Gastroesophageal reflux and unexplained chronic respiratory disease in infants and children

1987 ◽  
Vol 3 (4) ◽  
pp. 208-213 ◽  
Author(s):  
A. Malfroot ◽  
Y. Vandenplas ◽  
M. Verlinden ◽  
A. Piepsz ◽  
I. Dab
Keyword(s):  
Gastroesophageal Reflux ◽  
Respiratory Disease ◽  
Chronic Respiratory Disease ◽  
Infants And Children ◽  
In Infants And Children

scholarly journals Diagnosis and Treatment of Gastroesophageal Reflux Disease in Infants and Children

2000 ◽  
Vol 14 (suppl d) ◽  
pp. 26D-34D ◽  
Author(s):  
Yvan Vandenplas
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Ph Monitoring ◽  
Chronic Respiratory Disease ◽  
Esophageal Ph Monitoring ◽  
Infants And Children ◽  
Dietary Recommendations ◽  
Esophageal Ph ◽  
In Infants And Children

Gastroesophageal reflux is a frequent, nonspecific phenomenon in infants and children. The recommended approach for infants with uncomplicated regurgitation is the reassurance of the parents about the physiological nature of excessive regurgitation, and if necessary, completed with dietary recommendations for formula-fed infants. If, despite these efforts, the symptoms persist, the administration of prokinetics such as cisapride is recommended before investigations such as esophageal pH monitoring are begun. Cisapride is the drug of choice because it has the best efficacy and safety profile. In infants and children presenting with symptoms that suggest esophagitis, endoscopy of the upper gastrointestinal tract is recommended. If there is severe esophagitis, acid suppression with H2receptor antagonists or proton pomp inhibitors is recommended, eventually in combination with prokinetics. In life-threatening situations, or in patients who are resistant to or dependent on acid suppressive medication, a surgical procedure such as laparoscopic Nissen should be considered.Esophageal pH monitoring is recommended to document gastroesophageal reflux disease in children presenting with unusual presentations such as chronic respiratory disease. Treatment consists of prokinetics and/or acid suppressive drugs, and surgery should be considered in many of these patients.

Gastroesophageal reflux and chronic respiratory disease: past, present, and future

2007 ◽  
Vol 83 (3) ◽  
pp. 196-200
Author(s):  
Yvan Vandenplas ◽  
Thierry Devreker ◽  
Bruno Hauser
Keyword(s):  
Gastroesophageal Reflux ◽  
Respiratory Disease ◽  
Chronic Respiratory Disease

RHINOVIRUS INFECTION IN CHILDREN WITH ACUTE LOWER RESPIRATORY DISEASE: EVIDENCE AGAINST ETIOLOGICAL IMPORTANCE

PEDIATRICS ◽  
1965 ◽  
Vol 35 (6) ◽  
pp. 899-905
Author(s):  
Bernard Portnoy ◽  
Herbert L. Eckert ◽  
Margaret A. Salvatore
Keyword(s):  
Respiratory Disease ◽  
Clinical Laboratory ◽  
Conclusive Evidence ◽  
Infants And Children ◽  
Concomitant Infection ◽  
Rhinovirus Infection ◽  
Etiologic Agents ◽  
Lower Respiratory Disease ◽  
In Infants And Children

The clinical, clinical laboratory, and viral aspects of 16 cases of lower respiratory disease in infants and children associated with rhinovirus isolation have been described. Rhinovirus isolations appeared to be as frequent in children without lower respiratory disease. Although the presence of concomitant infection with other viral agents made interpretation difficult, there was no conclusive evidence that the rhinoviruses were significant etiologic agents in children with lower respiratory disease severe enough to require hospitalization.

Gastroesophageal Reflux and Pulmonary Disease

PEDIATRICS ◽  
1981 ◽  
Vol 68 (1) ◽  
pp. 132-134
Author(s):  
John J. Herbst
Keyword(s):  
Gastroesophageal Reflux ◽  
Pulmonary Disease ◽  
Respiratory Disease ◽  
Chronic Respiratory Disease ◽  
Chronic Asthma ◽  
Recurrent Pneumonia ◽  
Reliable Test ◽  
The Relationship ◽  
Complex Cases

Chronic respiratory disease is a well-established complication of gastroesophageal reflux (GER).1-3 The elucidation of the relationship between the two events is hampered by the lack of a reliable test that indicates the presence or absence of GER and the lack of a test that consistently demonstrates that the pulmonary symptoms are directly caused by GER.4 In addition, GER may only contribute to the severity of the pulmonary disease, as in chronic asthma.5 In this issue of Pediatrics, Berquist et al describe their experience in evaluating 82 patients for GER who also had recurrent pneumonia or asthma.6 This article is of great value to clinicians who must care for these complex cases.

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