Lung pathology after high frequency jet ventilation combined with low rate intermittent mandatory ventilation in a canine model of meconium aspiration

1988 ◽  
Vol 4 (3) ◽  
pp. 144-149 ◽  
Author(s):  
Martin Keszler ◽  
R. Scott Klappenbach ◽  
Eileen Reardon
Keyword(s):  
High Frequency ◽  
Canine Model ◽  
Lung Pathology ◽  
Jet Ventilation ◽  
Intermittent Mandatory Ventilation ◽  
Meconium Aspiration ◽  
High Frequency Jet Ventilation ◽  
Low Rate

Diagnosis-Related Criteria in the Consideration of Extracorporeal Membrane Oxygenation in Neonates Previously Treated With High-Frequency Jet Ventilation

PEDIATRICS ◽  
1992 ◽  
Vol 89 (3) ◽  
pp. 491-494
Author(s):  
Stephen Baumgart ◽  
Ronald B. Hirschl ◽  
Sharon Z. Butler ◽  
Christine E. Coburn ◽  
Alan R. Spitzer
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
High Frequency ◽  
Distress Syndrome ◽  
Air Leak ◽  
Jet Ventilation ◽  
Meconium Aspiration ◽  
High Frequency Jet Ventilation ◽  
Membrane Oxygenation

High-frequency jet ventilation (HFJV) is one of several high-frequency techniques that are particularly valuable for treating the neonate with lung disease refractory to conventional ventilation or with pulmonary air leak. Extracorporeal membrane oxygenation (ECMO) has also emerged as a valuable rescue therapy for neonates of more than 2000 g birth weight and 34 weeks's gestation with intractable respiratory failure. With the concurrent introduction of HFJV and ECMO, the authors sought to evaluate the role of HFJV prior to the institution of ECMO therapy. The data base for 2856 neonates receiving mechanical ventilation in one unit was used to identify 73 (of 298 total) neonates treated with HFJV, who were eligible by age and weight criteria for ECMO. Patients were grouped by diagnosis, and the oxygenation index (OI) was calculated during therapy. Outcome was evaluated for mortality, and the sensitivity of the OI for predicting mortality was calculated. Neonates who survived with HFJV alone presented with an OI of 0.30 ± 0.03 (SEM), significantly less than nonsurvivors (0.42 ± 0.04, P = .016). Survivors responded to HFJV with a rapid decrease in OI at 1 hour (0.19 ± 0.02, P < .001) and 6 hours (0.15 ± 0.01, P < .001). Nonsurvivors did not respond significantly at 1 hour (OI = 0.33 ± 0.04, P = not significant [NS]) or at 6 hours (OI = 0.40 ± 0.06, P = NS). By diagnosis, neonates with respiratory distress syndrome survived more often with HFJV (28/34, 82%) than neonates with meconium aspiration (10/26, 38%) or diaphragmatic hernia (3/9, 33%). Neonates with respiratory distress syndrome seldom presented with high OI values, but the majority of those who did survived (5/7 survived with initial OI ≥ 0.40). Neonates with meconium aspiration and a single OI ≥ 0.40 on presentation fared much worse: 13 (87%) of 15 died. From these results, it appears that neonates with severe intractable respiratory distress syndrome and/or air leak are most likely to respond favorably within 6 hours of starting HFJV. In contrast, neonates with meconium aspiration respond far less well and may require early ECMO intervention, particularly with a single OI ≥ 0.40.

Combined high-frequency jet ventilation in a meconium aspiration model

1986 ◽  
Vol 14 (1) ◽  
pp. 34-38 ◽  
Author(s):  
MARTIN KESZLER ◽  
BLANCA MOLINA ◽  
ARTHUR B. BUTTERFIELD ◽  
K. N. SIVA SUBRAMANIAN
Keyword(s):  
High Frequency ◽  
Jet Ventilation ◽  
Meconium Aspiration ◽  
High Frequency Jet Ventilation

Conventional vs high-frequency jet ventilation in a piglet model of meconium aspiration: Comparison of pulmonary and hemodynamic effects

1985 ◽  
Vol 107 (1) ◽  
pp. 115-120 ◽  
Author(s):  
Oswaldo Trindade ◽  
Ronald N. Goldberg ◽  
Eduardo Bancalari ◽  
Paulo Dickstein ◽  
Jan Ellison ◽  
...  
Keyword(s):  
High Frequency ◽  
Hemodynamic Effects ◽  
Jet Ventilation ◽  
Meconium Aspiration ◽  
High Frequency Jet Ventilation

scholarly journals Surfactant Therapy and High-Frequency Jet Ventilation in the Management of a Piglet Model of the Meconium Aspiration Syndrome

1994 ◽  
Vol 36 (4) ◽  
pp. 494-500 ◽  
Author(s):  
Thomas E Wiswell ◽  
Samuel S Peabody ◽  
Jonathan M Davis ◽  
Michael V Slayter ◽  
Rebecca C Bent ◽  
...  
Keyword(s):  
High Frequency ◽  
Meconium Aspiration Syndrome ◽  
Surfactant Therapy ◽  
Jet Ventilation ◽  
Meconium Aspiration ◽  
High Frequency Jet Ventilation

Lung lavage using high-frequency jet ventilation in rabbits with meconium aspiration

2007 ◽  
Vol 92 (3) ◽  
pp. 314-319 ◽  
Author(s):  
D Sevecova ◽  
A Calkovska ◽  
A Drgova ◽  
M Javorka ◽  
M Petraskova ◽  
...  
Keyword(s):  
High Frequency ◽  
Lung Lavage ◽  
Jet Ventilation ◽  
Meconium Aspiration ◽  
High Frequency Jet Ventilation

scholarly journals A comparison of high-frequency jet ventilation and synchronised intermittent mandatory ventilation in preterm lambs

2015 ◽  
Vol 50 (12) ◽  
pp. 1286-1293 ◽  
Author(s):  
Gabrielle C. Musk ◽  
Graeme R. Polglase ◽  
J. Bert Bunnell ◽  
Ilias Nitsos ◽  
David Tingay ◽  
...  
Keyword(s):  
High Frequency ◽  
Jet Ventilation ◽  
Intermittent Mandatory Ventilation ◽  
High Frequency Jet Ventilation
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