽  
P. W. N. Keeling ◽  
I. M. H. Brown ◽  
J. H. Marigold ◽  
R. P. H. Thompson
Keyword(s):  
Indocyanine Green ◽  
Accurate Determination ◽  
Liver Blood Flow ◽  
Compartment Model ◽  
Hepatic Extraction ◽  
Non Invasive ◽  
Two Compartment Model ◽  
Hepatic Extraction Ratio ◽  
Plasma Disappearance Curve

1. The disposition of an intravenous bolus of indocyanine green (ICG) has been studied in healthy man and baboons using a novel analysis of a two compartment pharmacokinetic model. 2. This analysis enabled the hepatic extraction ratio (ER) of dye to be determined solely from the plasma disappearance curve, and the ER determined did not differ from that measured by hepatic vein catheterization. 3. When compared with clearance measured at steady state, the two compartment model gave a significantly more accurate determination of plasma clearance than did the conventional one compartment model. 4. It is concluded that, in health, liver blood flow may be calculated accurately and noninvasively after a single intravenous injection of ICG.

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